β-N-acetylhexosaminidase in peripheral blood lymphocytes and monocytes in the different forms and stages of multiple sclerosis

Journal of Neurochemistry

Volumn 71, Issue 3, 1998, Pages 1168-1176

  Orlacchio, Antonio ^a   Martino, Sabata ^a   Sarchielli, Paola ^a   Gallai, Virgilio ^a   Emiliani, Carla ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Isoenzymes; Lymphocytes; Monocytes; Multiple sclerosis; Plasma membranes; N Acetylhexosaminidase

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE; GLUCOSAMINE DERIVATIVE; ISOENZYME;

ADULT; ARTICLE; CELL MEMBRANE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; LYMPHOCYTE; LYSOSOME; MONOCYTE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL;

EID: 0031816456     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71031168.x     Document Type: Article

References (32)

1. Altmann F., Schwihla H., Staudacher E., Glossl J., and Marz L. (1995) Insect cells contain an unusual, membrane-bound β-N-acetylglucosaminidase probably involved in the processing of protein N-glycans. J. Biol. Chem. 270, 17344-17349.
2. Antel J. P., Freedman M. S., Brodovsky S., Francis G. S., and Duquette P. (1989) Activated suppressor cell function in severely disabled patients with multiple sclerosis. Ann. Neurol. 25, 204-207.
3. Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of proteins utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
4. Brunette D. M. and Till J. E. (1971) A rapid method for the isolation of L-cell surface membranes using an aqueous two phase polymer system. J. Membr. Biol. 5, 215-224.
5. Chofflon M., Weiner H. L., Morimoto C., and Hafler D. A. (1988) Loss of functional suppression is linked to decreases in circulating suppressor inducer (CD4+2H4+) T cells in multiple sclerosis. Ann. Neurol. 24, 185-191.
6. Cuzner M. L. and Davison A. N. (1973) Changes in cerebral lysosomal enzyme activity and lipids in multiple sclerosis. J. Neurol. Sci. 19, 29-36.
7. Cuzner M. L., Davison A. N., and Rudje P. (1978) Proteolytic enzyme activity of blood leucocytes and cerebrospinal fluid in multiple sclerosis. Ann. Neurol. 4, 337-344.
8. Datti A., Emiliani C., Capocchi G., and Orlacchio A. (1991) β-N-Acetylhexosaminidases in human cerebrospinal fluid and serum of patients with multiple sclerosis. Clin. Chim. Acta 200, 73-80.
9. Dobrossy L., Pavelic Z. P., and Bernacky R. J. (1981) A correlation between cell surface sialyltransferase, sialic acid, and glycosidase activities and the implantability of B16 murine melanoma. Cancer Res. 41, 2262-2266.
10. Emiliani C., Beccari T., Tabilio A., Orlacchio A., Hosseini R., and Stirling J. L. (1990) An isoenzyme with properties similar to β-N-acetylhexosaminidase S is expressed in the promyelocytic cell line HL 60. Biochem. J. 267, 111-117.
11. Emiliani C., Martino S., Orlacchio A., Vezza R., Nenci G. G., and Gresele P. (1995a) Platelet glycohydrolase activities: characterization and release. Cell. Biochem. Funct. 13, 31-39.
12. Emiliani C., Capocchi G., Zampolini M., and Orlacchio A. (1995b) Association between seric β-N-acetylhexosaminidase isoenzyme patterns and multiple sclerosis. Clin. Chem. Enzyme Commun. 7, 1-7.
13. Emiliani C., Martino S., Stirling J. L., and Orlacchio A. (1995c) Influence of cell differentiation and protein kinase C activation on subcellular distribution of β-N-acetylhexosaminidases of HL60 cells. Physiol. Chem. Phys. Med. NMR 27, 369-378.
14. Goi G., Caputo D., Bairati C., Lombardo A., Burlina A. B., Ferrante P., Cazzullo C. L., and Tettamanti G. (1993) Enzyme of lysosomal origin in the cerebrospinal fluid and plasma of patients with multiple sclerosis. Eur. Neurol. 33, 1-4.
15. Gravel R. A., Clarke J. T. R., Kaback M. M., Mahuran D. J., Sandhoff K., and Suzuki K. (1995) The GM2 gangliosidoses, in The Metabolic Basis of Inherited Disease (Scriver C. V., Beaudet A. L., Sly W. S., and Valle D., eds), pp. 2839-2879. McGraw-Hill, New York.
16. Halonen T., Kiljelainem H., Pitkanen A., and Riekkinen P. (1987) Lysosomal hydrolases in cerebrospinal fluid of multiple sclerosis patients. J. Neurol. Sci. 79, 267-274.
17. Hintzen R. Q., Polman C. H., Lucas C. J., and van Lier R. A. W. (1992) Multiple sclerosis: immunological findings and possible implications for therapy. J. Neuroimmunol. 39, 1-10.
18. Hirsch H. E., Duquette P., and Parks M. E. (1976) The quantitative histochemistry of multiple sclerosis plaques. Acid proteinase and other acid hydrolases. J. Neurochem. 26, 505-512.
19. Hultberg B. and Holsson J. E. (1978) Aberrant diagnostic value of determinations of lysosomal hydrolases in CSF of patients with neurological diseases. Acta Neurol. Scand. 57, 201-215.
20. Hultberg B. and Holsson J. E. (1979) Lysosomal hydrolases in CSF patients with multiple sclerosis. Acta Neurol. Scand. 59, 23-30.
21. Kurtzke J. F. (1983) Rating neurologic impairment in multiple sclerosis: an Expanded Disability Status scale (EDSS). Neurology 33, 1444-1452.
22. Lambert C. C. (1989) Ascidian eggs release glycosidase activity which aids in the block against polyspermy. Development 105, 415-420.
23. Mahuran D. J., Novak A., and Lowden J. A. (1985) The lysosomal hexosaminidase isoenzymes. Curr. Top. Biol. Res. 12, 229-288.
24. Martino S., Emiliani C., Orlacchio A., Hosseini R., and Stirling J. L. (1995) β-N-Acetylhexosaminidases A and S have similar subcellular distribution in HL 60 cells. Biochim. Biophys. Acta 1243, 489-495.
25. Martino S., Emiliani C., Tabilio A., Falzetti F., Stirling J. L., and Orlacchio A. (1997) Distribution of active α and β subunits of β-N-acetylhexosaminidase as a function of leukaemic cell type. Biochim. Biophys. Acta 1335, 5-15.
26. Miller D. J., Gong X., and Shur D. B. (1993) Sperm require α-N-acetylhexosaminidase to penetrate through the egg zona pellucida. Development 118, 1279-1298.
27. Ormerod I. E. C., Miller D. H., McDonald W. I., du Boulay E. P., Rudje P., Kendall B. E., Mosely I. F., Johnson G., Tofts P. S., and Halliday A. M. (1987) The role of NMR imaging in the assessment of multiple sclerosis and isolated neurological lesions: a quantitative study. Brain 110, 1579-1616.
28. Poser C. M., Paty D. W., Sheinberg I., McDonald W. J., Floyd A. D., Ebers G. C., Johnson K. P., Sibley W. A., Silberberg D. H., and Tourtellotte W. W. (1983) New diagnostic criteria for multiple sclerosis. Guidelines for research protocols. Ann. Neurol. 13, 227-231.
29. Riekkinen P., Palo J., and Askikainen I. (1977) Lysosomal enzymes in the lymphocytes and granulocytes of patients with multiple sclerosis. Acta Neurol. Scand. 56, 83-86.
30. Steinman L. (1996) Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell 85, 299-302.
31. Warren L., Jardillier J. C., and Ordentlich P. (1991) Secretion of lysosomal enzymes by drug-sensitive and multiple drug-resistant cells. Cancer Res. 51, 1996-2001.
32. Yates C. M. and Wilson H. (1973) Lysosomal enzyme in motor neurone disease and multiple sclerosis. Clin. Chim. Acta 47, 397-402.