Activation of T cells from the intestinal lamina propria of the pig

Scandinavian Journal of Immunology

Volumn 48, Issue 2, 1998, Pages 177-182

  Bailey, M ^a   Plunkett, F ^a   Clarke, A ^a   Sturgess, D ^a   Haverson, K ^a   Stokes, C ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANTIGENICITY; ARTICLE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; EFFECTOR CELL; IMMUNOREGULATION; INTESTINE MUCOSA; LAMINA PROPRIA; MEMORY CELL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SWINE; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD45; CELLS, CULTURED; INTERLEUKIN-2; INTESTINAL MUCOSA; LYMPHOCYTE ACTIVATION; POLYMERASE CHAIN REACTION; RNA, MESSENGER; S PHASE; SPLEEN; SWINE; T-LYMPHOCYTES; TIME FACTORS;

EID: 0031817549     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1998.00365.x     Document Type: Article

References (27)

1. Russell GJ, Bhan AK, Winter HS. The distribution of T and B lymphocyte populations and MHC class II expression in human fetal and postnatal intestine. Ped Res 1990;27:239-44.
2. Vega-Lopez MA, Telemo E, Bailey M, Stevens K, Stokes CR. Immune cell distribution in the small intestine of the pig: immunohistological evidence for an organized compartmentalization in the lamina propria. Vet Immunol Immunopathol 1993;37:49-60.
3. + and show increased coexpression of CD45R0 in celiac disease. Eur J Immunol 1990;20:1825-30.
4. James SP, Zeitz M. Human gastrointestinal mucosal T cells. In: Ogra L, Mestecky J, Lamm ME, Strober W. McGhee JR, Bienenstock J, eds. Handbook of Mucosal Immunology. San Diego: Academic Press, 1994:275-85.
5. Qiao L, Schurmann G, Betzler M, Meuer SC. Activation and signaling status of human lamina propria T lymphocytes. Gastroenterology 1991;101:1529-36.
6. Targan SR, Deem RL, Liu M, Wang S, Nel A. Definition of a lamina propria T-cell responsive state - enhanced cytokine responsiveness of T-cells stimulated through the CD2 pathway. J Immunol 1995;154:664-75.
7. Boirivant M, Fuss I, Fiocchi C, Klein JS, Strong SA, Strober W. Hypoproliferative human lamina propria T-cells retain the capacity to secrete lymphokines when stimulated via CD2/CD28 pathways. Proc Assoc Am Phys 1996;108:55-67.
8. Meuer SC, Autschbach F, Schurmunn G, Golling M, Braunstein J, Qiao L. Molecular mechanisms securing unresponsiveness in lamina propria T-lymphocytes. Ann NY Acad Sci 1996;778:174-84.
9. Akbar AN, Terry L, Timms A, Beverley PCL, Janossy G. Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. J Immunol 1988;140:2171-8.
10. Bottomly K, Luqman M, Greenbaum L et al. A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines. Eur J Immunol 1989;19:617-23.
11. Luqman M, Johnson P, Trowbridge I, Bottomly K. Differential expression of the alternatively spliced exons of murine CD45 in Th1 and Th2 cell clones. Eur J Immunol 1991;21:17-22.
12. + T cells after alloantigen exposure. Immunol 1992;75:632-8.
13. James SP, Kwan WC, Sneller MC. T cells in inductive and effector compartments of the intestinal mucosal immune system of nonhuman primates differ in lymphokine mRNA expression, lymphokine utilization, and regulatory function. J Immunol 1990;144:1251-6.
14. Bailey M, Hall L, Bland PW, Stokes CR. Production of cytokines by lymphocytes from spleen, mesenteric lymph node and intestinal lamina propria of pigs. Immunol 1994;82:577-83.
15. Taylor PM, Thomas DB, Mills KHG. In vitro culture of T cell clones. In: Klaus G. ed. Lymphocytes: A Practical Approach. IRL Press, 1987:133-47.
16. Bailey M, Stevens K, Bland PW, Stokes CR. A monoclonal antibody recognising an epitope associated with pig interleukin-2 receptors. J Immunol Meth 1992;153:85-91.
17. Bailey M, Williams NA, Wilson AD, Stokes CR. Probit: weighted probit regression analysis for estimation of biological activity. J Immunol Meth 1992;153:261-2.
18. Lunney JK, Pescovitz MD. Phenotypic and functional chracterisation of pig lymphocyte populations. Vet Immunol Immunopathol 1987;17:135-44.
19. Zuckermann FA, Binns RM, Husmann R et al. Analyses of monoclonal antibodies reactive with porcine CD44 and CD45. Vet Immunol Immunopathol 1994;43:293-305.
20. Saalmuller A. Characterization of swine leukocyte differentiation antigens. Immunol Today 1996;17:352-4.
21. Salmon M, Pilling D, Borthwick NJ et al. The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis. Eur J Immunol 1994;24:892-9.
22. Wilson AD, Haverson K, Bland PW, Stokes CR, Bailey M. Expression of class II MHC antigens on normal pig intestinal endothelium. Immunol 1996;88:98-103.
23. Batten P, Yacoub MH, Rose ML. Effect of human cytokines (IFN-g, TNF-a, IL-1b, IL-4) on porcine endothelial cells: induction of MHC and adhesion molecules and functional significance of these changes. Immunol 1996;87:127-33.
24. Marelli-Berg FM, Hargreaves REG, Carmichael P, Dorling A, Lombardi G, Lechler RI. Major histocompatibility complex class II-expressing endothelial cells induce allospecific nonresponsiveness in naive T cells. J Exp Med 1996;183:1603-12.
25. Boirivant M, Pica R, Demaria R, Testi R, Pallone F, Strober W. Stimulated human lamina propria T-cells manifest enhanced FAS-mediated apoptosis. J Clin Invest 1996;98:2616-22.
26. Zhang XH, Giangreco L, Broome HE, Dargan CM, Swain SL. Control of CD4 effector fate - transforming growth-factor-beta-1 and interleukin-2 synergize to prevent apoptosis and promote effector expansion. J Exp Med 1995;182:699-709.
27. Akbar AN, Borthwick NJ, Wickremasinghe RG et al. Interleukin-2 receptor common gamma-chain signalling cytokines regulate activated T-cell apoptosis in response to growth factor withdrawal - selective induction of anti-apoptotic (bcl-2, bcl-x(1)) but not proapoptotic (bax, bcl-x(s)) gene-expression. Eur J Immunol 1996;26:294-9.