Characterization of the immunopathogenic responses to ovalbumin peptide 323-339 in experimental immune-mediated blepharoconjunctivitis in Lewis rats

Current Eye Research

Volumn 17, Issue 8, 1998, Pages 763-769

  Fukushima, A ^a   Nishino, K ^a   Yoshida, O ^a   Ueno, H ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

Author keywords

Cellular immunity; Experimental immune mediated blepharo conjunctivitis; Lewis rat; Ovalbumin; Peptide

Indexed keywords

ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; FREUND ADJUVANT; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 2 RECEPTOR; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MEMBRANE ANTIGEN; OVALBUMIN;

ADOPTIVE TRANSFER; ALLERGIC CONJUNCTIVITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR IMMUNITY; CONJUNCTIVITIS; CONTROLLED STUDY; CROSS REACTION; EYELID; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOPATHOGENESIS; LYMPH NODE; MALE; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; RAT;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS; BLEPHARITIS; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; CONJUNCTIVITIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNITY, CELLULAR; IMMUNIZATION; IMMUNOGLOBULIN G; LYMPH NODES; LYMPHOCYTE ACTIVATION; MALE; OVALBUMIN; PEPTIDE FRAGMENTS; RATS; RATS, INBRED LEW;

EID: 0031814375     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.17.8.763.5152     Document Type: Article

References (24)

1. Donshik PC. Allergic conjunctivitis. Int Ophthalmol Clin. 1988;28:294-302.
2. Doherty MJ, Easty DL. Inflammatory and immunological cell profiles in a rat model of conjunctival immediate hypersensitivity. Clin Exp Allergy. 1989;19:449-455.
3. Colby K, Dohlman C. Vernal keratoconjunctivitis. Int Ophthalmol Clin. 1996;36:15-20.
4. Metz DP, Bacon AS, Holgate S, Lightman SL. Phenotypic characterization of T cells infiltrating the conjunctiva in chronic allergic eye disease. J Allergy Clin Immunol. 1996;98:686-696.
5. Abu el-Asrar AM, Van den Oord JJ, Geboes K, Missotten L, Emarah MH, Desmet V. Immunopathological study of vernal keratoconjunctivitis. Graefe's Arch Clin Exp Ophthalmol. 1989;227:374-379.
6. Fukushima A, Yoshida H, Iwamoto H, Yoshida O, Ueno H. The role of cellular immunity both in the induction and effector phases of experimental allergic blepharoconjunctivitis (EAC) in rats. Exp Eye Res. 1997;65:631-637.
7. Nitzan Y, Boldur I, Afgin Y, Barishak YR, Malik Z, Sompolinsky D. The dynamics of inflammation of the anterior eye in a novel experimental model for hypersensitivity. Cytobios. 1996;88:105-117.
8. Guillet JG, Lai MZ, Briner TJ, Smith JA, Gefter ML. Interaction of peptide antigens and class II major histocompatibility complex antigens. Nature. 1986;324:260-262.
9. Buus S, Sette A, Colon AM, Miles C, Grey HM. The relation between major histocompatibility complex (MHC) restriction and the capacity of la to bind immunogenic peptides. Science. 1987;235:1353-1358.
10. Falk K, Rotzschke O, Stevanovic S, Jung G, Rammensee HG. Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature. 1991;351:290-296.
11. Ota K, Matsui M, Milford EL, Mackin GA, Weiner HL, Hafler DA. T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature. 1990;346:183-187.
12. Martin R, McFarland HF, McFarlin DE. Immunological aspects of demyelinating disease. Annu Rev Immunol. 1992;10:153-187.
13. Greer JM, Sobel RA, Sette A, Southwood S, Lees MB, Kuchroo VK. Immunogenic and encephalitogenic epitope clusters of myelin proteolipid protein. J Immunol. 1996;156:371-379.
14. Joosten I, Wauben MH, Holewijn MC, et al. Direct binding of autoimmune disease related T cell epitopes to purified Lewis rat MHC class II molecules. Int Immunol. 1994;6:751-759.
15. Buus S, Colon S, Smith C, Freed JH, Miles C, Grey HM. Interaction between a "processed" ovalbumin peptide and la molecules. Proc Natl Acad Sci USA. 1986;83:3968-3971.
16. Renz H, Smith HR, Henon JE, Ray BS, Irvin CG, Gelfand EW. Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse. J Allergy Clin Immunol. 1992;89:1127-1138.
17. Renz H, Bradley K, Larsen GL, McCall C, Gelfand EW. Comparison of the allergenicity of ovalbumin and ovalbumin peptide 323-339. J Immunol. 1993;151:7206-7213.
18. Hu LH, Redmond TM, Sanui H, et al. Rat T-cell lines specific to a nonimmunodominant determinant of a retinal protein (IRBP) produce uveoretinitis and pinealitis. Cell Immunol. 1989;122:251-261.
19. Lanzavecchia A, Reid PA, Watts C. Irreversible association of peptides with class II MHC molecules in living cells. Nature. 1992;357:249-252.
20. Kilgus J, Jardetzky T, Gorga JC, Trzeciak A, Gillessen D, Sinigaglia F. Analysis of the permissive association of a malaria T cell epitope with DR molecules. J Immunol. 1991;146:307-315.
21. Langeland T. A clinical and immunological study of allergy to hen's egg white III: Allergens in hen's egg white studied by crossed radio-immunoelectrophoresis (CRIE). Allergy. 1982;37:521-530.
22. Calonge M, Pasor JC, Herreras JM, Gonzalez JL. Pharmacological modulation of vascular permeability in ocular allergy in the rat. Invest Ophthalmol Vis Sci. 1990;31:176-180.
23. Mochizuki M, Kuwabara T, McAllister C, Nussenblatt RB, Gery I. Adoptive transfer of experimental autoimmune uveoretinitis in rats: immunopathogenic mechanisms and histologic features. Invest Ophthalmol Vis Sci. 1985;26:1-9.
24. Kotake S, Wiggert B, Zhang XY, Redmond TM, Chader GJ, Gery I. Stimulation in vitro of lymphocytes for induction of uveoretinitis without any significant proliferation. J Immunol. 1990;145:534-539.