Asynchronous replication of allelic loci in Down syndrome

European Journal of Human Genetics

Volumn 6, Issue 4, 1998, Pages 359-364

  Amiel, Aliza ^a   Avivi, Lydia ^b   Gaber, Elena ^a   Fejgin, Moshe D ^a  

^a MEIR MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Allele specific expression; Asynchronous replication; Down syndrome; FISH; In situ hybridisation; Replication synchrony; Replication timing

Indexed keywords

ALLELE; ARTICLE; CHROMOSOME 21; CONTROLLED STUDY; DNA REPLICATION; DNA SEQUENCE; DOWN SYNDROME; FETUS; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TIME;

EID: 0031827452     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200199     Document Type: Article

References (24)

1. Goldman MA, Holmquist GP, Gray MC, Caston LA, Nag A: Replication timing of mammalian genes and middle repetitive sequences. Science 1984; 224: 686-692.
2. Holmquist GP: Role of replication time in the control of tissue specific gene expression. Am J Hum Genet 1987; 40: 151-173.
3. Hatton KS, Dhar VH, Brown EH et al: Replication program of active and inactive multigene families in mammalian cells. Mol Cell Biol 1988; 8: 2149-2158.
4. Gartler SM, Riggs AD: Mammalian X-chromosome inactivation. Annu Rev Genet 1983; 17: 155-190.
5. Lyon MF: X-chromosome inactivation and the location and expression of X-linked genes. Am J Hum Genet 1988; 42: 8-16.
6. Brown CJ, Willard HF: Moleclar and genetics studies of human X-chromosome inactivation. Adv Dev Biol 1993; 2: 37-72.
7. Latt SA: Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes. Pro Natl Acad Sci USA 1973; 70: 3395-3399.
8. Dutrillaux B, Couturier J, Richer CL, Viegases-Pequignot E: Sequence of DNA replication in 227 R- and Q-bands of human chromosomes using a BrdU treatment. Chromosoma 1976; 58: 51-61.
9. Drouin R, Lemieux N, Richer CL: Analysis of DNA replication during S phase by means of dynamic chromosome banding at high resolution Chromosoma 1990; 99: 273-280.
10. Selig S, Okumura K, Ward DC, Cedar H: Delineation of DNA replication time zones by fluorescence in situ hybridisation. EMBO J 1992; 11: 1217-1225.
11. Kitsberg D, Selig S, Brandeis M et al: Allele-specific replication timing of imprinted gene regions. Nature 1993; 364: 459-163.
12. Boggs BA, Chinault AC: Analysis of replication timing properties of human X-chromosomal loci by fluorescence in situ hybridisation. Proc Natl Acad Sci USA 1994; 91: 6083-6087.
13. Amiel A, Litmanovitch T, Gaber E, Lishner M, Avivi L, Fejgin M: Asynchronous replication of p53 and 21q22 loci in chronic lymphocytic leukemia. Hum Genet 1997; 101: 219-222.
14. Knoll JHM, Cheng SD, Lalande M: Allele specificity of DNA replication timing in the Angelmann/Prader-Willi syndrome imprinted chromosomal region. Nat Genet 1994; 6: 41-46.
15. Gunaratne PH, Nakao M, Ledbetter DH, Sutcliffe JS, Chinault AC: Tissue-specific and allele-specific replication timing control in the imprinted human Prader-Willi syndrome region. Genes & Dev 1995; 9: 808-820.
16. White LM, Rogan PK, Nicholls RD, Wu BL, Korf B, Knoll JHM: Allele specific replication of 15q11-q13 loci: a diagnostic test for uniparental disomy. Am J Hum Genet 1996; 59: 423-430.
17. Chess A, Simon I, Cedar H, Axel R: Allele inactivation regulates olfactory receptor gene expression. Cell 1994; 78: 823-834.
18. Amiel A, Litmanovitch T, Gaber E et al: Asynchrony in replication timing of allelic loci in bone-marrow cells derived from lymphoma and CML patients. Am J Hum Genet 1996; 59 (Suppl): A316.
19. Litmanovitch T: Cytogenetic abnormalities observed in ovarian cancer tumors and in non-malignant cells derived from ovarian cancer patients and first degree relatives. Ph.D. thesis, Tel-Aviv University, 1996.
20. Shen JJ, Williams BJ, Zipursky A et al: Cytogenetic and molecular studies of Down syndrome individuals with leukemia. Am J Hum Genet 1995; 56: 915-925.
21. Hernandez D, Fisher EMC: Down syndrome genetics: unraveling a multifactorial disorder. Hum Mol Genet 1996; 5: 1411-1416.
22. Lichter P, Tang CC, Call K et al: High resolution mapping of human chromosome 11 by in-situ hybridisation with cosmid clones. Science 1990; 247: 64-69.
23. Murray AW, Hunt T: The cell cycle: an introduction. Freeman: New York, 1993.
24. Moulton T, Chung WY, Yuan L et al: Genomic imprinting and Wilms' tumor. Med Pediatr Oncol 1996; 27: 476-483.