Allergens in combination have a synergistic effect on the elicitation response: A study of fragrance-sensitized individuals

British Journal of Dermatology

Volumn 139, Issue 2, 1998, Pages 264-270

  Johansen, J D ^a   Skov, L ^a   Volund, A ^b   Andersen, K ^c   Menne T ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NOVO NORDISK A S   (Denmark)

^c ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

PERFUME;

ALLERGENICITY; ARTICLE; CONCENTRATION RESPONSE; CONTACT ALLERGY; ECZEMA; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATCH TEST; PRIORITY JOURNAL; RISK ASSESSMENT;

ALLERGENS; DERMATITIS, ALLERGIC CONTACT; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; DRUG SYNERGISM; FEMALE; HUMANS; LASER-DOPPLER FLOWMETRY; MALE; PATCH TESTS; PERFUME; REGIONAL BLOOD FLOW; SKIN;

EID: 0031816328     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1998.02363.x     Document Type: Article

References (21)

1. Johansen JD, Rastogi SC, Menné T. Contact allergy to popular perfumes: assessed by patch test, use test and chemical analysis. Br J Dermatol 1996; 135: 419-22.
2. Johansen JD, Menné T. Fragrance contact allergy. Not such an infrequent disease. A review. Cosmetics Toiletries 1998; 113: 47-50.
3. Adams R, Maibach HI. A five-year study of cosmetic reactions. J Am Acad Dermatol 1985; 13: 1062-9.
4. Wilkinson DS, Fregert S, Magnusson B et al. Terminology of contact dermatitis. Acta Derm Venereol (Stockh) 1970; 50: 287-92.
5. Bircher A, Boer EM, Agner T et al. Guidelines for measurements of cutaneous blood flow by laser Doppler flowmetry. A report from the Standardization Group of The European Society of Contact Dermatitis. Contact Dermatitis 1994; 30: 65-72.
6. Volund A. Application of the four-parameter logistic model to bioassay: comparison with slope ratio and parallel line models. Biometrics 1978; 34: 357-66.
7. Andersen KE, Liden C, Hansen J, Volund A. Dose-response testing with nickel sulphate using the TRUE test in nickel-sensitive individuals. Multiple nickel sulphate patch test reaction do not cause an 'angry back'. Br J Dermatol 1993; 123: 50-6.
8. Agresti A. Analysis of Ordinal Categorical Data. New York: Wiley, 1984.
9. Fisher AA. Compound ('synergistic') allergy to contactants. Cutis 1986; 38: 101-2.
10. Johansen JD, Menné T. The fragrance mix and its constituents: a 14-year material. Contact Dermatitis 1995; 32: 18-23.
11. Menné T, White IR, Brunzeel DP, Dooms-Goossens A. Patch test reactivity to the PPD-black-rubber-mix (industrial rubber chemicals) and individual ingredients. Contact Dermatitis 1992; 26: 354.
12. Menné T, Hjorth N. Routine patch testing with paraben esters. Contact Dermatitis 1988; 19: 189-91.
13. Krasteva M, Garrigue JL, Horrand F et al. Suboptimal non-inflammatory concentration of haptens may elicit a contact sensitivity reaction when used as a mix. Contact Dermatitis 1996; 35: 279-82.
14. McLelland J, Shuster S. Contact dermatitis with negative patch tests: the additive effect of allergens in combination. Br J Dermatol 1990; 122: 623-30.
15. Nielsen NH, Menné T. Allergic contact sensitization in an unselected Danish population. Acta Derm Venereol (Stockh) 1992; 72: 456-60.
16. Edman B. Computerized analysis of concomitant contact allergens. Contact Dermatitis 1991; 24: 110-13.
17. Mitchell JC. Multiple concomitant positive patch test reactions. Contact Dermatitis 1977; 3: 315-20.
18. Memon AA, Friedmann P. 'Angry back syndrome': a non-reproducible phenomenon. Br J Dermatol 1996; 135: 924-30.
19. Serup J, Agner T. Colorimetric quantification of erythema - a comparison of two colorimeters (Lange Micro Color and Minolta Chroma Meter CR-200) with a clinical scoring scheme and laser-Doppler flowmetry. Clin Exp Dermatol 1990; 15: 267-72.
20. Eun HC, Marks R. Dose response relationships for topically applied antigens. Br J Dermatol 1990; 122: 491-9.
21. Berenbaum MC. What is synergy. Pharmacol Rev 1988; 41: 93-141.