Expression of costimulatory molecule CD80 on peripheral blood T cells in patients with systemic lupus erythematosus

Journal of Rheumatology

Volumn 25, Issue 6, 1998, Pages 1085-1091

  Takasaki, Yoshinari ^a   Ogaki, Makoto ^b   Abe, Kaori ^a   Takeuchi, Ken ^a   Ando, Soichiro ^a   Tokano, Yoshiaki ^a   Kobayashi, Shigeto ^a   Sekigawa, Iwao ^a   Tsuda, Hiroshi ^a   Hashimoto, Hiroshi ^a  

^a JUNTENDO UNIVERSITY   (Japan)

^b MITSUBISHI CHEMICAL CORPORATION   (Japan)

Author keywords

CD80; Costimulatory molecule; Peripheral blood lymphocyte; SLE; T cell

Indexed keywords

B7 ANTIGEN; CD19 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 2 RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HELPER CELL; HUMAN; HUMAN CELL; MALE; MIXED CONNECTIVE TISSUE DISEASE; MONONUCLEAR CELL; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE SUBPOPULATION;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD80; ARTHRITIS, RHEUMATOID; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; MONOCYTES; PHENOTYPE; SEVERITY OF ILLNESS INDEX;

EID: 0031828262     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Muller DL, Jenkins MK, Schwartz RH. Clonal expansion versus functional clonal inactivation: a costimulatory signaling pathway determines the outcome of T cell antigen receptor occupancy. Annu Rev Immunol 1989;7:445-80.
2. Schwartz RH. A cell culture model for T lymphocyte clonal anergy. Science 1990;248:1349-56.
3. Weaver CT, Unanue ER. The costimulatory functions of antigen-presenting cells, Immunol Today 1990;11:49-55.
4. Thompson CB, Lindsten T, Ledbetter JA, et al. CD28 activation pathway regulates the production of multiple T cell-derived lymphokines/cytokines. Proc Natl Acad Sci USA 1989;86:1333-7.
5. Lindsten T, June CH, Ledbetter JA, Stella G, Thompson CB. Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway. Science 1989;244:339-43.
6. Linsley PS, Brady W, Grosmaire L, Aruffo A, Damle NK, Ledbetter JA. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation. J Exp Med 1991;173:721-30.
7. Harding FA, McArthur JG, Gross JA, Raulet PH, Allison JP. CD28 mediated signaling co-stimulates murine T cells and prevents induction of anergy in T cell clones. Nature 1992;356:607-9.
8. Tan P, Anasetti C, Hansen JA, et al. Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interactions of CD28 with its natural ligand B7/BB1. J Exp Med 1993;177:165-73.
9. Gimmi CD, Freeman GL, Gribben JG, Gray G, Nadler LM: Human T cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation. Proc Natl Acad Sci USA 1993;90:6586-90.
10. Linsley PS, Ledbetter JA. The role of the CD28 receptor during T cell responses to antigen. Annu Rev Immunol 1993;11:191-212.
11. Harper K, Balzano C, Rouvier E, Mattei MG, Lueiani MF, Golstein P. CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location. J Immunol 1991;147:1037-44.
12. Schwartz RH. Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in IL-2 production and immunotherapy. Cell 1992;71:1065-8.
13. Azuma M, Yssel H, Phillips JH, Spits H, Lanier LL. Functional expression of B7/BB1 on activated T lymphocytes. J Exp Med 1993;177:845-50.
14. Wyss-Coray T, Mauri-Hellweg D, Baumann K, Bettens F, Grunow R, Pichler WJ. The B7 adhesion molecule is expressed on activated human T cells: functional involvement in T-T cell interactions. Eur J Immunol 1993;23:2175-80.
15. Sansom DM, Hall ND. B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells in vitro. Eur J Immunol 1993;23:295-8.
16. Nickoloff BJ, Nestle FO, Zheng XG, Turka LA. T lymphocytes in skin lesion of psoriasis and mycosis fungoides express B7-1: a ligand for CD28. Blood 1994;83:2580-6.
17. Verwilghen J, Lovis R, Boer MD, et al. Expression of functional B7 and CTLA-4 on rheumatoid synovial T cells. J Immunol 1994;153:1378-85.
18. Barnaba V, Watts C, Boer MD, Lane P, Lanzavecchia A. Professional presentation of antigen by activated T cells. Eur J Immunol 1994;24:71-5.
19. Fu SM, Chiorazzi N, Wang CY, et al. Ia bearing T lymphocytes in man: their identification and role in the generation of allogenic helper activity. J Exp Med 1978;148:1423-8.
20. Yu DTY, Winchester RJ, Fu SM, Gibofsky A, Ko HS, Kunkel HG. Peripheral blood Ia-positive T cells. J Exp Med 1980;151:91-100.
21. Hishikawa T, Tokano Y, Sekigawa I, et al. HLA-DP+ T cells and deficient interleukin-2 production in patients with systemic lupus erythematosus. Clin Immunol Pathol 1990;55:285-96.
22. Uchiyama T, Broder S, Waldman TA. A monoclonal anti-body (anti-Tac) reactive with activated and functional mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac cells. J Immunol 1981;126:1393-7.
23. Wigfall DR, Sakai RS, Wallace DJ, Jordan SC. Interleukin-2 receptor expression in peripheral blood lymphocytes from systemic lupus erythematosus patients: relationship to clinical activity. Clin Immunol Immunopathol 1988;47:354-62.
24. Murashima A, Takasaki Y, Ohgaki M, Hashimoto H, Hirose S. Activated peripheral blood mononuclear cells detected by murine monoclonal antibodies to proliferating cell nuclear antigen in active lupus patients. J Clin Immunol 1990;10:28-37.
25. Tokano Y, Murashima A, Takasaki Y, Hashimoto H, Okumura K, Hirose S. Relation between soluble interleukin 2 receptor and clinical findings in patients with systemic lupus erythematosus. Ann Rheum Dis 1989;48:803-9.
26. Tan EM, Cohen AS, Fries JE, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-7.
27. Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
28. Kasukawa R, Tojo T, Miyawaki S, et al. Preliminary diagnostic criteria for classification of mixed connective tissue disease. In: Kasukawa R, Sharp GC, editors. Mixed connective tissue disease and antinuclear antibodies. Excerpta Medica International Congress Series 719. Amsterdam: Elsevier Science; 1987:41-7.
29. Bombardier C, Gladman DD, Urowitz MB, et al. Derivation of the SLEDAI. A disease activity index for lupus patients. Arthritis Rheum 1992;35:630-40.
30. Yokochi T, Holly RD, Clark EA. B lymphoblast antigen (BB-1) expressed on Epstein-Barr virus-activated B cell blasts, B lymphoblastoid cell lines, and Burkitt's lymphomas. J Immunol 1982;128:823-7.
31. Freedman AS, Freeman G, Horowitz JC, Daley J, Nadler LM. B7, a B cell-restricted antigen that identifies preactivated B cells. J Immunol 1987;139:3260-7.
32. Young JW, Koulova L, Soergel SA, Clark EA, Steinman RM, Dupont B. The B7/BB1 antigen provides one of several costimulatory signals for the activation of CD4+ T lymphocytes by human blood dendritic cells in vitro. J Clin Invest 1992;90:229-37.
33. Ranheim EA, Kipps TJ. Elevated expression of CD80 (B7/BB1) and other accessory molecules on synovial fluid mononuclear cells subsets in rheumatoid arthritis. Arthritis Rheum 1994;37:1637-46.
34. Pichler WJ, Wyss-Coray T. T cells as antigen-presenting cells. Immunol Today 1994;15:312-5.
35. Mauri D, Wyss-Cory T, Gallati H, Pichler WJ. Antigen-presenting T cells induce the development of cytotoxic T cells. I. Involvement of the CD80-CD28 adhesion molecules. J Immunol 1995;155:118-27.
36. Folzenlogen D, Hofer MF, Leung DYM, Freed JH, Newell MK. Analysis of CD80 and CD86 expression on peripheral blood B lymphocytes reveals increased expression of CD86 in lupus patients. CHn Immunol Immunopathol 1997;83:199-204.
37. Nakajima A, Azuma M, Kodera S, et al. Preferential dependence of autoantibody production in murine lupus on CD86 costimulatory molecule. Eur J Immunol 1995;25:3060-96.