Pain reduction in lidocaine administration through buffering and warming

American Journal of Emergency Medicine

Volumn 16, Issue 4, 1998, Pages 353-356

  Colaric, Kenneth B ^a   Overton, David T ^b,d   Moore, Karen ^c  

^a Methodist Hospital   (Canada)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c BORGESS MEDICAL CENTER   (United States)

^d MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Lidocaine; Local anesthetics; Pain measurement

Indexed keywords

BUFFER; LIDOCAINE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; HUMAN; HUMAN EXPERIMENT; INJECTION PAIN; LOCAL ANESTHESIA; NORMAL HUMAN; PAIN ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SUBCUTANEOUS DRUG ADMINISTRATION; WARMING;

EID: 0031828323     PISSN: 07356757     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-6757(98)90126-7     Document Type: Article

References (35)

1. Arndt KA: Minimizing the pain of local anesthesia. Clin Exp Dermatol 1992;17:217
2. Lugo-Janer G, Padial M, Sanchez J: Less painful alternatives for local anesthesia. J Dermatol Surg Oncol 1993;19:237-240
3. Martin AJ: pH-adjustment and discomfort by the intradermal injection of lignocaine. Anaesthesia 1990;45:975-978
4. Christoph RA, Buchanan L, Begalla K, et al: Pain reduction in local anesthetic administration through pH buffering. Ann Emerg Med 1988;17:117-120
5. Bartfield JM, Homer PJ, Ford DT, et al: Buffered lidocaine as a local anesthetic: An investigation of shelf life. Ann Emerg Med 1992;21:16-19
6. Harrison PV, Merckel J: Does lignocaine temperature alter pain perception during cutaneous local anesthesia? Clin Exp Dermatol 1991;16:312
7. Kaplan PA, Lieberman RP, Vonk BM: Does heating lidocaine decrease the pain of injection? AJR Am J Roentgenol 1987;149:1291
8. Bartfield JM, Crisafulli KM, Raccio-Robak K, et al: The effects of warming and buffering on pain of infiltration of lidocaine. Acad Emerg Med 1995;2:254-258
9. Finkel LI, Berg DJ: Heating lidocaine appears to prevent painful injection. AJR Am J Roentgenol 1987;148:651
10. Scott J, Huskisson EC: Graphic representation of pain. Pain 1976;2:176-184
11. Hicks CR: Fundamental Concepts in the Design of Experiments (ed 3). New York, NY, Holt, Rinehart and Winston, 1982
12. Brogan GX, Giarrusso E, Hollander JE, et al: Comparison of plain, warmed and buffered Lidocaine for anesthesia of traumatic wounds. Ann Emerg Med 1995;26:121-125
13. Arndt KA, Burton C, Noe JM: Minimizing the pain of local anesthesia. Plast Reconstr Surg 1983;72:676-679
14. Norris RL: Local anesthetics. Emerg Med Clin North Am 1992;10:707-717
15. Orlinsky M, Hudson C, Chan L, et al: Pain comparison of unbuffered versus buffered lidocaine in local wound infiltration. J Emerg Med 1992;10:411-415
16. Bancroft JW, Benenati JF, Becker GJ, et al: Neutralized lidocaine: Use in pain reduction in local anesthesia. J Vasc Int Radiol 1992;3:107-109
17. Crose VW: Pain reduction in local anesthetic administration through pH buffering. J Indiana Dent Assoc 1991;70:24-27
18. Metzinger SE, Rigby PL, Bailey DJ, et al: Local anesthesia in blepharoplasty: A new look? South Med J 1994;87:225-227
19. Larson PO, Ragi G, Swandby M, et al: Stability of buffered lidocaine and epinephrine used for local anesthesia. J Dermatol Surg Oncol 1991;17:411-414
20. Bainbridge LC: Comparison of room temperature and body temperature local anesthetic solutions. Br J Plast Surg 1991;44: 147-148
21. Cragg AH, Berbaum K, Smith TP: A prospective blinded trial of warm and cold lidocaine for intradermal injection. AJR Am J Roentgenol 1988;150:1183-1184
22. Alonso PE, Perula LA, Rioja LF: Pain-temperature relation in the application of local anesthesia. Br J Plast Surg 1993;46:76-78
23. Chilvers CR: Warm local anaesthetic - Effect on latency of onset of axillary brachial plexus block. Anaesth Intens Care 1993;21: 795-798
24. Rood JP: The temperature of local anaesthetic solutions. J Dentistry 1977;5:213-214
25. Peterson DS, Kein DR: Pain sensation related to local anesthesia injected at varying temperatures. Anesthesia Progress 1978;5: 164-165
26. Dalton AM, Sharma A, Redwood M, et al: Does the warming of local anaesthetic reduce the pain of its injection? Arch Emerg Med 1989;6:247-250
27. Davidson JA, Boom SJ: Warming lignocaine to reduce pain associated with injection. BMJ 1992;305:617-618
28. Martin S, Jones JS, Wynn BN: Does warming local anesthetic reduce the pain of subcutaneous injection? Am J Emerg Med 1996;14:10-12
29. Mader TJ, Playe SJ, Garb JL: Reducing the pain of local anesthetic infiltration: Warming and buffering have a synergistic effect. Ann Emerg Med 1994;23:550-554
30. Tornay PL, Tornay TC, Hoffman J, et al: Heated versus buffered lidocaine and the pain on local injection: A comparative study. Ann Emerg Med 1994;23:629 (abstr)
31. Todd KH, Funk JP: The minimum clinically important difference in physician-assigned visual analog pain scores. Acad Emerg Med 1996;2:142-146
32. Todd KH, Funk KG, Funk JP, et al: Clinical significance of reported changes in pain severity. Ann Emerg Med 1996;27:485-489
33. Todd KH: Clinical versus statistical significance in the assessment of pain relief. Ann Emerg Med 1996;27:439-441
34. Wells GA, Tugwell P, Kraag GR: Minimum important difference between patients with rheumatoid arthritis: The patient's perspective. J Rheumatol 1993;20:557-560
35. Wright JM, Price SD, Watson WA: NSAID use and efficacy in the emergency department. Ann Pharmacother 1994;28:1202 (letter)