Comparison of psychomotor functions and sedation following premedication with oral diazepam and clonidine in children

International Journal of Clinical Pharmacology and Therapeutics

Volumn 36, Issue 6, 1998, Pages 336-339

  Jatti, K ^a   Batra, Y K ^a   Bhardwaj, N ^a   Malhotra, S ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Clonidine; Diazepam; Pediatrics; Premedication; Psychomotor assessment; Sedation

Indexed keywords

CLONIDINE; DIAZEPAM;

ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ELECTIVE SURGERY; GENERAL ANESTHESIA; HUMAN; ORAL DRUG ADMINISTRATION; PERFORMANCE; PREMEDICATION; PRESCHOOL CHILD; PSYCHOMOTOR ACTIVITY; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; SEDATION;

ADMINISTRATION, ORAL; ANTI-ANXIETY AGENTS; CHILD; CHILD, PRESCHOOL; CLONIDINE; CONSCIOUS SEDATION; DIAZEPAM; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INTELLIGENCE; INTELLIGENCE TESTS; MALE; PREMEDICATION; PROSPECTIVE STUDIES; PSYCHOMETRICS; PSYCHOMOTOR PERFORMANCE; SYMPATHOLYTICS;

EID: 0031814401     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Aghajanian GK 1982 Central neuradrenrgic neurons: A locus for functional interplay between alpha-2 adrenoceptors and opiate receptors. J Clin Psych 43: 20-24
2. Anderson S, Mcguire R, Mckeown D 1985 Comparison of the cognitive effects of premedication with hyoscine and atropine. Br J Anaesth 57: 169-173
3. Barker RA, Nisbet HIA 1973 The objective measurement of sedation in children. A modified scoring system. Can Anaesth Soc J 20: 599-606
4. Bellaiche S, Bonnet F, Sperandio M, Lerougue D, Cannet G, Roujas FA 1991 Clonidine does not delay recovery from anaesthesia 66: 353-357
5. Hunt RD, Capper L, O'Connell P 1990 Clonidine in child and adolescent psychiatry. J Child Adolesc Psychopharmacol 1: 87-102
6. Jones RDM, Visram AR, Kornberg JP, Irwin MG, Gunawardene WMS 1994. Premedication with oral midazolam in children - An assessment of psychomotor function, anxiolysis, sedation, and pharmacokinetics. Anaesth Intens Care 22: 539-544
7. Korttila K, Linnoila M 1975 Psychomotor skills related to driving after intramuscular administration of diazepam and meperidine. Anaesthesiology 42: 685-691
8. Korttilla K, Manila MJ, Linnoila M 1976 Prolonged recovery after diazepam sedation: The influence of food, charcoal ingestion, and injection rate on the effects of intravenous diazepam. Br J Anaesth 48: 333-340
9. Linnoila M 1973 Drug effects on psychomotor skills related to driving, interaction of atropine, glycopyrronium, and alcohol. Eur J Clin Pharmacol 6: 107-111
10. Mikawa K, Maekawa N, Nishina K, Takao Y, Yaku H, Obara H 1993 Efficacy of oral clonidine premedication in children. Anaesthesiology 79: 926-931
11. Parnis SJ, Foate JA, Van der Walt JH, Short T, Crowe CE 1992 Oral midazolam is an effective premedication for children having day stay anaesthesia. Anaesth Intens Care 20: 9-14
12. Richards MJ, Skues MA, Jarvis AP, Prys-Roberts C 1990 Total i.v. anaesthesia with propofol and alfentanil: Dose requirements for propofol and the effect of premedication with clonidine. Br J Anaesth 65: 157-163
13. Sanders LD 1991 Recovery of psychological function after anaesthesia. Int Anaesthesiol Clin 29: 105-115
14. Seppala T, Korttila K, Hakkinen S, Linnoila M 1976 Residual effects and skills related to driving after single oral administration of diazepam, medazepam or lorazepam. Br J Clin Pharmacol 3: 831-841
15. Skelly AM, Bosioe MJ, Dawling S, Adanis AP 1984 A comparison of diazepam and midazolam as sedatives for minor oral surgery. Eur J Anaesthesiol 1:253-258
16. Slover RH, Klingensmith GJ, Gotlin RW, Radcliffe J 1984 A comparison of clonidine and standard provocative agents of growth hormone. Am J Dis Child 138: 314-317
17. Svensson TH, Bunney BS, Aghajanian GK 1986 Inhibition of both noradrenergic and serotonergic neurons in brain by alpha-2 agonist clonidine. Brain Res 92: 291-306
18. Vener TR 1993 A comparison of midazolam, diazepam, and placebo as oral anesthetic premedicants in younger children. J Clin Anesth 5: 58-61