Effect of age on the levels of retinol and retinyl esters in blood plasma, liver and kidney of dogs

International Journal for Vitamin and Nutrition Research

Volumn 68, Issue 4, 1998, Pages 237-241

  Schweigert, Florian J ^a,b   Buchholz, Ingeborg ^a   Bonitz, Katharina ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY OF POTSDAM   (Germany)

Author keywords

Development; Dog; Tissue Distribution; Vitamin A

Indexed keywords

ESTER; RETINOL;

AGING; ANIMAL; ARTICLE; BLOOD; DOG; FEMALE; KIDNEY; LIVER; MALE; METABOLISM;

AGING; ANIMALS; DOGS; ESTERS; FEMALE; KIDNEY; LIVER; MALE; VITAMIN A;

ANIMALIA; CANIS FAMILIARIS;

EID: 0031827857     PISSN: 03009831     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Ribaya-Mercado, J.D., Blanco, M.C., Fox, J.G. and Russell, R.M. (1994) High concentrations of vitamin A esters circulate primarily as retinyl stearate and are stored primarily as retinyl palmitate in ferret tissues. J. Am. Coll. Nutr. 13, 83-86.
2. Schweigert, F.J. (1988) Insensitivity of dogs to the effects of nonspecific bound vitamin A in plasma. Int. J. Vitam. Nutr. Res. 58, 23-25.
3. Schweigert, F.J., Ryder, O.A., Rambeck, W.A. and Zucker, H. (1990) The majority of vitamin A is transported as retinyl esters in the blood of most carnivores. Comp. Biochem Physiol. A 95, 573-578.
4. Smith, F.R. and Goodman, D.S. (1976) Vitamin A transport in human vitamin A toxicity. N. Engl. J. Med. 294, 805-808.
5. Biesalski, H.K., Hemmes, C., El Hanafy, M., Weiser, H., Zschaebitz, H. and Stofft, E. (1996) Long-term administration of high dose vitamin A to rats does not cause fetal malformations: macroscopic, skeletal and physicochemical findings. J. Nutr. 126, 973-983.
6. Tzimas, G., Thiel, R., Chahoud, I. and Nau, H. (1997) The area under the concentration-time curve of all-trans-retinoic acid is the most suitable pharmacokinetic correlate to the embryotoxicity of this retinoid in the rat. Toxicol. Appl. Pharmacol. 143, 436-444.
7. Schweigen, F.J. and Thomann, E. (1993) Vitamin A und E bei Karnivoren: Transport im Blut und Organverteilung. Mh. Vet. Med. 48, 25-29.
8. Schweigen, F.J., Thomann, E. and Zucker, H. (1991) Vitamin A in the urine of carnivores. Int. J. Vitam. Nutr. Res. 61, 110-113.
9. Kuba, M. and Kolb, E. (1994) Biochemische Analysen an Hunden der Rasse "Beagel": 1. Mitteilung: Der Gehalt an DNA, an RNA und an Protein in 13 Geweben im Alter von einem Tag bis zu 18 Monaten.Dtsch. Tierärztl. Wschr. 101, 71-75.
10. NRC (1985) Nutrient requirements of domestic animals: nutrient requirements of dogs. National Academy of Sciences, National Research Council, Washington D.C.
11. Radin, N.S. (1981) Extraction of tissue lipids with a solvent of low toxicity. Meth. Enzymol. 72, 5-7.
12. Krinsky, N.I., Russett, M.D., Handelman, G.J. and Snodderly, D.M. (1990) Structural and geometrical isomers of carotenoids in human plasma. J. Nutr. 120, 1654-1662.
13. Ross, A.C. (1981) Separation of long-chain fatty acid esters of retinol by high-performance liquid chromatography. Anal. Biochem. 115, 324-330.
14. Hamilton, R. and Carroll, K. (1977) Plasma cholesterol levels in suckling and weaned kittens, puppies, and guinea pigs. Lipids 12, 145-148.
15. Schweigert, F.J., Uehlein-Harrell, S. and Zucker, H. (1990) Effect of feeding on vitamin A concentrations in blood plasma of dogs. Zentralbl. Veterinärmed. A 37, 605-609.
16. Wilson, D.E., Hejazi, J., Elstad, N.L., Chan, I.F., Gleeson, J.M. and Iverius, P.H. (1987) Novel aspects of vitamin A metabolism in the dog: distribution of lipoprotein retinyl esters in vitamin A-deprived and cholesterol-fed animals. Biochim. Biophys. Acta 922, 247-258.
17. Blomhoff, R. (1994) Transport and metabolism of vitamin A. Nutr. Rev. 52, S13-23.
18. Lorente, C. and Miller, S. (1977) Fetal and maternal vitamin A levels in tissues of hypervitaminotic A rats and rabbits. J. Nutr. 107, 1816-1821.
19. Montreewasuwat, N. and Olson, J.A. (1979) Serum and liver concentrations of vitamin A in Thai fetuses as a function of gestational age. Am. J. Clin. Nutr. 32, 601-606.
20. Southcott, R., Chesterfield, N. and Lugg, D. (1971) Vitamin A content of the livers of huskies and some seals from Antarctic and subantarctic regions. Med. J. Aust. 1, 311-313.
21. Batres, R.O. and Olson, J.A. (1987) Relative amount and ester composition of vitamin A in rat hepatocytes as a function of the method of cell preparation and of total liver stores. J. Nutr. 177, 77-82.
22. Futterman, S. and Andrews, J. (1964) The composition of liver vitamin A ester and the synthesis of vitamin A ester by liver microsomes. J. Biol. Chem. 239, 4077-4080.
23. Bhat, P., Lacroix, A. (1983) Separation and estimation of retinyl fatty acyl esters in tissues of normal rat by high-performance liquid chromatography. J. Chromatogr. 272, 269-278.
24. Furr, H. (1990) Reversed-phase high-performance liquid chromatography of retinyl esters. Methods Enzymol. 189, 85-94.
25. Ross, A.C., Davila, M.E. and Cleary, M.P. (1985) Fatty acids and retinyl esters of rat milk: effects of diet and duration of lactation. J. Nutr. 115, 1488-1497.
26. Furr, H.C., Clifford, A.J., Smith, L.M. and Olson, J.A. (1989) The effect of dietary fatty acid composition on liver retinyl ester (vitamin A ester) composition in the rat. J. Nutr. 119, 581-585.