Regulation of the spvR gene of the Salmonella typhimurium virulence plasmid during exponential-phase growth in intracellular salts medium and at stationary phase in L broth

Microbiology

Volumn 144, Issue 7, 1998, Pages 1823-1833

  Wilson, Julie A ^a,b   Gulig, Paul A ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

Expression; Regulation; Salmonella typhimurium; Virulence

Indexed keywords

SIGMA FACTOR;

ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; GENE CONTROL; NONHUMAN; OPERON; PLASMID; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM;

BACTERIA (MICROORGANISMS); MAMMALIA; NEGIBACTERIA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0031828034     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-144-7-1823     Document Type: Article

References (52)

1. Abe, A. & Kawahara, K. (1995). Transcriptional regulation and promoter sequence of the spvR gene of virulence plasmid pKDSC50 in Salmonella choleraesuis serovar Choleraesuis. FEMS Microbiol Lett 129, 225-230.
2. Abe, A., Matsui, H., Danbara, H., Tanaka, K., Takahashi, H. & Kawahara, K. (1994). Regulation of spvR gene expression of Salmonella virulence plasmid pKDSC50 in Salmonella choleraesuis serovar Choleraesuis. Mol Microbiol 12, 779-787.
3. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A. & Struhl, K. (1993). Current Protocols in Molecular Biology. New York: Wiley Interscience.
4. Caldwell, A. L. & Gulig, P. A. (1991). The Salmonella typhimurium virulence plasmid encodes a positive regulator of a plasmid-encoded virulence gene. J Bacteriol 173, 7176-7185.
5. Chang, A. C. & Cohen, S. N. (1978). Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. J Bacteriol 134, 1141-1156.
6. Chen, C. Y., Buchmeier, N. A., Libby, S., Fang, F. C., Krause, M. & Guiney, D. G. (1995). Central regulatory role for the RpoS sigma factor in expression of Salmonella dublin plasmid virulence genes. J Bacteriol 177, 5303-5309.
7. Coynault, C., Robbe-Saule, V., Popoff, M. Y. & Norel, F. (1992). Growth phase and SpvR regulation of transcription of Salmonella typhimurium spvABC virulence genes. Microb Pathog 13, 133-143.
8. Deretic, V., Gill, J. F. & Chakrabarty, A. M. (1987). Gene algD coding for GDP mannose dehydrogenase is transcriptionally activated in mucoid Pseudomonas aeruginosa. J Bacteriol 169, 351-358.
9. Donnenberg, M. S. & Kaper, J. B. (1991). Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector. Infect Immun 59, 4310-4317.
10. El-Gedaily, A., Paesold, G., Chen, C-Y., Guiney, D. G. & Krause, M. (1997a). Plasmid virulence gene expression induced by short-chain fatty acids in Salmonella dublin: identification of rpoS-dependent and rpoS-independent mechanisms. J Bacteriol 179, 1409-1412.
11. El-Gedaily, A., Paesold, G. & Krause, M. (1997b). Expression profile and subcellular location of the plasmid-encoded virulence (Spv) proteins in wild-type Salmonella dublin. Infect Immun 35, 3406-3411.
12. Errington, J. (1986). A general method for fusion of the Escherichia coli lacZ gene to chromosomal genes in Bacillus subtilis. J Gen Microbiol 132, 2953-2966.
13. Fang, F. C. & Fierer, J. (1991). Human infection with Salmonella dublin. Medicine 70, 198-207.
14. Fang, F. C., Krause, M., Roudier, C., Fierer, J. & Guiney, D. G. (1991). Growth regulation of a Salmonella plasmid gene essential for virulence. J Bacteriol 173, 6783-6789.
15. Fang, F. C., Libby, S. J., Buchmeier, N. A., Loewen, P. C., Switala, J., Harwood, J. & Guiney, D. G. (1992). The alternative sigma factor KatF (RpoS) regulates Salmonella virulence. Proc Natl Acad Sci USA 89, 11978-11982.
16. Fierer, J., Krause, M., Tauxe, R. & Guiney, D. (1992). Salmonella typhimurium bacteremia: association with the virulence plasmid. J Infect Dis 166, 639-642.
17. Galan, J. E., Timoney, J. F. & Curtiss, R., III (1988). Expression and localization of the Streptococcus equi M protein in Escherichia coli and Salmonella typhimurium. In Proceedings of the Fifth International Conference on Equine Infectious Diseases, pp. 34-40. Edited by D. G. Powell. Lexington: University Press of Kentucky.
18. Grob, P. & Guiney, D. G. (1996). In vitro binding of the Salmonella dublin virulence plasmid regulatory protein SpvR to the promoter regions of spvA and spvR. J Bacteriol 178, 1813-1820.
19. Grob, P., Kahn, D. & Guiney, D. G. (1997). Mutational characterization of promoter regions recognized by the Salmonella dublin virulence plasmid regulatory protein SpvR. J Bacteriol 179, 5398-5406.
20. Gulig, P. A. & Curtiss, R., III (1987). Plasmid-associated virulence of Salmonella typhimurium. Infect Immun 55, 2891-2901.
21. Gulig, P. A. & Doyle, T. J. (1993). The Salmonella typhimurium virulence plasmid increases the growth rate of salmonellae in mice. Infect Immun 61, 504-511.
22. Gulig, P. A., Caldwell, A. L. & Chiodo, V. A. (1992). Identification, genetic analysis and DNA sequence of a 7.8-kilobase virulence region of the Salmonella typhimurium virulence plasmid. Mol Microbiol 6, 1395-1411.
23. Gulig, P. A., Danbara, H., Guiney, D. G., Lax, A. J., Norel, F. & Rhen, M. (1993). Molecular analysis of virulence genes of the Salmonella virulence plasmids. Mol Microbiol 7, 825-830.
24. Gulig, P. A., Doyle, T. J., Hughes, J. A. & Matsui, H. (1998). Analysis of host cells associated with Spv-mediated increased intracellular growth rate of Salmonella typhimurium in mice. Infect Immun 66, 2471-2485.
25. Headley, V. L. & Payne, S. M. (1990). Differential protein expression by Shigella flexneri in intracellular and extracellular environments. Proc Natl Acad Sci USA 87, 4179-4183.
26. Heiskanen, P., Taira, S. & Rhen, M. (1994). Role of rpoS in the regulation of Salmonella plasmid virulence (spv) genes. FEMS Microbiol Lett 123, 125-130.
27. Heithoff, D. M., Conner, C. P., Hanna, P. C., Julio, S. M., Hentschel, U. & Mahan, M. J. (1997). Bacterial infection as assessed by in vivo gene expression. Proc Natl Acad Sci USA 94, 934-939.
28. s as a global regulator in the osmotic control of gene expression in Escherichia coli. Mol Microbiol 21, 887-893.
29. Hitchcock, P. J. & Brown, T. M. (1983). Morphological heterogeneity among Salmonella lipopolysaccharide chemotypes in silver-stained polyacrylamide gels. J Bacteriol 154, 269-277.
30. Jishage, M., Iwata, A., Ueda, S. & lshihama, A. (1996). Regulation of RNA polymerase sigma subunit synthesis in Escherichia coli: intracellular levels of four species of sigma subunit under various growth conditions. J Bacteriol 178, 5447-5451.
31. Kowarz, L., Coynault, C., Robbe Saule, V. & Norel, F. (1994). The Salmonella typhimurium katF (rpoS) gene: cloning, nucleotide sequence and regulation of spvR and spvABCD virulence plasmid genes. J Bacteriol 176, 6852-6860.
32. Kowarz, L., Robbe Saule, V. & Norel, F. (1996). Identification of cis-acting DNA sequences involved in the transcription of the virulence regulatory gene spvR in Salmonella typhimurium. Mol Gen Genet 251, 225-235.
33. Krause, M., Fang, F. C. & Guiney, D. G. (1992). Regulation of plasmid virulence gene expression in Salmonella dublin involves an unusual operon structure. J Bacteriol 174, 4482-4489.
34. Krause, M., Fang, F. C., El-Gedaily, A., Libby, S. & Guiney, D. G. (1995). Mutational analysis of SpvR binding to DNA in the regulation of the Salmonella plasmid virulence operon. Plasmid 34, 37-47.
35. Lennox, E. S. (1955). Transduction of linked genetic characters of the host by bacteriophage P1. Virology 1, 190-206.
36. Maniatis, T., Fritsch, E. F. & Sambrook, J. (1982). Molecular Cloning: a Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
37. Matsui, H., Abe, A., Kawahara, K., Terakado, N. & Danbara, H. (1991). Positive regulator for the expression of Mba protein of the virulence plasmid, pKDSC50, of Salmonella choleraesuis. Microb Pathog 10, 459-464.
38. Matsui, H., Abe, A., Suzuki, S., Kijima, M., Tamura, Y., Nakamura, M., Kawahara, K. & Danbara, H. (1993). Molecular mechanism of the regulation of expression of plasmid-encoded mouse bacteremia (mba) genes in Salmonella serovar choleraesuis. Mol Gen Genet 236, 219-226.
39. Miller, J. H. (1972). Assay of beta-galactosidase. In Experiments in Molecular Genetics, pp. 353-355. Edited by J. H. Miller. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
40. Montenegro, M. A., Morelli, G. & Helmuth, R. (1991). Hetero-duplex analysis of Salmonella virulence plasmids and their prevalence in isolates of defined sources. Microb Pathog 11, 391-397.
41. 32 in Escherichia coli. J Bacteriol 179, 445-452.
42. O'Byrne, C. P. & Dorman, C. J. (1994a). Transcription of the Salmonella typhimurium spv virulence locus is regulated negatively by the nucleoid-associated protein H-NS. FEMS Microbiol Lett 121, 99-105.
43. O'Byrne, C. P. & Dorman, C. J. (1994b). The spv virulence operon of Salmonella typhimurium LT2 is regulated negatively by the cyclic AMP (cAMP)-cAMP receptor protein system. J Bacteriol 176, 905-912.
44. Rogers, J. A. & Gulig, P. A. (1994). Expression and molecular regulation of the spvR gene of the Salmonella typhimurium virulence plasmid. In Abstracts of the 94th Annual Meeting of the American Society for Microbiology, abstract B323. Washington DC: American Society for Microbiology.
45. Rogers, J. A., Matsui, H. & Gulig, P. A. (1995). spvA of the Salmonella typhimurium virulence plasmid can act as a transcriptional repressor of spvR and is not essential for virulence in orally inoculated mice. In Abstracts of the 94th Annual Meeting of the American Society for Microbiology, abstract B304. Washington DC: American Society for Microbiology.
46. Roudier, C., Fierer, J. & Guiney, D. G. (1992). Characterization of translation termination mutations in the spv operon of the Salmonella virulence plasmid pSDL2. J Bacteriol 174, 6418-6423.
47. Simon, R., Priefer, U. & Pühler, A. (1983). A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in gram negative bacteria. Bio/Technology 1, 784-791.
48. Spink, J. M., Pullinger, G. D., Wood, M. W. & Lax, A. J. (1994). Regulation of spvR, the positive regulatory gene of Salmonella plasmid virulence genes. FEMS Microbiol Lett 116, 113-121.
49. Taira, S., Riikonen, P., Saarilahti, H., Sukupolvi, S. & Rhen, M. (1991). The mkaC virulence gene of the Salmonella serovar Typhimurium 96 kb plasmid encodes a transcriptional activator. Mol Gen Genet 228, 381-384.
50. Taira, S., Heiskanen, P., Hurme, R., Heikkila, H., Riikonen, P. & Rhen, M. (1995). Evidence for functional polymorphism of the spvR gene regulating virulence gene expression in Salmonella. Mol Gen Genet 246, 437-444.
51. Valone, S. E., Chikami, G. K. & Miller, V. L. (1993). Stress induction of the virulence proteins (SpvA, -B, and -C) from native plasmid pSDL2 of Salmonella dublin. Infect Immun 61, 705-713.
52. Wilson, J. A., Doyle, T. J. & Gulig, P. A. (1997). Exponential-phase expression of spvA of the Salmonella typhimurium virulence plasmid: induction in intracellular salts medium and intracellularly in mice and cultured mammalian cells. Microbiology 143, 3827-3839.