Synthesis of a radioiodinated park nucleotide analog: A new tool for antibacterial screen development

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 41, Issue 8, 1998, Pages 705-716

  Eid, Clark N ^a,b   Nesler, Michael J ^a,c   Zia Ebrahimi, Mohammad ^a   Wu, Chuyn Yeh Ernie ^a   Yao, Raymond ^a   Cox, Karen ^a   Richardson, John ^a  

^a ELI LILLY AND COMPANY   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Park nucleotide; Peptidoglycan; Radioiodinated; Screen

Indexed keywords

ANTIBODIES; ASSAYS; BIOCHEMISTRY; PARKS;

ANTIBACTERIALS; BACTERIAL CELLS; BUILDING BLOCKES; CELL WALLS; NUCLEOTIDE ANALOGUES; OH -; PARK NUCLEOTIDE; PEPTIDOGLYCANS; RADIOIODINATED; SCREEN;

NUCLEOTIDES;

IODINE 125; NUCLEOTIDE DERIVATIVE; PARK NUCLEOTIDE; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ARTICLE; BACTERIAL CELL WALL; DRUG SCREENING; DRUG SYNTHESIS; GLYCOPROTEIN SYNTHESIS; ISOTOPE LABELING;

BACTERIA (MICROORGANISMS);

EID: 0031819986     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(1998080)41:8<705::AID-JLCR119>3.0.CO;2-N     Document Type: Article

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14. Normal phase silica gel was deactivated by stirring in acetone followed by removing solvent under vacuum at room temperature.
15. 3Si to provide 1.