-
1
-
-
0030589522
-
Opportunities with phage technology and antibody engineering of fusion proteins
-
Chester KA, Hawkins RE. Opportunities with phage technology and antibody engineering of fusion proteins. Adv Drug Del Rev 1996; 22: 303-314.
-
(1996)
Adv Drug del Rev
, vol.22
, pp. 303-314
-
-
Chester, K.A.1
Hawkins, R.E.2
-
2
-
-
0029114768
-
Clinical issues in antibody design
-
Chester KA, Hawkins RE, Clinical issues in antibody design. T1BTECH 1995; 13: 294-300.
-
(1995)
T1BTECH
, vol.13
, pp. 294-300
-
-
Chester, K.A.1
Hawkins, R.E.2
-
3
-
-
0004198722
-
Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Eschericliia coli
-
Huston JS et al. Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Eschericliia coli. Proc Nail Acad Sci USA 1988; 85: 5879-5883.
-
(1988)
Proc Nail Acad Sci USA
, vol.85
, pp. 5879-5883
-
-
Huston, J.S.1
-
5
-
-
0026699293
-
Selection of phage antibodies by binding affinity: Mimicking affinity maturation
-
Hawkins RE, Russell SJ, Winter G. Selection of phage antibodies by binding affinity: mimicking affinity maturation. J Mol Biol 1992; 226: 889-896.
-
(1992)
J Mol Biol
, vol.226
, pp. 889-896
-
-
Hawkins, R.E.1
Russell, S.J.2
Winter, G.3
-
6
-
-
0028078866
-
Phage libraries for generation of clinically useful antibodies
-
Chester KA et al. Phage libraries for generation of clinically useful antibodies. Lancet 1994; 343: 455-456.
-
(1994)
Lancet
, vol.343
, pp. 455-456
-
-
Chester, K.A.1
-
7
-
-
0028989908
-
A single chain Fv derived from a filamentous phage library has distinct tumour targeting advantages over one derived from a hybridoma
-
Verhaar MJ et al. A single chain Fv derived from a filamentous phage library has distinct tumour targeting advantages over one derived from a hybridoma. Int J Cancer 1995; 61: 497-501.
-
(1995)
Int J Cancer
, vol.61
, pp. 497-501
-
-
Verhaar, M.J.1
-
8
-
-
9544250404
-
Single-chain Fv antibody selected from a combinatorial library: Clinical evidence of efficient tumour targeting
-
Begent RHJ et al. Single-chain Fv antibody selected from a combinatorial library: clinical evidence of efficient tumour targeting. Nature Med 1996; 2: 979-984.
-
(1996)
Nature Med
, vol.2
, pp. 979-984
-
-
Rhj, B.1
-
9
-
-
0027512894
-
A recombinant single chain antibody interleukin-2 fusion protein
-
Savage P, So A, Spooner RA, Epenetos AA. A recombinant single chain antibody interleukin-2 fusion protein. Br J Cancer 1993; 67: 304-310.
-
(1993)
Br J Cancer
, vol.67
, pp. 304-310
-
-
Savage, P.1
So, A.2
Spooner, R.A.3
Epenetos, A.A.4
-
10
-
-
0030974616
-
Chimeric CLL-1 antibody fusion proteins containing granulocyte-macrophage colony-stimulating factor or interleukin-2 with specificity for B cell malignancies exhibit enhanced effector functions while retaining tumor targeting properties
-
Hornick JL et al. Chimeric CLL-1 antibody fusion proteins containing granulocyte-macrophage colony-stimulating factor or interleukin-2 with specificity for B cell malignancies exhibit enhanced effector functions while retaining tumor targeting properties. Blood 1997; 89: 4437-4447.
-
(1997)
Blood
, vol.89
, pp. 4437-4447
-
-
Hornick, J.L.1
-
11
-
-
0027538181
-
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting antitumor immunity
-
Dranoff G et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting antitumor immunity. Proc Natl Acad Sci USA 1993; 90: 3539-3543.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3539-3543
-
-
Dranoff, G.1
-
12
-
-
0031046583
-
Genetic immunotherapy of established tumors with adenovirus-murine granulocyte-macrophage colony-stimulating factor
-
Lee CT et al. Genetic immunotherapy of established tumors with adenovirus-murine granulocyte-macrophage colony-stimulating factor. Hum Gene Ther 1997; 8: 187-193.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 187-193
-
-
Lee, C.T.1
-
13
-
-
0028989970
-
Idiotypic DNA vaccines against B cell lymphoma
-
Stevenson FK et al. Idiotypic DNA vaccines against B cell lymphoma. Immunol Rev 1995; 145: 211-228.
-
(1995)
Immunol Rev
, vol.145
, pp. 211-228
-
-
Stevenson, F.K.1
-
14
-
-
0024315184
-
Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M
-
Malik N et al. Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M. Mol Cell Biol 1989; 9: 2847-2853.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 2847-2853
-
-
Malik, N.1
-
15
-
-
0031055468
-
Construction of adenovirus vectors through Crelox recombination
-
Hardy S et al. Construction of adenovirus vectors through Crelox recombination. J Virol 1997; 71: 1842-1849.
-
(1997)
J Virol
, vol.71
, pp. 1842-1849
-
-
Hardy, S.1
-
16
-
-
0030999469
-
Adenovirus-mediated gene transfer: Influence of transgene, mouse strain and type of immune response on persistence of transgene expression
-
Michou AI et al. Adenovirus-mediated gene transfer: influence of transgene, mouse strain and type of immune response on persistence of transgene expression. Gene Therapy 1997; 4: 473-482.
-
(1997)
Gene Therapy
, vol.4
, pp. 473-482
-
-
Michou, A.I.1
-
17
-
-
0028559768
-
An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3
-
Bett AJ, Haddara W, Prevec L, Graham FL. An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. Proc Natl Acad Sci USA 1994; 91: 8802-8806.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8802-8806
-
-
Bett, A.J.1
Haddara, W.2
Prevec, L.3
Graham, F.L.4
-
18
-
-
0028234357
-
In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses
-
Kozarsky KF et al. In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses. J Biol Client 1994; 269: 13695-13702.
-
(1994)
J Biol Client
, vol.269
, pp. 13695-13702
-
-
Kozarsky, K.F.1
-
19
-
-
0025362523
-
In vivo tumor targeting of a recombinant singlechain antigen-binding protein
-
Colcher D et al. In vivo tumor targeting of a recombinant singlechain antigen-binding protein. J Natl Cancer Inst 1990; 82: 1191-1197.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1191-1197
-
-
Colcher, D.1
-
20
-
-
0028328261
-
Cellular immunity to viral antigens limits Eldeleted adenoviruses for gene therapy
-
Yang Y et al. Cellular immunity to viral antigens limits Eldeleted adenoviruses for gene therapy. Proc Natl Acad Sci USA 1994; 91: 4407-4411.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4407-4411
-
-
Yang, Y.1
-
21
-
-
0028246338
-
Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver
-
Engelhardt JF, Ye X, Doranz B, Wilson JM. Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver. Proc Natl Acad Sci USA 1994; 91: 6196-6200.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6196-6200
-
-
Engelhardt, J.F.1
Ye, X.2
Doranz, B.3
Wilson, J.M.4
-
22
-
-
0027521773
-
Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice
-
Smith TA et al. Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice. Nat Genet 1993; 5: 397-402.
-
(1993)
Nat Genet
, vol.5
, pp. 397-402
-
-
Smith, T.A.1
-
23
-
-
0028318416
-
Safety and efficacy of repetitive adenovirusmediated transfer of CFTR cDNTA to airway epithelia of primates and cotton rats
-
Zabner J et al. Safety and efficacy of repetitive adenovirusmediated transfer of CFTR cDNTA to airway epithelia of primates and cotton rats. Nat Genet 1994; 6: 75-83.
-
(1994)
Nat Genet
, vol.6
, pp. 75-83
-
-
Zabner, J.1
-
24
-
-
0030480876
-
Nondepleting anti-CD4 antibody treatment prolongs lung-directed El-deleted adenovirus-mediated gene expression in rats
-
Lei D et al. Nondepleting anti-CD4 antibody treatment prolongs lung-directed El-deleted adenovirus-mediated gene expression in rats. Hum Gene Ther 1996; 7: 2273-2279.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 2273-2279
-
-
Lei, D.1
-
25
-
-
0029743163
-
Cyclophosphamide diminishes inflammation and prolongs transgene expression following delivery of adenoviral vectors to mouse liver and lung
-
Jooss K, Yang Y, Wilson JM. Cyclophosphamide diminishes inflammation and prolongs transgene expression following delivery of adenoviral vectors to mouse liver and lung. Hum Gene Ther 1996; 7: 1555-1566.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1555-1566
-
-
Jooss, K.1
Yang, Y.2
Wilson, J.M.3
-
26
-
-
0029113869
-
Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration
-
Kay MA et al. Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration. Nat Genet 1995; 11: 191-197.
-
(1995)
Nat Genet
, vol.11
, pp. 191-197
-
-
Kay, M.A.1
-
27
-
-
0029943155
-
A new adenoviral vector: Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and -galactosidase
-
Kochanek S et al. A new adenoviral vector: replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and -galactosidase. Proc Nail Acad Sci USA 1996; 93: 5731-5736.
-
(1996)
Proc Nail Acad Sci USA
, vol.93
, pp. 5731-5736
-
-
Kochanek, S.1
-
28
-
-
0029966514
-
Recombinant adenovirus deleted of all viral genes for gene therapy of cystic fibrosis
-
Fisher KJ et al. Recombinant adenovirus deleted of all viral genes for gene therapy of cystic fibrosis. Virology 1996; 217: 11-22.
-
(1996)
Virology
, vol.217
, pp. 11-22
-
-
Fisher, K.J.1
-
29
-
-
0031049699
-
Persistence in muscle of an adenoviral vector that lacks all viral genes
-
Chen HH et al. Persistence in muscle of an adenoviral vector that lacks all viral genes. Proc Natl Acad Sci USA 1997; 94:1645-1650.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1645-1650
-
-
Chen, H.H.1
-
30
-
-
0030761734
-
Development of an adenovirus vector with tetracycline-regulatable human tumor necrosis factor a gene expression
-
Hu SX et al. Development of an adenovirus vector with tetracycline-regulatable human tumor necrosis factor a gene expression. Cancer Res 1997; 57: 3339-3343.
-
(1997)
Cancer Res
, vol.57
, pp. 3339-3343
-
-
Hu, S.X.1
-
31
-
-
0031962433
-
Efficient transgene regulation from a single tetracycline-controlled positive feedback regulatory system
-
Agha-Mohammedi S, Hawkins RE. Efficient transgene regulation from a single tetracycline-controlled positive feedback regulatory system. Gene Therapy 1998; 5: 76-84.
-
(1998)
Gene Therapy
, vol.5
, pp. 76-84
-
-
Agha-Mohammedi, S.1
Hawkins, R.E.2
-
32
-
-
16944367354
-
Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype
-
Mack ÇA et al. Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype. Hum Gene Ther 1997; 8: 99-109.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 99-109
-
-
Mack, Ç.A.1
-
33
-
-
0031049765
-
Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery
-
Liu Y et al. Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery. Nat Biotechnol 1997; 15: 167-173.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 167-173
-
-
Liu, Y.1
-
34
-
-
0029977935
-
Heart muscle-specific gene expression using replication defective recombinant adenovirus
-
Rothmann T et al. Heart muscle-specific gene expression using replication defective recombinant adenovirus. Gene Therapy 1996; 3: 919-926.
-
(1996)
Gene Therapy
, vol.3
, pp. 919-926
-
-
Rothmann, T.1
-
35
-
-
0030831076
-
The adenobody approach to viral targeting: Specific and enhanced adenoviral gene delivery
-
VVatkins SJ, Mesyanzhinov W, Kurochkina LP, Hawkins RE. The adenobody approach to viral targeting: specific and enhanced adenoviral gene delivery. Gene Tlierapy 1997; 4: 1004-1012.
-
(1997)
Gene Tlierapy
, vol.4
, pp. 1004-1012
-
-
Vvatkins, S.J.1
Mesyanzhinov, W.2
Kurochkina, L.P.3
Hawkins, R.E.4
-
36
-
-
0026519867
-
Cell selection strategies for making antibodies from variable gene libraries: Tapping the memory pool
-
Hawkins RE, Winter G. Cell selection strategies for making antibodies from variable gene libraries: tapping the memory pool. Eur J Immunol 1992; 22: 867-870.
-
(1992)
Eur J Immunol
, vol.22
, pp. 867-870
-
-
Hawkins, R.E.1
Winter, G.2
-
37
-
-
0022552131
-
Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
-
Kozak M. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. CeH 1986; 44: 283-292.
-
(1986)
CeH
, vol.44
, pp. 283-292
-
-
Kozak, M.1
-
38
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
-
Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979; 76: 4350-4354.
-
(1979)
Proc Natl Acad Sci USA
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
39
-
-
0018971212
-
Growth of factor-dependent hemopoietic precursor cell lines
-
Dexter TM et al. Growth of factor-dependent hemopoietic precursor cell lines. J Exp Med 1980; 152: 1036-1047.
-
(1980)
J Exp Med
, vol.152
, pp. 1036-1047
-
-
Dexter, T.M.1
|