Increased interleukin-4 and interleukin-5 production in response to Schistosoma haematobium adult worm antigens correlates with lack of reinfection after treatment

Journal of Infectious Diseases

Volumn 178, Issue 2, 1998, Pages 512-519

  Medhat, Ahmed ^b   Shehata, Magda ^b   Bucci, Kim ^b   Mohamed, Shoari ^b   Dief, Ahmed Diab Enas ^b   Badary, Saad ^b   Galal, Hesham ^b   Nafeh, Mohamed ^b   King, Christopher L ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4; INTERLEUKIN 5;

ADOLESCENT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HOST RESISTANCE; HUMAN; IMMUNOREACTIVITY; LYMPHOCYTE CULTURE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REINFECTION; SCHISTOSOMA HEMATOBIUM; SCHISTOSOMIASIS;

EID: 0031825621     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/515630     Document Type: Article

References (25)

1. Butterworth A. Immunity in human schistosomiasis. Acta Trop Suppl 1987;12:31-40.
2. Wilkins H, Blumenthal U, Hagan P, Hayes R, Tulloch S. Resistance to reinfection after treatment of urinary schistosomiasis. Trans R Soc Trop MedHyg 1987;81:29-35.
3. Hagan P, Blumenthal U, Dunn D, Simpson A, Wilkins H. Human IgE, IgG4 and resistance to reinfection with Schistosoma haematobium. Nature 1991;349:243-5.
4. Dunne DW, Butterworth AE, Fulford AJC, et al. Immunity after treatment of human schistosomiasis: association between IgE antibodies to adult worm antigens and resistance to reinfection. Eur J Immunol 1992;22: 1483-94.
5. Rihet P, Demeure CE, Bourgois A, Praia A, Dessein AJ. Evidence for an association between human resistance to Schistosoma mansoni and high anti-larval IgE levels. Eur J Immunol 1991;21:2679-86.
6. Grzych JM, Grezel D, Xu CB, et al. IgA antibodies to a protective antigen in human schistosomiasis mansoni. J Immunol 1993;150:527-35.
7. Sturrock R, Kimani R, Cottrell B, et al. Observations on possible immunity to reinfection among Kenyan schoolchildren after treatment for Schistosoma mansoni. Trans R Soc Trop Med Hyg 1983;77:363-71.
8. Hagan P, Wilkins H, Blumenthal U, Hayes R, Greenwood B. Eosinophilia and resistance to Schistosoma haematobium in man. Parasite Immunol 1985;7:625-32.
9. Demeure C, Rihet P, Abel L, Ouattara M, Bourgois A, Dessein A. Resistance to Schistosoma mansoni in humans: influence of the IgE/IgG4 balance and IgG2 in immunity to reinfection after chemotherapy. J Infect Dis 1993;168:1000-8.
10. Dunne DW, Grabowska AM, Fulford AJ, et al. Human antibody responses to Schistosoma mansoni: the influence of epitopes shared between different life-cycle stages on the response to the schistosomulum. Eur J Immunol 1988;18:123-31.
11. King CL, Xianli J, Malhotra I, Liu S, Mahmoud A, Oettgen H. Mice with a targeted deletion of the IgE gene have increased worm burdens and reduced granulomatous inflammation following primary infection with Schistosoma mansoni. J Immunol 1997;158:294-300.
12. Roberts M, Butterworth A, Kimani G, et al. Immunity after treatment of human schistosomiasis: association between cellular responses and resistance to reinfection. Infect Immun 1993;61:4984-93.
13. Couissinier-Paris P, Dessein A. Schistosoma-specific helper T cell clones from subjects resistant to infection by Schistosoma mansoni are Th0/2. Eur J Immunol 1995;25:2295-302.
14. Marquet S, Abel L, Hillaire D, et al. Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33. Nat Genet 1996;14:181-4.
15. Marsh D. Linkage analysis of IL-4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 1994;264: 1152-6.
16. Butterworth AE, Dalton PR, Dunne DW, et al. Immunity after treatment of human schistosomiasis mansoni. I. Study design, pretreatment observations and the results of treatment. Trans R Soc Trop Med Hyg 1984; 78:108-23.
17. Hagan P, Blumenthal U, Chaudri M, et al. Resistance to reinfection with Schistosoma haematobium in Gambian children: analysis of their immune responses. Trans R Soc Trop Med Hyg 1987;81:938-46.
18. Wilkins H, Goll P, Marshall T, Moore P. Dynamics of Schistosoma haematobium infection in a Gambian community. I. The pattern of human infection in the study area. Trans R Soc Trop Med Hyg 1984;78:216-21.
19. Smith JH, Elwi A, Kamel IA, von Lichtenberg F. A quantitative post mortem analysis of urinary schistosomiasis in Egypt. II. Evolution and epidemiology. Am J Trop Med Hyg 1975;24:806-22.
20. King C, Keating C, Muruka J, et al. Urinary tract morbidity in schistosomiasis haematobia: associations with age and intensity of infection in an endemic area of Coast Province, Kenya. Am J Trop Med Hyg 1988; 39:361-8.
21. Kloos H, Higashi G, Schlinski V, Mansour N, Murrell K, Miller F. Water contact and Schistosoma haematobium infection: a case study from an Upper Egyptian Village. Int J Epidemiol 1990;19:749-57.
22. Fulford A, Ouma J, Kariuki H, et al. Water contact observations in Kenyan communities endemic for schistosomiasis: methodology and patterns of behaviour. Parasitology 1996;113:223-41.
23. Boros DV, Warren KS. Delayed hypersensitivity-type granuloma formation and dermal reaction induced and elicited by a soluble factor isolated from Schistosoma mansoni eggs. J Exp Med 1970;132:488-507.
24. de Waal Malefyt R, Haanen J, Spits H, et al. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via down-regulation of class II major histocompatibility complex expression. J Exp Med 1991;174:915-24.
25. Mahanty S, Abrams JS, King CL, Limaye AP, Nutman TB. Parallel regulation of IL-4 and IL-5 in human helminth infections. J Immunol 1992; 148:3567-71.