Apoptotic changes after pressure-induced ischemia-reperfusion injury in the rat retina

Journal of Japanese Ophthalmological Society

Volumn 102, Issue 7, 1998, Pages 417-424

  Nishiyama, Yoko ^a   Hayashi, Naoki ^a   Murayama, Koichiro ^a   Mori, Keisuke ^a   Yoneya, Shin ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; Ischemia reperfusion injury; Retina; TUNEL method

Indexed keywords

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; ELECTRON MICROSCOPY; NONHUMAN; PRESSURE; RAT; REPERFUSION INJURY; RETINA GANGLION CELL; RETINA ISCHEMIA;

ANIMALS; APOPTOSIS; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; MICROSCOPY, ELECTRON; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RETINA; RETINAL DISEASES;

EID: 0031814228     PISSN: 00290203     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Hughes WF : Quantitation of ischemic damage in the rat retina. Exp Eye Res 53 :573-582, 1991.
2. Anderson DR, Davis EB : Sensitivities of ocular tissues to acute pressure-induced ischemia. Arch Ophthalmol 93 : 267-274, 1975.
3. Szabo ME, Droy-Lefaix MT, Doly M, Carre C, Braquet P : Ischemia and reperfusion induced histologic changes in the rat retina. Invest Ophthalmol Vis Sci 32 . 1471-1478, 1991.
4. Gavrieli Y, Sherman Y, Ben-Sasson SA : Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation J Cell Biol 119:493-501, 1992.
5. Buchi ER : Cell death in rat retina after pressure - induced ischaemia-reperfusion insult : An electron microscopic study. I. Ganglion cell layer and inner nuclear layer. Exp Eye Res 55 : 605-613, 1992.
6. Buchi ER : Cell death in rat retina after pressure - induced ischaemia-reperfusion insult : Electron microscopic study. II. Outer nuclear layer. Jpn J Ophthalmol 36 : 62-68. 1992.
7. Migheli A, Attanasio A, Schiffer D : Ultrastructural detection of DNA strand breaks in apoptotic neural cells by in situ end-labelling technniques. J Pathol 176 : 27-35, 1995.
8. Ansari B, Coates PJ, Greenstein BD, Hall PA : In situ end-labelling detects DNA strand breaks in apoptosis and other physiological and pathological states. J Pathol 170 : 1-8, 1993.
9. Nakazawa H, Arroyo CM, Ichimori K, Saigusa Y, Minezaki K, Pronai L : The demonstration of DMPO spin adduct upon reperfusion using a low non-toxic concentration. J Free Rad Res Commun 14 : 297-302, 1991.
10. Olney JW : Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system. Exp Brain Res 14 : 61-76, 1971.
11. Louzada-Junior P, Dias JJ, Santos WF, Lachat JJ, Bradford HF, Coutinho-Netto J : Glutamate release in experimental ischaemia of the retina : An approach using microdialysis. J Neurochem 59 : 358-363, 1992.
12. Kuzuya T, Hoshida S, Kim Y, Nishida M, Fuji H, Kitabatake A, et al : Detection of oxygen-derived free radical generation in the canine postischemic heart during late phase of reperfusion. Cir Res 1 : 1160-1165, 1990.
13. Yoon YH, Marmor MF : Dextromethorphan protects retina against ischemic injury in vivo. Arch Ophthalmol 107 : 409-411, 1989.
14. Takahashi K, Lam TT, Edward DP, Buchi ER, Tso MO : Protective effects of flunarizine on ischemic injury in the rat retina. Arch Ophthalmol 110 : 862-870, 1992.
15. Zhang C, Takahashi K, Lam TT, Tso MO : Effects of fibroblast growth factor in retinal ischemia. Invest Ophthalmol Vis Sci 35 : 3163-3168, 1994.
16. Lam TT, Fu J, Hrynewycz M, Tso MO : The effect of aurintricarboxylic acid, and endonuclease inhibitor, on ischemia reperfusion damage in rat retina. J Ocul Pharmacol Ther 11 . 253-259, 1995.
17. Weber M, Mohand-Said S, Hicks D, Dreyfus H, Sahel JA : Monosialoganglioside GM 1 reduces ischemia reperfusion-induced injury in the rat retina. Invest Ophthalmol Vis Sci 37 : 267-273, 1996.