Thrombin regulation of endothelin-1 gene in isolated human pulmonary endothelial cells

Chest

Volumn 114, Issue 1 SUPPL., 1998, Pages 63S-64S

  Golden, C G ^a   Nick, H S ^a   Visner, Gary A ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN 1;

CONFERENCE PAPER; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE CONTROL; GENE DELETION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LUNG ENDOTHELIUM; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION;

EID: 0031827556     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.114.1_Supplement.63S     Document Type: Conference Paper

References (9)

1. Rubanyi GM. Endothelin. New York: Oxford University Press, 1992; 72-102
2. Giaid A, Yanagisawa M, Langleben D, et al. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med 1993; 328:1732-39
3. Lee M, Bloch KD, Clifford JA, et al. Functional analysis of the endothelin-1 gene promoter. J Biol Chem 1990; 265:10446-50
4. Lee M, Dhadly MS, Temizer DH, et al. Regulation of the endothelin-1 gene expression by fos and jun. J Biol Chem 1991; 266:19034-39
5. Wilson DB, Dorfman DM, Orkin SH. A nonerythroid GATA-binding protein is required for function of the human preproendothelin-1 promoter in endothelial cells. Mol Cell Biol 1990; 10:4854-62
6. Benatti L, Bonecchi L, Cozzi L, et al. Two preproendothelin 1 mRNAs transcribed by alternative promoters. J Clin Invest 1993; 91:1149-56
7. Maemura K, Kurihara H, Morita T, et al. Production of endothelin-1 in vascular endothelial cells is regulated by factors associated with vascular injury. Gerontology 1992; 38(suppl 1):29-35
8. Oliver FJ, de la Rubia G, Feener EP, et al. Stimulation of endothelin-1 gene expression by insulin in endothelial cells. J Biol Chem 1991; 266:23251-56
9. Visner GA, Staples ED, Chesrown SE, et al. Isolation and maintenance of human pulmonary artery endothelial cells in culture isolated from transplant donors. Am J Physiol 1994; 267:L406-13