Increase of intracellular ph in p53-dependent apoptosis of thymocytes induced by gamma radiation

Radiation Research

Volumn 150, Issue 2, 1998, Pages 183-189

  Dai, H Y ^a   Tsao, N ^a   Leung, W C ^a   Lei, H Y ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

3,4,5 TRIMETHOXYBENZOIC ACID 8 (DIETHYLAMINO)OCTYL ESTER; CYCLOHEXIMIDE; DACTINOMYCIN; PROTEIN P53;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL PH; GAMMA RADIATION; GENE INDUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TARGET CELL DESTRUCTION; THYMOCYTE; TUMOR SUPPRESSOR GENE;

ANIMALS; APOPTOSIS; CALCIUM; CYCLOHEXIMIDE; DACTINOMYCIN; GAMMA RAYS; HYDROGEN-ION CONCENTRATION; MICE; T-LYMPHOCYTES; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0031820404     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579853     Document Type: Article

References (45)

1. A. H. Wyllie, Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284, 555-556 (1980).
2. J. J. Cohen and R. C. Duke, Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J. Immunol. 132, 38-42 (1984).
3. L. M. Zheng, A. Zychlinsky, C. C. Lui, D. M. Ojcius and J. D. E. Young, Extracellular ATP as a trigger for apoptosis or programmed cell death. J. Cell Biol. 112, 279-288 (1991).
4. S. Durant, F. Homo and D. Duval, Calcium and A23187-induced cytolysis of mouse thymocytes. Biochem. Biophys. Res. Commun. 93, 385-391 (1980).
5. C. A. Smith, G. T. Williams, R. Kingston, E. J. Jenkinson and J. J. T. Owen, Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures. Nature 337, 181-184 (1989).
6. T. Hernandez-Caselles and O. Stutman, Immune functions of tumor necrosis factor. I. Tumor necrosis factor induces apoptosis of mouse thymocytes and can also stimulate or inhibit IL-6-induced proliferation depending on the concentration of mitogenic costimulation. J. Immunol. 151, 3999-4012 (1993).
7. R. J. Rotello, R. C. Lieberman, A. F. Purchio and L. E. Gerschenson, Coordinated regulation of apoptosis and cell proliferation by TGF-β1 in cultured cells. Proc. Natl. Acad. Sci. USA 88, 3412-3415 (1991).
8. D. J. McConkey, S. Orrenius and M. Jondal, Agents that elevate cAMP stimulate DNA fragmentation in thymocytes. J. Immunol. 145, 1227-1230 (1990).
9. M. Skalka, J. Matyasova and M. Cejkova, DNA in chromatin of irradiated lymphoid tissues degrades in vivo into regular fragments. FEBS Lett. 72, 271-274 (1976).
10. S. W. Lowe, E. M. Schmitt, S. W. Smith, B. A. Osborne and T. Jacks, p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362, 847-849 (1993).
11. A. R. Clarke, C. A. Purdie, D. J. Harrison, R. G. Morris, C. C. Bird, M. L. Hooper and A. H. Wyllie, Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362, 849-852 (1993).
12. D. Perez-Sala, D. Collado-Escobar and F. Mollinedo, Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease. J. Biol. Chem. 270, 6235-6242 (1995).
13. 2+ and pH. Biochem. Biophys. Res. Commun. 186, 782-789 (1992).
14. M. A. Barry, R. E. Reynolds and A. Eastman, Etoposide-induced apoptosis in human HL-60 cells is associated with intracellular acidification. Cancer Res. 53, 2349-2357 (1993).
15. G. W. Meisenholder, S. J. Martin, D. R. Green, J. Nordberg, B. M. Babior and R. A. Gottlieb, Events in apoptosis: Acidification is downstream of protease activation and BCL-2 protection. J. Biol. Chem. 271, 16260-16262 (1996).
16. D. Shiokawa, H. Ohyama, T. Yamada, K. Takahashi and S. Tanuma, Identification of an endonuclease responsible for apoptosis in rat thymocytes. Eur. J. Biochem. 226, 23-30 (1994).
17. D. Shiokawa, K. Nishimura, H. Maruta and S. Tanuma, DNA fragmentation during thymic apoptosis is catalyzed by DNase γ. Apoptosis 1, 147-152 (1996).
18. 2- exchanger in spontaneous thymocyte apoptosis. J. Immunol. 157, 1107-1116 (1996).
19. H. Y. Lei, M. J. Tong and N. Tsao, Intracellular alkalinization in dexamethasone-induced thymocyte apoptosis. Apoptosis 2, 304-312 (1997).
20. I. Nicoletti, G. Migliorati, M. C. Pagliacci, F. Grignani and C. Riccardi, A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Meth. 139, 271-279 (1991).
21. D. A. Mower, D. W. Peckham, V. A. Illera, J. K. Fishbaugh, L. L. Stunz and R. F. Ashman, Decreased membrane phospholipid packing and decreased cell size precede DNA cleavage in mature mouse B cell apoptosis. J. Immunol. 152, 4832-4842 (1994).
22. E. Musgrove, C. Rugg and D. Hedley, Flow cytometric measurement of cytoplasmic pH: A critical evaluation of available fluorochromes. Cytometry 7, 347-355 (1986).
23. I. R. Radford, Evidence for a general relationship between the individual level of DNA double-strand breakage and cell-killing after x-irradiation of mammalian cells. Int. J. Radiat Biol. 49, 611-620 (1986).
24. G. G. Steel, T. J. McMillan and J. H. Peacock, The radiobiology of human cells and tissues. In vitro radiosensitivity. The picture has changed in the 1980s. Int. J. Radiat. Biol. 56, 525-537 (1989).
25. J. F. Ward, DNA damage produced by ionizing radiation in mammalian cells: Identities, mechanisms of formation and reparability. Prog. Nucleic Acid Mol. Biol. 35, 95-125 (1988).
26. A. Haimovitz-Friedman, C. C. Kan, D. Ehleiter, R. S. Persaud, M. McLoughlin, Z. Fuks and R. N. Kolesnick, Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J. Exp. Med. 180, 525-535 (1994).
27. T. Miyashita, S. Krajewski, M. Krajewska, H. G. Wang, H. K. Line, D. A. Liebermann, B. Hoffman and J. C. Reed, Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9, 1799-1805 (1994).
28. J. C. Reed, Double identity for proteins of the bcl-2 family. Nature 387, 773-776 (1997).
29. + antiporter. J. Biol. Chem. 259, 5809-5815 (1984).
30. + antiporter glycoprotein of 110 kDa. Science 247, 723-726 (1990).
31. T. R. Hesketh, J. P. Moore, J. D. H. Morris, M. V. Taylor. J. Rogers, G. A. Smith and J. C. Metcalfe, A common sequence of calcium and pH signals in the mitogenic stimulation of eukaryotic cells. Nature 313, 481-484 (1983).
32. +-antiport. J. Biol. Chem. 270, 3203-3211 (1995).
33. J. M. Weinberg, J. A. Davis, N. F. Roeser and M. A. Venkatachalam, Role of intracellular pH during cytoprotection of proximal tubule cells by glycine or acidosis. J. Am. Soc. Nephrol. 5, 1314-1323 (1994).
34. G. F. Barbiero, F. Duranti, G. Bonelli, J. S. Amenta and F. M. Baccino, Intracellular ionic variations in the apoptotic death of L cells by inhibitors of cell cycle progression. Exp. Cell Res. 217, 410-418 (1995).
35. J. Lotem, E. J. Cragoe and L. Sachs, Rescue from programmed cell death in leukemic and normal myeloid cells. Blood 78, 953-960 (1991).
36. + antiporter in suppression of apoptosis by granulocyte macrophage colony-stimulating factor and interleukin-3. J. Biol. Chem. 267, 9980-9987 (1992).
37. J. Caceres-Cortes, D. Rajotte, J. Dumouchel, P. Haddad and T. Hoang, Product of the steel locus suppresses apoptosis in hemopoietic cells. Comparison with pathways activated by granulocyte macrophage colony-stimulating factor. J. Biol. Chem. 269, 12084-12091 (1994).
38. R. A. Gottlieb, Cell acidification in apoptosis. Apoptosis 1, 40-48 (1996).
39. A. H. Wyllie, M. J. Arends, R. G. Morris, S. W. Walker and G. Evan, The apoptosis endonuclease and its regulation. Semin. Immunol. 4, 389-397 (1992).
40. B. F. Trump and I. K. Berezesky, Calcium-mediated cell injury and cell death. FASEB J. 9, 219-228 (1995).
41. S. Durant, F. Homo and D. Duval, Calcium and A23187-induced cytolysis of mouse thymocytes. Biochem. Biophys. Res. Commun. 93, 385-391 (1980).
42. E. K. Asem, M. Li and B. K. Tsang, Calcium ionophores increase intracellular pH in chicken granulosa cells. J. Mol. Endocrinol. 9, 1-6 (1992).
43. M. D. Story, L. C. Stephens, S. P. Tomasovic and R. E. Meyn, A role for calcium in regulating apoptosis in rat thymocytes irradiated in vitro. Int. J. Radiat. Biol. 61, 243-251 (1992).
44. J. V. Bonventre and J. Y. Cheung, Effects of metabolic acidosis on viability of cells exposed to anoxia. Am. J. Physiol. 249, C149-C159 (1985).
45. W. G. Nayler, R. Ferrari, P. A. Poole-Wilson and C. E. Yepez, A protective effect of a mild acidosis on hypoxic heart muscle. J. Mol. Cell. Cardiol. 11, 1053-1071 (1979).