Provirus load in patients with human T-cell leukemia virus type 1 uveitis correlates with precedent Graves' disease and disease activities

Japanese Journal of Cancer Research

Volumn 89, Issue 6, 1998, Pages 608-614

  Ono, Ayako ^a,b   Ikeda, Eiko ^b   Mochizuki, Manabu ^b   Matsuoka, Masao ^c   Yamaguchi, Kazunari ^c   Sawada, Takashi ^d   Yamane, Sumitaka ^d   Tokudome, Shinkan ^e   Watanabe, Toshiki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

^d EISAI CO LTD   (Japan)

^e NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

Author keywords

Disease activities; Graves' disease; HTLV 1 uveitis; Provirus load; sIL 2R

Indexed keywords

DNA; HUMAN T CELL LEUKEMIA VIRUS ANTIBODY; INTERLEUKIN 2 RECEPTOR;

ARTICLE; DISEASE ACTIVITY; FEMALE; GRAVES DISEASE; HUMAN; HUMAN T CELL LEUKEMIA VIRUS 1; IMMUNOASSAY; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROVIRUS; RECURRENT DISEASE; UVEITIS; VIRUS LOAD;

EID: 0031815403     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1998.tb03262.x     Document Type: Article

References (52)

1. Mochizuki, M., Watanabe, T., Yamaguchi, K., Takatsuki, K., Yoshimura, K., Shirao, M., Nakashima, S., Mori, S., Araki, S. and Miyata, N. HTLV-1 uveitis: a distinct clinical entity caused by HTLV-1. Jpn. J. Cancer Res., 83, 236-239 (1992).
2. Mochizuki, M., Watanabe, T., Yamaguchi, K., Tajima, K., Yoshimura, K., Nakashima, S., Shirao, M., Araki, S., Miyata, N. and Mori, S. An uveitis associated with human T-lymphotropic virus type-1 (HTLV-1): seroepidemiological, clinical and virological studies. J. Infect. Dis., 166, 943-944 (1992).
3. Mochizuki, M., Watanabe, T., Yamaguchi, K., Yoshimura, K., Nakashima, S., Shirao, M., Araki, S., Takatsuki, K., Mori, S. and Miyata, N. An uveitis associated with human T-lymphotropic type-1. Am. J. Ophthalmol., 114, 123-129 (1992).
4. Mochizuki, M., Tajima, K., Watanabe, T. and Yamaguchi, K. Human T lymphotropic virus type 1 uveitis. Br. J. Ophthalmol., 78, 149-154 (1994).
5. Yoshimura, K., Mochizuki, M., Araki, S., Miyata, N., Yamaguchi, K., Tajima, K. and Watanabe, T. Clinical and immunologic features of human T-cell lymphotropic virus type I uveitis. Am. J. Ophthalmol., 116, 156-163 (1993).
6. Ono, A., Mochizuki, M., Yamaguchi, K., Miyata, N. and Watanabe, T. Immunological and virological characterization of the primary infiltrating cells in the aqueous humor of HTLV-1 uveitis; accumulation of the HTLV-1-infected cells and constitutive expression of viral and IL-6 mRNAs. Invest. Ophthalmol. Visual Sci., 38, 676-689 (1997).
7. Yamaguchi, K., Mochizuki, M., Watanabe, T., Yoshimura, K., Shirao, M., Araki, S., Miyata, N., Mori, S., Kiyokawa, T. and Takatsuki, K. Human T lymphotropic virus type 1 uveitis after Graves' disease. Br. J. Ophthalmol., 78, 163-166 (1994).
8. Ozawa, Y., Migita, M., Watanabe, T., Okuda, I., Takeshita, A., Takagi, A. and Shishiba, Y. Development of Graves' ophthalmopathy and uveitis after radioiodine therapy for Graves' disease in a patient with HTLV-1 associated myelopathy (HAM). Intern. Med., 33, 564-568 (1994).
9. Mizokami, T., Okamura, K., Kohno, T., Sato, K., Ikenoue, H., Kuroda, T., Inokuchi, K. and Fujishima, M. Human T-lymphotropic virus type I-associated uveitis in patients with Graves' disease treated with methylmercaptoimidazole. J. Clin. Endocrinol. Metab., 80, 1904-1907 (1995).
10. Ono, A., Mochizuki, M., Yamaguchi, K., Miyata, N. and Watanabe, T. Increased number of circulating HTLV-1 infected cells in peripheral blood mononuclear cells of HTLV-1 uveitis patients: a quantitative polymerase chain reaction study. Br. J. Ophthalmol., 79, 270-276 (1995).
11. Gessain, A., Barin, F., Vernant, J. C., Gout, O., Maurs, L., Calender, A. and de The, G. Antibodies to human T lymphotropic virus type-1 in patients with tropical spastic paraparesis. Lancet, ii, 407-410 (1985).
12. Osame, M., Usuku, K., Izumo, S., Ijichi, N., Amitani, H. and Igata, A. HTLV-1-associated myelopathy, a new clinical entity. Lancet. i, 1031-1032 (1986).
13. Yoshida, M., Osame, M., Usuku, K., Matsumoto, M. and Igata, A. Viruses detected in HTLV-1 associated myelopathy and adult T-cell leukemia are identical in DNA blotting. Lancet, i, 1085-1086 (1987).
14. Yoshida, M., Osame, M., Kawai, H., Toita, M., Kuwasaki, N., Nishida, Y., Hiraki, Y., Takahashi, K., Nomura, K., Sonoda, S., Eiraku, N., Ijichi, S. and Usuku, K. Increased replication of HTLV-1 in HTLV-1-associated myelopathy. Ann. Neurol., 26, 331-335 (1989).
15. Greenberg, S. J., Jacobson, S., Waldma, T. A. and McFarlin, D. E. Molecular analysis of HTLV-1 proviral integration and T cell receptor arrangement indicates that T cells in tropical spastic paraparesis are polyclonal. J. Infect. Dis., 159, 741-744 (1989).
16. Gessain, A., Saal, F., Gout, O., Daniel, M. T., Flandrin, G., de The, G., Peries, J. and Sigaux, F. High human T-cell lymphotropic virus Type 1 proviral DNA load with polyclonal integration in peripheral blood mononuclear cells of French West Indian, Guianese and African patients with tropical spastic paraparesis. Blood, 75, 428-433 (1990).
17. Kira, J., Koyanagi, Y., Yamada, T., Itoyama, Y., Goto, I., Yamamoto, N., Sasaki, H. and Sakaki, Y. Increased HTLV-1 proviral DNA in HTLV-1-associated myelopathy: a quantitative polymerase chain reaction study. Ann. Neurol., 29, 194-201 (1991).
18. Furukawa, Y., Fujisawa, J., Osame, M., Toita, M., Sonoda, S., Kubota, R., Ijichi, S. and Yoshida, M. Frequent clonal proliferation of human T-cell leukemia virus type 1 (HTLV-1)-infected T cells in HTLV-1-associated myelopathy (HAM-TSP). Blood, 80, 1012-1015 (1992).
19. Osame, M., Matsumoto, M., Usuku, K., Izumo, S., Ijichi, N., Amitani, H., Tara, M. and Igata, A. Chronic progressive myelopathy associated with elevated antibodies to human T-lymphotropic virus type 1 and adult T-cell leukemia like cells. Ann. Neurol., 21, 117-122 (1987).
20. Matsumura, M., Kushida, S., Ami, Y., Suga, T., Uchida, K., Kameyama, T., Terano, A., Inoue, Y., Okochi, K., Sato, H. and Miwa, M. Quantitation of HTLV-1 provirus among seropositive blood donors: relation with antibody profile using synthetic peptides. Int. J. Cancer. 55, 220-222 (1993).
21. Ishihara, S., Okayama, A., Stuber, S., Horinouchi, H., Shioiri, K., Murai, K., Kubota, R., Yamashita, R., Tachibana, N., Tsubouchi, H. and Mueller, N. Association of HTLV-I antibody profile of asymptomatic carriers with proviral DNA levels of peripheral blood mononuclear cells. J. Acquir. Immune Defic. Syndr., 7, 199-203 (1994).
22. Morand-Joubert, L., Mariotti, M., Reed, D., Petit, J.-C. and Lefrere, J.-J. Correlation between viral DNA load and serum anti p19 antibody concentration in symptomless human T-lymphotropic virus type-I (HTLV-I)-infected individuals. Int. J. Cancer, 60, 156-159 (1995).
23. Miyata, H., Kamahora, T., Iha, S., Katamine, S., Miyamoto, T. and Hino, S. Dependency of antibody titer on provirus load in human T lymphotropic virus type I carriers: an interpretation for the minor population of seronegative carriers. J. Infect. Dis., 171, 1455-1460 (1995).
24. Yamaguchi, K., Nishimura, Y., Kiyokawa, T. and Takatsuki, K. Elevated serum levels of soluble interleukin-2 receptors in HTLV-1-associated myelopathy. J. Lab. Clin. Med., 114, 407-410 (1989).
25. Wattel, E., Vartanian, J. P., Pannentier, C. and Wain-Hobson, S. Clonal expansion of human T-cell leukemia virus type I-infected cells in asymptomatic and symptomatic carriers without malignancy. J. Virol., 69, 2863-2868 (1995).
26. Nussenblatt, R. B., Palestine, A. G., Chan, C. and Roberge, F. Standardization of vitreal inflammatory activity in intermediate and posterior uveitis. Ophthalmology, 92, 467-471 (1985).
27. Blackburn, G. F., Shah, H. P., Kenten, J. H., Leland, J., Kamin, R. A., Link, J., Peterman, J., Powell, M. J., Shah, A., Talley, D. B., Tyagi, S. K., Wilkins, E., Wu, T.-G. and Massey, R. J. Electrochemiluminescence detection for development of immunoassays and DNA probe assays for clinical diagnosis. Clin. Chem., 37/9, 1534-1539 (1991).
28. Namba, Y., Naraki, T., Watanabe, K., Yamane, S. and Mukojima, T. Studies on new immunoassay method using electrochemiluminescence (ECL). Jpn. J. Clin. Lab. Assoc., 21, 680-686 (1996) (in Japanese).
29. Wilson, R., McKillop, J. H., Chopra, M. and Thompson, J. A. The effect of antithyroid drugs on B and T cell activity in vitro. Clin. Endocrinol., 28, 389-397 (1988).
30. Karlsson, F. A. and Totterman, T. H. Immunomodulation by methimazole therapy in Graves' disease: rapid changes in activation stage of circulating regulatory T cell subsets. B cells and NK cells. Clin. Exp. Immunol., 74, 258-263 (1988).
31. Daenke, S., Nightingale, S., Cruickshank, J. K. and Bangham, C. R. Sequence variants of human T-cell lymphotropic virus type I from patients with tropical spastic paraparesis and adult T-cell leukemia do not distinguish neurological from leukemic isolates. J. Virol., 64, 1278-1282 (1990).
32. Nishimura, M., McFarlin, D. E. and Jacobson, S. Sequence comparisons of HTLV-1 from HAM/TSP patients and their asymptomatic spouses. Neurology, 43, 2621-2624 (1993).
33. Major, M. E., Nightingale, S. and Desselberger, U. Complete sequence conservation of the human T cell leukemia virus type I tax gene within a family cluster showing different pathologies. J. Gen. Virol., 74, 2531-2537 (1993).
34. Ono, A., Miura, T., Araki, S., Yamaguchi, K., Takatsuki, K., Mori, S., Hayami, M., Mochizuki, M. and Watanabe, T. Subtype analysis of HTLV-1 in patients with HTLV-1 uveitis. Jpn. J. Cancer Res., 85, 767-770 (1994).
35. Terada, K., Katamine, S., Eguchi, K., Moriuchi, M., Kita, H., Shimada, I., Yamashita, K., Iwata, Y., Tsuji, S., Nagataki, S. and Miyamoto, T. Prevalence of serum and salivary antibodies to HTLV-1 in Sjögren's syndrome. Lancet, 344, 1116-1169 (1994).
36. Bagnasco, M., Venuti, D., Ciprandi, G., Pesce, G., Paolieri, F. and Canonica, G. W. The effect of methimazole on the immune system is unlikely to operate directly on T lymphocytes. J. Endocrinol. Invest., 13, 493-499 (1990).
37. Escobar-Morreale, H. F., Serrano-Gotarredona, J., Villar, L. M., Garcia-Robles, R., Gonzalez-Porque, P., Sancho, J. M. and Varela, C. Methimazole has no dose-related effect on the serum concentrations of soluble class I major histocompatibility complex antigens, soluble interleukin-2 receptor, and beta 2-microglobulin in patients with Graves' disease. Thyroid, 6, 29-36 (1996).
38. Dhawan, S., Weeks, B., Abbasi, F., Gralnick, H. R., Notkins, A. L., Klotman, M. E., Yamada, K. M. and Klotman, P. E. Increased expression of α4β1 and α5β1 integrins on HTLV-1 infected lymphocytes. Virology, 197, 778-781 (1993).
39. Imai, T., Tanaka, Y., Fukudome, K., Takagi, S., Araki, K. and Yoshie, O. Enhanced expression of LFA-3 on human T-cell lines and leukemic cells carrying human T-cell leukemia virus type I. Int. J. Cancer. 55, 811-816 (1993).
40. Fukudome, K., Furuse, M., Fukuhara, N., Orita, S., Imai, T., Takagi, S., Nagira, M., Hinuma, Y. and Yoshie, O. Strong induction of ICAM-1 in human T cells transformed by human T cell leukemia virus type I and depression of ICAM-1 or LFA-1 in adult T cell leukemia derived cell lines, Int. J. Cancer, 52, 418-427 (1992).
41. Tatewaki, M., Yamaguchi, K., Matsuoka, M., Ishii, T., Miyasaka, M., Mori, S., Takatsuki, K. and Watanabe, T. Constitutive overexpression of the L-selectin gene in fresh leukemic cells of adult T-cell leukemia that can be transactivated by human T-cell lymphotropic virus type I Tax. Blood, 86, 3109-3117 (1995).
42. Sagawa, K., Mochizuki, M., Masuoka, K., Katagiri, K., Katayama, T., Maeda, T., Tanimoto, A., Sugita, S., Watanabe, T. and Itoh, K. Immunopathological mechanisms of human T-cell lymphotropic virus type I (HTLV-1) uveitis: detection of HTLV-1-infected T cells in the eye and their constitutive cytokine production. J. Clin. Invest., 95, 852-858 (1995).
43. Mori, N. and Prager, D. Trunsactivation of the interleukin-1 alpha promoter by human T-cell leukemia virus type I and type II Tax proteins. Blood, 87, 3410-3417 (1996).
44. Albrecht, H., Shakhov, A. N. and Jongeneel, C. V. Transactivation of the tumor necrosis factor alpha promoter by the human T-cell leukemia virus type 1 Tax 1 protein. J. Virol., 66, 6191-6193 (1992).
45. Furukawa, Y., Osame, M., Kubota, R., Tara, M. and Yoshida, M. Human T-cell leukemia virus type-1 (HTLV-1) Tax is expressed at the same level in infected cells of HTLV-I-associated myelopathy or tropical spastic paraparesis patients as in asymptomatic carriers but at a lower level in adult T-cell leukemia cells. Blood, 85, 1865-1870 (1995).
46. Inoue, Y., Kuroda, N., Shiraki, H., Sato, H. and Maeda, Y. Neutralizing activity of human antibodies against the structural protein of human T-cell lymphotropic virus type I. Int. J. Cancer, 52, 877-880 (1992).
47. Iwahara, Y., Sawada, T., Taguchi, H., Hoshino, H., Umemoto, M., Take, H., Foung, S. and Miyoshi, I. Neutralizing antibody to vesicular stomatitis virus (HTLV-I) pseudotype in infants born to seropositive mothers. Jpn. J. Cancer Res., 84, 114-116 (1993).
48. Desgrange, C., Souche, S., Vernant, J. C., Smadja, D., Vahle, A. and Horal, P. Identification of novel neutralization-inducing regions of the human T cell lymphotropic virus type I envelope glycoproteins with human HTLV-I-seropositive sera. AIDS Res. Hum. Retroviruses. 10, 163-173 (1994).
49. Kamihira, S., Atogami, S., Sohda, H., Momita, S., Yamada, Y. and Tomonaga, M. Significance of soluble interleukin-2 receptor levels for evaluation of the progression of adult T-cell leukemia. Cancer. 74, 2753-2758 (1994).
50. Inoue, J., Seiki, M., Taniguchi, T., Tsuru, S. and Yoshida, M. Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1. EMBO J., 5, 2883-2887 (1986).
51. Matsumoto, M., Sugimoto, M., Nakashima, H., Imamura, F., Kawano, O., Uyama, E., Takatsu, K. and Araki, S. Spontaneous T cell proliferation and release of soluble interleukin-2 receptors in patients with HTLV-1-associated myelopathy. Am. J. Trop. Med. Hyg., 42, 365-373 (1990).
52. Koukkou, E., Panayiotidis, P., Alevizou-Terzaki, V. and Thalassinos, N. High levels of serum soluble interleukin 2 receptors in hyperthyroid patients: correlation with serum thyroid hormones and independence from the etiology of the hyperthyroidism. J. Clin. Endocrinol. Met., 73, 771-776 (1991).