A sequential study of circulating immune complexes, complement and immunoglobulins in borderline tuberculoid leprosy patients with and without reactions

Indian Journal of Leprosy

Volumn 70, Issue 2, 1998, Pages 153-160

  Ramanathan, V D ^a   Thyagi, P ^b   Ramanathan, U ^a   Katoch, K ^c   Ramu, G ^d  

^a NATIONAL INSTITUTE FOR RESEARCH IN TUBERCULOSIS   (India)

^b NATIONAL INSTITUTE OF MALARIA RESEARCH   (India)

^c NATIONAL JALMA INSTITUTE FOR LEPROSY AND OTHER MYCOBACTERIAL DISEASES   (India)

^d G KUPPUSWAMY NAIDU MEMORIAL HOSPITAL   (India)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3D; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ADULT; ANTIBODY TITER; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COMPLEMENT BLOOD LEVEL; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; ERYTHEMA NODOSUM LEPROSUM; FEMALE; HUMAN; IMMUNE COMPLEX DEPOSITION; MALE; REVERSAL REACTION; TREATMENT OUTCOME; TUBERCULOID LEPROSY;

ADULT; ANTIGEN-ANTIBODY COMPLEX; COMPLEMENT C3D; FEMALE; HUMANS; IMMUNOGLOBULINS; LEPROMIN; LEPROSTATIC AGENTS; LEPROSY, TUBERCULOID; MALE; MIDDLE AGED; TIME FACTORS;

EID: 0031828952     PISSN: 02549395     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Chakrabarty AK, Kashyap A, Sehgal VN, Saha K 1988. Solubilization of preformed immune complexes in sera of patients with type 1 and type 2 lepra reactions. Int J Lepr 56: 559-565.
2. Hudson L, Hay FC 1980. Practical Immunology, Oxford, Blackwell Scientific Publications, p 243.
3. IAL 1984. Summary of the seminar on consensus on treatment regimens in leprosy and problems of drug delivery. Indian J Lepr 56: 158-159.
4. Lachmann PJ, Hobart MJ 1978. Complement technology. In Handbook of Experimental Immunochemistry, ed DM Weir, Oxford, Blackwell Scientific Publications, p 54-57.
5. Lanjendijk EJMT, van Diepen TW, Harboe M, Belehu A 1983. Relation between anti-Mycobacterium leprae antibody activity and clinical features in borderline tuberculoid (BT) leprosy. Int J Lepr 51: 305-311.
6. Law SK, Dodds AW 1997. The internal thioester and the covalent binding properties of the complement proteins C3 and C4, A review. Protein Science 6: 263-274.
7. Nilsen R, Mshana RN, Negesse Y et al 1986. Immunohistochemical studies of leprous neuritis. Lepr Rev 57: (Suppl 2) 177-187.
8. Packard BD, Weiler JM 1983. Steroids inhibit the activation of the alternative amplification pathway of complement. Infect Immun 40: 1011-1014.
9. Ramanathan VD, Parkash O, Ramu G et al 1984. Isolation and analysis of circulating immune complexes in leprosy. Clin Immunol Immunopathol 32: 261-268.
10. Ramanathan VD, Sharma P, Ramu G, Sengupta U 1985. Reduced complement-mediated immune complex solubilization in leprosy patients. Clin Exp Immunol 60: 553-558.
11. Ramanathan VD, Tyagi P, Ramanathan U et al 1991. Persistent reduced solubilization of immune complexes in lepromatous patients with reactions. Int J Lepr 59: 5-11.
12. Ridley DS, Jopling WH 1966. Classification of leprosy according to immunity. A five group system. Int J Lepr 34: 255-273.
13. Saha K, Chakrabarty AK, Sharma V, Sehgal VN 1982. An appraisal of third complement component (C3) and breakdown product (C3d) in erythema nodosum leprosum (ENL). Lepr Rev 53: 253-260.
14. Saha K, Chattopadhya D, Kashyap A et al 1995. Enhanced response of serum IgG class of anti -PGL 1 antibodies in leprosy patients during onset and following clinical remission of type 1 and type 2 reactions. Int J Lepr 63: 105-108.
15. Sengupta U, Ramu G, Desikan KV 1979. Assessment of Dharmendra antigen. Standardization of the antigen. Lepr India 51: 316-329.
16. Takahashi M, Takahashi S, Hirose S 1980. Solubilization of antigen-antibody complexes. A new function of complement as a regulator of immune reactions. Prog Allergy 27: 134-166.