Evaluation of the developmental toxicity of caffeine and caffeine metabolites using the Frog Embryo Teratogenesis Assay - Xenopus (FETAX)

Food and Chemical Toxicology

Volumn 36, Issue 7, 1998, Pages 591-600

  Fort, D J ^a   Stover, E L ^a   Propst, T L ^a   Faulkner, B C ^a   Vollmuth, T A ^b   Murray, F J ^c  

^a Stover Group   (United States)

^b PEPSICO INC   (United States)

^c Murray and Associates   (United States)

Author keywords

Caffeine; Developmental toxicity; FETAX; Metabolites; Methylxanthines; Xenopus

Indexed keywords

ADENOSINE RECEPTOR BLOCKING AGENT; CAFFEINE; CAFFEINE DERIVATIVE; ISOBUTYLMETHYLXANTHINE; METHYLXANTHINE; PHOSPHODIESTERASE INHIBITOR; THEOPHYLLINE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENZYME INHIBITION; NONHUMAN; TERATOGENICITY; TOXICITY TESTING; TOXICOKINETICS; XENOPUS;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; BIOTRANSFORMATION; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; EMBRYO, NONMAMMALIAN; FEMALE; MALE; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY; XENOPUS;

ANIMALIA; ANURA; XENOPUS LAEVIS;

EID: 0031821338     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(98)00021-0     Document Type: Article

References (21)

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