Effect of venlafaxine on the pharmacokinetics of alprazolam

Psychopharmacology Bulletin

Volumn 34, Issue 2, 1998, Pages 211-219

  Amchin, Jess ^a  

^a WYETH AYERST RESEARCH   (United States)

Author keywords

Alprazolam; Drug interaction; Pharmacokinetics; Venlafaxine

Indexed keywords

ALPRAZOLAM; VENLAFAXINE;

ADULT; ARTICLE; DEPRESSION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG INHIBITION; DRUG METABOLISM; FEMALE; HUMAN; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

ADOLESCENT; ADULT; ALPRAZOLAM; ANTI-ANXIETY AGENTS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BIOTRANSFORMATION; CYCLOHEXANOLS; DRUG INTERACTIONS; FEMALE; HUMANS; MALE;

EID: 0031814912     PISSN: 00485764     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

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2. Andersson, T; Miners, JO; Veronese, ME; and Birkett, DJ. Diazepam metabolism by human liver microsomes is mediated by both Smephenytoin hydroxylase and CYP3A isoforms. Br. J. Clin. Pharmacol. 28:131-137, 1994.
3. Ball, SE; Ahern, D; Scatina, J; and Kao, J. Venlafaxine: In vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9, and CYP1A2. Br. J. Clin. Pharmacol. 43:619-626, 1997.
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