Synthesis, DNA binding, topoisomerase II inhibition and cytotoxicity of two guanidine-containing anthracene-9,10-diones

Anti-Cancer Drug Design

Volumn 13, Issue 5, 1998, Pages 407-415

  Routier, Sylvain ^c   Bernier, Jean Luc ^c   Catteau, Jean Pierre ^c   Riou, Jean François ^a   Bailly, Christian ^b  

^a SANOFI   (France)

^b CENTRE OSCAR LAMBRET   (France)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMETANTRONE; ANTHRAQUINONE DERIVATIVE; ANTINEOPLASTIC AGENT; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); GUANIDINE; GYRASE INHIBITOR; HYDROXYL GROUP; MITOXANTRONE; POLYNUCLEOTIDE; SR 103; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CARCINOMA CELL; CONTROLLED STUDY; DENATURATION; DNA CLEAVAGE; DNA FOOTPRINTING; DNA PROTEIN COMPLEX; DNA SEQUENCE; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTHRAQUINONES; ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CHEMISTRY, PHYSICAL; DEOXYRIBONUCLEASE I; DNA; DNA FOOTPRINTING; DNA TOPOISOMERASES, TYPE II; ENZYME INHIBITORS; GUANIDINES; HEAT; HUMANS; KB CELLS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID DENATURATION;

EID: 0031824488     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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