-
1
-
-
0025015293
-
Cardiomyopathy of overload. A major determinant of prognosis in congestive heart failure
-
Katz AM. Cardiomyopathy of overload. A major determinant of prognosis in congestive heart failure. N Engl J Med 1990;322:100-10.
-
(1990)
N Engl J Med
, vol.322
, pp. 100-110
-
-
Katz, A.M.1
-
2
-
-
0028934074
-
Future approaches to pharmacologic therapy for congestive heart failure
-
Massie BM, Shah NB. Future approaches to pharmacologic therapy for congestive heart failure. Curr Opin Cardiol 1995;10:229-37.
-
(1995)
Curr Opin Cardiol
, vol.10
, pp. 229-237
-
-
Massie, B.M.1
Shah, N.B.2
-
3
-
-
0028081393
-
Effects of short-and long-term carvedilol administration on rest and exercise hemodynamic variables, exercise capacity and clinical conditions in patients with idiopathic dilated cardiomyopathy
-
Metra M, Nardi M, Giubbini R, Dei-Cas L. Effects of short-and long-term carvedilol administration on rest and exercise hemodynamic variables, exercise capacity and clinical conditions in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol 1994;24:1678-87.
-
(1994)
J Am Coll Cardiol
, vol.24
, pp. 1678-1687
-
-
Metra, M.1
Nardi, M.2
Giubbini, R.3
Dei-Cas, L.4
-
4
-
-
0028947523
-
Carvedilol improves left ventricular function and symptoms in chronic heart failure: A double-blind randomized study
-
Olsen SL, Gilbert EM, Renlund DG, Taylor DO, Yanowitz FD, Bristow MR. Carvedilol improves left ventricular function and symptoms in chronic heart failure: a double-blind randomized study. J Am Coll Cardiol 1995;25:1225-31.
-
(1995)
J Am Coll Cardiol
, vol.25
, pp. 1225-1231
-
-
Olsen, S.L.1
Gilbert, E.M.2
Renlund, D.G.3
Taylor, D.O.4
Yanowitz, F.D.5
Bristow, M.R.6
-
5
-
-
0029006613
-
Effects of carvedilol, a vasodilator-beta-blocker, in patients with congestive heart failure due to ischemic heart disease
-
Australia-New Zealand Heart Failure Research Collaborative Group. Effects of carvedilol, a vasodilator-beta-blocker, in patients with congestive heart failure due to ischemic heart disease. Circulation 1995;92:212-18.
-
(1995)
Circulation
, vol.92
, pp. 212-218
-
-
-
6
-
-
0029085811
-
Double-blind, placebo-controlled study of the long-term efficacy of carvedilol in patients with severe chronic heart failure
-
Krum H, Sackner-Bernstein JD, Goldsmith RL, et al. Double-blind, placebo-controlled study of the long-term efficacy of carvedilol in patients with severe chronic heart failure. Circulation 1995;92:1499-1506.
-
(1995)
Circulation
, vol.92
, pp. 1499-1506
-
-
Krum, H.1
Sackner-Bernstein, J.D.2
Goldsmith, R.L.3
-
7
-
-
10544231452
-
Carvedilol inhibits clinical progression in patients with mild symptoms of heart failure
-
Colucci WS, Packer M, Bristow MR, for the U.S. Carvedilol Heart Failure Study Group. Carvedilol inhibits clinical progression in patients with mild symptoms of heart failure. Circulation 1996;94:2800-6.
-
(1996)
Circulation
, vol.94
, pp. 2800-2806
-
-
Colucci, W.S.1
Packer, M.2
Bristow, M.R.3
-
8
-
-
10544251442
-
Double-blind, placebo-controlled study of the effects of carvedilol in patients with moderate to severe heart failure. The PRECISE trial
-
Packer M, Colucci WS, Sackner-Bernstein JD, for the PRECISE Study Group. Double-blind, placebo-controlled study of the effects of carvedilol in patients with moderate to severe heart failure. The PRECISE trial. Circulation 1996;94:2793-9.
-
(1996)
Circulation
, vol.94
, pp. 2793-2799
-
-
Packer, M.1
Colucci, W.S.2
Sackner-Bernstein, J.D.3
-
9
-
-
10544223267
-
Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure
-
Bristow MR, Gilbert EM, Abraham WT, for the MOCHA Investigators. Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure. Circulation 1996;94:2807-16.
-
(1996)
Circulation
, vol.94
, pp. 2807-2816
-
-
Bristow, M.R.1
Gilbert, E.M.2
Abraham, W.T.3
-
10
-
-
0026785561
-
Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions
-
The SOLVD Investigators. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. N Engl J Med 1992;327:685-91.
-
(1992)
N Engl J Med
, vol.327
, pp. 685-691
-
-
-
11
-
-
0023266532
-
Effects of enalapril on mortality in severe congestive heart failure: Results of the cooperative north Scandinavian enalapril survival study (CONSENSUS)
-
The CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure: results of the cooperative north Scandinavian enalapril survival study (CONSENSUS). N Engl J Med 1987;316:1429-35.
-
(1987)
N Engl J Med
, vol.316
, pp. 1429-1435
-
-
-
12
-
-
0025913812
-
Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
-
The SOLVD Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med 1991;325:293-302.
-
(1991)
N Engl J Med
, vol.325
, pp. 293-302
-
-
-
13
-
-
0024994781
-
β-Adrenergic pathways in nonfailing and failing human ventricular myocardium
-
Bristow MR, Hershberger RE, Port JD, et al. β-Adrenergic pathways in nonfailing and failing human ventricular myocardium. Circulation 1990;82(suppl I):I-12-25.
-
(1990)
Circulation
, vol.82
, Issue.1 SUPPL.
-
-
Bristow, M.R.1
Hershberger, R.E.2
Port, J.D.3
-
14
-
-
16944364094
-
Selective downregulation of the angiotensin II AT1-receptor subtype in failing human ventricular myocardium
-
Asano K, Dutcher DL, Port JD, et al. Selective downregulation of the angiotensin II AT1-receptor subtype in failing human ventricular myocardium. Circulation 1997;95:1193-2000.
-
(1997)
Circulation
, vol.95
, pp. 1193-2000
-
-
Asano, K.1
Dutcher, D.L.2
Port, J.D.3
-
15
-
-
0019982539
-
Decreased catecholamine sensitivity and β-adrenergic receptor density in failing human heart
-
Bristow MR, Ginsburg R, Minobe WA, et al. Decreased catecholamine sensitivity and β-adrenergic receptor density in failing human heart. N Engl J Med 1982;307:205-11.
-
(1982)
N Engl J Med
, vol.307
, pp. 205-211
-
-
Bristow, M.R.1
Ginsburg, R.2
Minobe, W.A.3
-
16
-
-
0026558346
-
Adrenergic effects on the biology of the adult mammalian cardiocyte
-
Mann DL, Kent RL, Parsons B, Cooper G IV. Adrenergic effects on the biology of the adult mammalian cardiocyte. Circulation 1992;85:790-804.
-
(1992)
Circulation
, vol.85
, pp. 790-804
-
-
Mann, D.L.1
Kent, R.L.2
Parsons, B.3
Cooper IV, G.4
-
17
-
-
0018950340
-
Beneficial effects of long-term beta-blockade in congestive cardiomyopathy
-
Swedberg K, Hjalmarson A, Waagstein F, Wallentin I. Beneficial effects of long-term beta-blockade in congestive cardiomyopathy. Br Heart J 1980;44:117-33.
-
(1980)
Br Heart J
, vol.44
, pp. 117-133
-
-
Swedberg, K.1
Hjalmarson, A.2
Waagstein, F.3
Wallentin, I.4
-
18
-
-
0025339446
-
Pharmacological characteristics of the stereoisomers of carvedilol
-
Bartsch W, Sponer G, Stren K, et al. Pharmacological characteristics of the stereoisomers of carvedilol. Eur J Clin Pharmacol 1990;38(suppl 2):S104-7.
-
(1990)
Eur J Clin Pharmacol
, vol.38
, Issue.2 SUPPL.
-
-
Bartsch, W.1
Sponer, G.2
Stren, K.3
-
19
-
-
0025372087
-
The pharmacology of carvedilol
-
Ruffolo RR Jr, Gelai M, Heible JP, Willette RN. Nichols AJ. The pharmacology of carvedilol. Eur J Clin Pharmacol 1990;38(suppl 2):S23-32.
-
(1990)
Eur J Clin Pharmacol
, vol.38
, Issue.2 SUPPL.
-
-
Ruffolo Jr., R.R.1
Gelai, M.2
Heible, J.P.3
Willette, R.N.4
Nichols, A.J.5
-
20
-
-
0026551970
-
Effects of carvedilol on adrenergic receptor pharmacology in human ventricular myocardium and lymphocytes
-
Bristow MR, Larrabee P, Muller-Beckmann B, et al. Effects of carvedilol on adrenergic receptor pharmacology in human ventricular myocardium and lymphocytes. Clin Invest 1992;70:S105-13.
-
(1992)
Clin Invest
, vol.70
-
-
Bristow, M.R.1
Larrabee, P.2
Muller-Beckmann, B.3
-
21
-
-
85047235810
-
The effects of intravenous carvedilol, a new multiple action vasodilating β-blocker, in congestive heart failure
-
Das Gupta P, Broadhurst P, Lahiri A. The effects of intravenous carvedilol, a new multiple action vasodilating β-blocker, in congestive heart failure. J Cardiovasc Pharmacol 1991;18(suppl 4):S12-16.
-
(1991)
J Cardiovasc Pharmacol
, vol.18
, Issue.4 SUPPL.
-
-
Das Gupta, P.1
Broadhurst, P.2
Lahiri, A.3
-
22
-
-
0029919877
-
Cardiac adrenergic receptor effects of carvedilol
-
Yoshikawa T, Port JD, Asano K, et al. Cardiac adrenergic receptor effects of carvedilol. Eur Heart J 1996;17(suppl 11):S81-4.
-
(1996)
Eur Heart J
, vol.17
, Issue.11 SUPPL.
-
-
Yoshikawa, T.1
Port, J.D.2
Asano, K.3
-
23
-
-
0026694066
-
Receptor pharmacology of carvedilol in the human heart
-
Bristow MR, Larrabee P, Minobe W, et al. Receptor pharmacology of carvedilol in the human heart. J Cardiovasc Pharmacol 1992;19(suppl 1):S68-80.
-
(1992)
J Cardiovasc Pharmacol
, vol.19
, Issue.1 SUPPL.
-
-
Bristow, M.R.1
Larrabee, P.2
Minobe, W.3
-
24
-
-
0029845423
-
Comparative hemodynamic and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in the failing human heart
-
Gilbert EM, Abraham WT, Olsen S, et al. Comparative hemodynamic and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in the failing human heart. Circulation 1996;94:2817-25.
-
(1996)
Circulation
, vol.94
, pp. 2817-2825
-
-
Gilbert, E.M.1
Abraham, W.T.2
Olsen, S.3
-
25
-
-
0028209348
-
Negative antagonists promote an inactive conformation of the β-adrenergic receptor
-
Samama P, Pei G, Costa T, Cotecchia S, Lefkowitz RJ. Negative antagonists promote an inactive conformation of the β-adrenergic receptor. Mol Pharmacol 1994;45:390-4.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 390-394
-
-
Samama, P.1
Pei, G.2
Costa, T.3
Cotecchia, S.4
Lefkowitz, R.J.5
-
27
-
-
0028350901
-
Inverse agonist activity of β-adrenergic antagonists
-
Chidiac P, Hebert TE, Valiquette M, Dennis M, Bouvier M. Inverse agonist activity of β-adrenergic antagonists. Mol Pharmacol 1994;45:490-9.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 490-499
-
-
Chidiac, P.1
Hebert, T.E.2
Valiquette, M.3
Dennis, M.4
Bouvier, M.5
-
28
-
-
0003435389
-
Clinical relevance of inverse agonism and quanine nucleotide modulatable binding properties of β-adrenergic receptor blocking agents
-
Lowes BD, Chidiac P, Olsen S, et al. Clinical relevance of inverse agonism and quanine nucleotide modulatable binding properties of β-adrenergic receptor blocking agents. Circulation 1994;90:1-543.
-
(1994)
Circulation
, vol.90
, pp. 1-543
-
-
Lowes, B.D.1
Chidiac, P.2
Olsen, S.3
-
29
-
-
0025602392
-
Experimental and clinical pharmacology of carvedilol and other drugs combining vasodilation and beta-adrenoceptor antagonism in a single molecule
-
Strein K, Sponer G. Experimental and clinical pharmacology of carvedilol and other drugs combining vasodilation and beta-adrenoceptor antagonism in a single molecule. Z-Kardiol 1990;79(suppl 3):89-98.
-
(1990)
Z-Kardiol
, vol.79
, Issue.3 SUPPL.
, pp. 89-98
-
-
Strein, K.1
Sponer, G.2
-
30
-
-
0026779879
-
Carvedilol, a new vasodilator and beta adrenoceptor antagonist is an antioxidant and free radical scavenger
-
Yue T-L, Cheng H-Y, Lysko PG, et al. Carvedilol, a new vasodilator and beta adrenoceptor antagonist is an antioxidant and free radical scavenger. J Pharmacol Exp Ther 1992;263:92-8.
-
(1992)
J Pharmacol Exp Ther
, vol.263
, pp. 92-98
-
-
Yue, T.-L.1
Cheng, H.-Y.2
Lysko, P.G.3
-
31
-
-
0026462553
-
Carvedilol, a new antihypertensive prevents oxidation of human low density lipoprotein by macrophages and copper
-
Yue T-L, McKenna PJ, Lysko PG, Ruffolo RR Jr, Feuerstein GZ. Carvedilol, a new antihypertensive prevents oxidation of human low density lipoprotein by macrophages and copper. Atherosclerosis 1992;97:209-16.
-
(1992)
Atherosclerosis
, vol.97
, pp. 209-216
-
-
Yue, T.-L.1
McKenna, P.J.2
Lysko, P.G.3
Ruffolo Jr., R.R.4
Feuerstein, G.Z.5
-
32
-
-
0026533584
-
Carvedilol, a new β-adrenergic antagonist and vasodilator antihypertensive drug, inhibits Superoxide release from human neutrophils
-
Yue-T-L, McKenna PJ, Ruffolo RR Jr, Feuerstein GZ. Carvedilol, a new β-adrenergic antagonist and vasodilator antihypertensive drug, inhibits Superoxide release from human neutrophils. Eur J Pharmacol 1992;214:277-80.
-
(1992)
Eur J Pharmacol
, vol.214
, pp. 277-280
-
-
Yue, T.-L.1
McKenna, P.J.2
Ruffolo Jr., R.R.3
Feuerstein, G.Z.4
-
33
-
-
0029873049
-
Carvedilol, a novel vasodilating beta-blocker with the potential for cardiovascular organ protection
-
Feuerstein GZ, Ruffolo RR Jr. Carvedilol, a novel vasodilating beta-blocker with the potential for cardiovascular organ protection. Eur Heart J 1996;17(suppl B):24-9.
-
(1996)
Eur Heart J
, vol.17
, Issue.SUPPL. B
, pp. 24-29
-
-
Feuerstein, G.Z.1
Ruffolo Jr., R.R.2
-
34
-
-
0027163945
-
Carvedilol, a cardiovascular drug, prevents smooth muscle proliferation, migration, and neointimal formation following vascular injury
-
Ohlstein EH, Douglas SA, Sung C-P, et al Carvedilol, a cardiovascular drug, prevents smooth muscle proliferation, migration, and neointimal formation following vascular injury. Proc Natl Acad Sci USA 1993;90:6189-93.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6189-6193
-
-
Ohlstein, E.H.1
Douglas, S.A.2
Sung, C.-P.3
-
35
-
-
0023571649
-
Pharmacokinetics and bioavailability of carvedilol, a vasodilating beta-blocker
-
von Mollendorff E, Reiff K, Neugebauer G. Pharmacokinetics and bioavailability of carvedilol, a vasodilating beta-blocker. Eur J Clin Pharmacol 1987;33:511-13.
-
(1987)
Eur J Clin Pharmacol
, vol.33
, pp. 511-513
-
-
Von Mollendorff, E.1
Reiff, K.2
Neugebauer, G.3
-
36
-
-
0025300364
-
Stereoselective disposition of carvedilol in man after intravenous and oral administration of the racemic compound
-
Neugebauer G, Akpan W, Kaufmann B, Reiff K. Stereoselective disposition of carvedilol in man after intravenous and oral administration of the racemic compound. Eur J Clin Pharmacol 1990;38:S108-11.
-
(1990)
Eur J Clin Pharmacol
, vol.38
-
-
Neugebauer, G.1
Akpan, W.2
Kaufmann, B.3
Reiff, K.4
-
37
-
-
0022896586
-
Liquid Chromatographic assay and disposition of carvedilol in healthy volunteers
-
Varin F, Cubeddu LX, Powell JF. Liquid Chromatographic assay and disposition of carvedilol in healthy volunteers. J Pharmaceut Sci 1986;75:1195-7.
-
(1986)
J Pharmaceut Sci
, vol.75
, pp. 1195-1197
-
-
Varin, F.1
Cubeddu, L.X.2
Powell, J.F.3
-
38
-
-
0025372785
-
Assay and disposition of carvedilol enantiomers in humans and monkeys: Evidence of Stereoselective pressystemic metabolism
-
Fujimaki M, Halusui H, Haseqawa H. Assay and disposition of carvedilol enantiomers in humans and monkeys: evidence of Stereoselective pressystemic metabolism. J Pharmaceut Sci 1990;79:568-72.
-
(1990)
J Pharmaceut Sci
, vol.79
, pp. 568-572
-
-
Fujimaki, M.1
Halusui, H.2
Haseqawa, H.3
-
39
-
-
2642612855
-
-
Philadelphia
-
SmithKline Beecham Pharmaceuticals, Clinical Research and Development. Investigator brochure: carvedilol. Philadelphia;1995.
-
(1995)
Investigator Brochure: Carvedilol
-
-
-
40
-
-
0029937949
-
The effect of carvedilol on morbidity and mortality in patients with chronic heart failure
-
Packer M, Bristow MR, Cohn JN, for the U.S. Carvedilol Heart Failure Study Group. The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. N Engl J Med 1996;334:1349-55.
-
(1996)
N Engl J Med
, vol.334
, pp. 1349-1355
-
-
Packer, M.1
Bristow, M.R.2
Cohn, J.N.3
-
41
-
-
0000987062
-
Safety and efficacy of carvedilol in severe heart failure
-
Cohn JN, Fowler MR, Bristow MR, et al. Safety and efficacy of carvedilol in severe heart failure [abstr]. J Am Coll Cardiol 1996;27(suppl A):169A.
-
(1996)
J Am Coll Cardiol
, vol.27
, Issue.SUPPL. A
-
-
Cohn, J.N.1
Fowler, M.R.2
Bristow, M.R.3
-
42
-
-
0005062568
-
Carvedilol without ACE inhibition in the treatment of patients with moderate to severe heart failure
-
Gilbert EM, Colucci WS, Fowler MB, for th U.S. Carvedilol Heart Failure Study Group. Carvedilol without ACE inhibition in the treatment of patients with moderate to severe heart failure [abstr]. Circulation 1996;94(suppl I):I-663.
-
(1996)
Circulation
, vol.94
, Issue.1 SUPPL.
-
-
Gilbert, E.M.1
Colucci, W.S.2
Fowler, M.B.3
-
43
-
-
0038767228
-
Augmented digoxin concentrations with carvedilol in mild-moderate heart failure
-
Grunden JW, Gilbert EM, Munger MA. Augmented digoxin concentrations with carvedilol in mild-moderate heart failure. Am J Ther 1994;1:157-61.
-
(1994)
Am J Ther
, vol.1
, pp. 157-161
-
-
Grunden, J.W.1
Gilbert, E.M.2
Munger, M.A.3
-
44
-
-
0030999932
-
Practical guidelines for initiation of beta-adrenergic blockade in patients with chronic heart failure
-
Eichhorn EJ, Bristow MR. Practical guidelines for initiation of beta-adrenergic blockade in patients with chronic heart failure. Am J Cardiol 1997;79:794-8.
-
(1997)
Am J Cardiol
, vol.79
, pp. 794-798
-
-
Eichhorn, E.J.1
Bristow, M.R.2
-
45
-
-
0000280376
-
Should worsening heart failure early after initiation of beta-blocker therapy for chronic heart failure preclude long-term benefit?
-
Sackner-Bernstein J, Krum H, et al. Should worsening heart failure early after initiation of beta-blocker therapy for chronic heart failure preclude long-term benefit? [abstr]. Circulation 1995;92(suppl I):I-395.
-
(1995)
Circulation
, vol.92
, Issue.1 SUPPL.
-
-
Sackner-Bernstein, J.1
Krum, H.2
|