Elevated adhesiveness/aggregation of peripheral blood leukocytes in patients with major depression

Journal of Affective Disorders

Volumn 50, Issue 1, 1998, Pages 3-9

  Zemishlany, Zvi ^a   Aizenberg, Dov ^a   Klein, Cynthia ^a   Modai, Ilan ^a   Aronson, Moshe ^b   Weizman, Abraham ^a,c  

^a GEHA MENTAL HEALTH CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c RABIN MEDICAL CENTER   (Israel)

Author keywords

Antidepressants; Leukocyte adhesiveness aggregation; Major depression

Indexed keywords

ANTIDEPRESSANT AGENT;

ADULT; ARTICLE; CELL INTERACTION; CELL MIGRATION; DEPRESSION; DOPAMINERGIC TRANSMISSION; ENDOTHELIUM CELL; FEMALE; GRANULOCYTE; HUMAN; LEUKOCYTE ADHERENCE; LEUKOCYTE AGGREGATION; MAJOR CLINICAL STUDY; MALE; MEDIATOR RELEASE; NEUROTRANSMITTER RELEASE; PRIORITY JOURNAL; SYMPATHETIC TONE;

ADULT; ANTIDEPRESSIVE AGENTS; CELL ADHESION; CELL AGGREGATION; DEPRESSIVE DISORDER; FEMALE; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED;

EID: 0031821003     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0327(98)00036-6     Document Type: Article

References (31)

1. Arber N., Berliner S., Rotenberg Z., Friedman J., Belagodatni E., Ostfeld I., Aronson M., Pinkhas J. Detection of aggregated leukocytes in the circulating pool during stress - demargination is not necessarily a result of decreased leukocyte adhesiveness. Acta Haematol. 86:1991;20-24.
2. Arber N., Berliner S., Arber L., Lipshitz A., Sinai Y., Zajicek G., Eilat Y., Pinkhas J., Aronson M. The state of leukocyte adhesiveness/aggregation in the peripheral blood is more sensitive than the white blood cell count for the detection of acute mental stress. J. Psychosom. Res. 36:1992;37-46.
3. Arber N., Liberman E., Vered Y., Fink G., Marom E., Sinai Y., Shiber A., Aronson M., Berliner S. Catecholamine-associated changes in the state of leukocyte adhesiveness/aggregation in the peripheral blood. Stress Med. 9:1993;75-82.
4. Berliner S., Abramovitz M., Kariv N., Weinberger A., Yaron M., Lavie G., Pinkhas J., Aronson M. The leukergy test in rheumatic diseases. New implications for an old test. Ann. Rheum. Dis. 38:1985;899-903.
5. Berliner S., Sclarovsky S., Lavie G., Pinkhas J., Aronson M., Agmon J. The leukergy test in patients with ischemic heart disease. Am. Heart J. 111:1986;9-22.
6. Berliner S., Fishelson Z., Bruhis S., Kaufman H., Pinkhas J., Aronson M. The phenomenon of leukergy: induction and detection of leukocyte aggregation in whole human blood. J. Lab. Clin. Med. 109:1987;575-582.
7. Berliner S., Aronson M. The phenomenon of leukergy (leukocyte adhesiveness/aggregation): a powerful investigative tool and a sensitive indicator of inflammation, trauma and stress. Isr. J. Med. Sci. 27:1991;164-172.
8. Endicott J., Spitzer R.L. A diagnostic interview: the schedule for affective disorders and schizophrenia. Arch. Gen. Psychiatry. 35:1978;837-844.
9. Fleck L. Recent investigations on leukergy. Tex. Rep. Biol. Med. 14:1956;424-431.
10. Frasure-Smith N., Lesperance F., Talajic M. Depression following myocardial infarction. J. Am. Med. Assoc. 270:1993;1819-1825.
11. Grau A.J., Buggle F., Heindle S., Steichen-Wiehn C., Banerjee T., Maiwald M., Rohlfs M., Suhr H., Fiehn W., Becher H., Hacke W. Recent infection as a risk-factor for cerebrovascular ischemia. Stroke. 26:1995;373-379.
12. Green, A.I., Mooney, J.J., Posner, J.A., Schildkraut, J.J., 1995. Mood disorders: biochemical aspects. In: Kaplan, H.I., Sadock, B.J. (Eds), Comprehensive Textbook of Psychiatry VI. Williams and Wilkins, Baltimore, pp. 1089-1102.
13. Halper J.P., Brown R.P., Sweeney J.A., Kocsis J.H., Peters A., Mann J.J. Blunted β-adrenergic responsivity of peripheral blood mononuclear cells in endogenous depression. Isoproterenol dose-response studies. Arch. Gen. Psychiatry. 45:1988;241-244.
14. Hamilton M. A rating scale for depression. J. Neurol. Neurosurg. Psychiatry. 23:1960;56-62.
15. Hammerschmidt D.E., Jeanneret C., Husak M., Lobell M., Jacob H.S. Lymphocytic aggregation in response to adrenergic stimulation. Blood. 71:1988;1470-1474.
16. Harlan J.M. Leukocyte-endothelial interactions. Blood. 65:1985;513-525.
17. Kasperlik A. Leukergy in drug allergy. Bull. Pol. Med. Sci. Hist. 4:1961;20-21.
18. Ladwig K.H., Kieser M., Konig J., Breithardt G., Borggrefe M. Affective disorders and survival after acute myocardial infarction: results from the post infarction late potential study. Eur. Heart J. 12:1991;959-964.
19. Lentnek A.L., Schreiber A.D., MacGregor R.R. The induction of augmented granulocyte adherence by inflammation. J. Clin. Invest. 57:1976;1098-1103.
20. Morris P.L., Robinson R.G., Samuels J. Depression, introversion and mortality following stroke. Aust. N.Z. J. Psychiatry. 27:1993;443-449.
21. Morris P.L.P., Robinson R.G., Andrzejewski P., Samuels J., Price T.R. Association of depression with 10-year poststroke mortality. Am. J. Psychiatry. 150:1993;124-129.
22. Murphy E., Smith R., Lindesay J., Slattery J. Increased mortality rates in late-life depression. Br. J. Psychiatry. 152:1988;347-353.
23. Murphy J.M., Monson R.R., Olivier D.C., Sobol A.M., Leighton A.H. Affective disorders and mortality: a general population study. Arch. Gen. Psychiatry. 44:1987;473-480.
24. Potter W.Z. Psychotherapeutic drugs and biogenic amines: current concepts and therapeutic implications. Drugs. 28:1984;127-143.
25. Rabins P.V., Harvis K., Koven S. High fatality rates of late-life depression associated with cardiovascular disease. J. Affect. Disord. 9:1985;165-167.
26. Rudorfer M.V., Ross R.J., Linnoila M., Sherer M.A., Potter W.Z. Exaggerated orthostatic responsivity of plasma norepinephrine in depression. Arch. Gen. Psychiatry. 42:1985;1186-1192.
27. Shirin H., Pomeranz M., Liberman E., Kedem P., Bartoov M., Arber N., Baruch Y., Arber L., Hirschfeld Z., Pikhas J., Aronson M., Berliner S. Differentiation between major and milder acute mental stress by means of the leukocyte adhesiveness/aggregation test. Behav. Med. 19:1994;175-180.
28. Silvestrini M., Pietroiusti A., Magrini A., Matteis M., Carta S., Bernardi G., Galante A. Leukocyte aggregation in patients with a previous cerebral ischemic event. Stroke. 25:1994;1390-1392.
29. Syrjänen J., Valtonen V.V., Iivaninen M., Kaste M., Huttunen J.K. Preceding infection as an important risk factor for ischaemic brain infarction in young and middle aged patients. Br. Med. J. 296:1988;1156-1160.
30. Youdim M.B.H., Hefez A., Oppenheim B. Human platelet function as a model investigating the clinical efficiency of chlorpromazine. Br. J. Clin. Pharmacol. 12:1981;535-542.
31. Zemishlany Z., Aizenberg D., Baruch Y., Aronson M. Leukocyte adhesiveness/aggregation and neuroleptic drug treatment. Int. Clin. Psychopharmacol. 6:1991;111-116.