Analysis of methods for reducing false positives in the automated detection of clustered microcalcifications in mammograms

Medical Physics

Volumn 25, Issue 8, 1998, Pages 1502-1506

  Nagel, Rufus H ^a   Nishikawa, Robert M ^a   Papaioannou, John ^a   Doi, Kunio ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Artificial neural networks; Breast cancer; Computer aided diagnosis; Digital mammography; Microcalcifications

Indexed keywords

COMPUTER AIDED DIAGNOSIS; DISEASES; MAMMOGRAPHY; NEURAL NETWORKS; X RAY SCREENS;

AUTOMATED DETECTION; AVERAGE NUMBERS; BREAST CANCER; CLINICAL EVALUATION; CLUSTERED MICROCALCIFICATIONS; DIGITAL MAMMOGRAPHY; FEATURE ANALYSIS; MICROCALCIFICATIONS;

CALCIFICATION (BIOCHEMISTRY);

ARTICLE; ARTIFICIAL NEURAL NETWORK; AUTOMATION; BREAST CALCIFICATION; COMPUTER ANALYSIS; DATA BASE; HUMAN; IMAGE ANALYSIS; MAMMOGRAPHY; PRIORITY JOURNAL;

EID: 0031814618     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.598326     Document Type: Article

References (21)

1. P Wingo, T. Tong, and S. Bolden, "Cancer statistics," Cancer J. Clin. 45, 8-30 (1995).
2. J. R. Harris, M. E. Lippman, U. Veronesi, and W. Willett, "Breast cancer," New. Eng. J. Med. 327, 390-398 (1992).
3. C. J. Baines, A. B. Miller, C. Wall, D. V. McFarlane, I. S. Simor, R. Jong, B. J Shapiro, L Audet, M. Petitclerc, D. Ouimet-Oliva, J. Ladouceur, G. Hebert, T. Minuk, G. Hardy, and H. Standing, "Sensitivity and specificity of first screen mammography in the Canadian national breast screening study: A preliminary report from five centers," Radiology 160, 295-298 (1986).
4. S. R. Pollei, F. A. Mettler, S. A. Bartow, and M. Moskowitz, "Occult breast cancer: Prevalence and radiographic detectability," Radiology 163, 459-462 (1987).
5. R. E. Bird, T. W. Wallace, and B. C. Yankaskas, "Analysis of cancers missed at screening mammography," Radiology 184, 613-617 (1992).
6. E. Thurfjell, K. Lernevall, and A. Taube, "Benefit of independent double reading in a population-based mammography screening program," Radiology 191, 241-244 (1994).
7. R M Nishikawa, Y. Jiang, M. L. Giger, K. Doi, R A. Schmidt, C J. Vyborny, W. Zhang, T. Ema, J. Papaioannou, D. E. Wolverton, U. Bick, R. Nagel, and Y Mao, "Performance of Automated CAD schemes for the detection and classification of clustered microcalcifications," in Digital Mammography, edited by A. G. Gale, S. M. Astley, D R. Dance, and A. Y. Cairns (Elsevier Science, Amsterdam, 1994), pp. 13-20.
8. H.-P. Chan, K. Doi, S. Galhotra, C. J. Vyborny, H. MacMahon, and P M. Jokich, "Image feature analysis and computer-aided diagnosis in digital radiography. I. Automated detection of microcalcifications in mammography," Med. Phys. 14, 538-548 (1987)
9. D. H. Davies and D. R. Dance, "The automatic computer detection of subtle calcifications in radiographically dense breasts," Phys. Med. Biol. 37, 1385-1390 (1992).
10. W. Zhang, K. Doi, M. L. Giger, R M. Nishikawa, and Y. Wu, "Computerized detection of clustered microcalcifications in digital mammograms using a shift-invariant artificial neural network," Med. Phys. 21, 517-524 (1994).
11. Y. Wu, K. Doi, M. L. Giger, and R. M. Nishikawa, "Computerized detection of clustered microcalcifications in digital mammograms: Applications of artificial neural networks," Med. Phys. 19, 555-560 (1992).
12. K. S. Woods, J. L. Solka, C. E. Priebe, C. C. Doss, K. W. Bowyer, and L. P. Clarke, "Comparative evaluation of pattern recognition techniques for detection of microcalcifications," Proc. SPIE 1905, 841-852 (1993).
13. H.-P. Chan, D. Wei, K. L. Lam, S.-C. B. Lo, B. Sahiner, M. Helvie, and D. D. Adler, "Computerized detection and classification of microcalcifications on mammograms," Proc. SPIE 2434, 612-620 (1995).
14. R. M Nishikawa, Y. Jiang, M. L. Giger, C. J. Vyborny, R. A. Schmidt, and U. Bick, "Characterization of the mammographic appearance of microcalcifications: applications in computer-aided diagnosis," Proc. SPIE 1898, 422-429 (1993).
15. T. Ema, K. Doi, R. M. Nishikawa, Y. Jiang, and J Papaioannou, "Image feature analysis and computer-aided diagnosis in mammography: Reduction of false-positive clustered microcalcifications using local edge-gradient analysis," Med. Phys. 22, 161-169 (1995).
16. H.-P. Chan, K. Doi, C. J. Vyborny, R. A. Schmidt, C. E. Metz, K. L. Lam, T. Ogura, Y. Wu, and H. MacMahon, "Improvement in radiologists' detection of clustered microcalcifications on mammograms: The potential of computer-aided diagnosis," Invest. Radiol. 25, 1102-1110 (1990).
17. H.-P. Chan, K. Doi, C. J. Vyborny, K L. Lam, and R. A. Schmidt, "Computer-aided detection of microcalcifications in mammograms: Methodology and preliminary clinical study," Invest. Radiol. 23, 664-671 (1988).
18. R. M. Nishikawa, M. L. Giger, K. Doi, C. J. Vyborny, and R. A. Schmidt, "Computer-aided detection of clustered microcalcifications using digital mammograms," Med. Biol. Eng. Comput. 33, 174-178 (1995).
19. D. B. Kopans, Breast Imaging (J. B Lippincott, Philadelphia, 1989).
20. R. M Nishikawa, M. L. Giger, K. Doi, C. J. Vyborny, and R. A. Schmidt, "Computer-aided detection of clustered microcalcifications: An improved method for grouping detected signals," Med. Phys. 20, 1660-1666 (1993).
21. R M. Nishikawa, R. C. Haldemann, J. Papaioannou, M. L. Giger, P. Lu, R. A. Schmidt, D. E. Wolverton, U Bick, and K. Doi, "Initial experience with a prototype clinical "intelligent" mammography workstation for computer-aided diagnosis," Proc. SPIE 2434, 65-71 (1995)