Evidence that glypican is a receptor mediating β-amyloid neurotoxicity in PC12 cells

European Journal of Neuroscience

Volumn 10, Issue 6, 1998, Pages 2085-2093

  Schulz, Joachim G ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Alzheimer' disease; Cell culture; Glycosaminoglycan; Heparan sulphate; Rat

Indexed keywords

AMYLOID BETA PROTEIN; GLYPICAN; HEPARAN SULFATE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL STRAIN; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

AMYLOID BETA-PROTEIN; ANIMALS; BINDING, COMPETITIVE; CARBOHYDRATE CONFORMATION; CARBOHYDRATE METABOLISM; CELL COUNT; CELL MEMBRANE; HEPARAN SULFATE PROTEOGLYCANS; HEPARITIN SULFATE; NEUROTOXINS; OSMOLAR CONCENTRATION; PC12 CELLS; POLYSACCHARIDES; RATS; RECEPTORS, CELL SURFACE; SULFATES; TIME FACTORS;

EID: 0031817009     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.1998.00220.x     Document Type: Article

References (4)

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3. Baeuerle, P.A. & Huttner, W.B. (1986) Chlorate - a potent inhibitor of protein sulfation in intact cells. Biochem. Biophys. Res. Commun., 141, 870-877.
4. Behl, C., Davis, J.B., Lesley, R. & Schubert, D. (1994) Hydrogen peroxide mediates amyloid beta protein toxicity. Cell, 77, 817-827.