A low concentration of ethanol reduces the chemiluminescence of human granulocytes and monocytes but not the tumor necrosis factor alpha production by monocytes after endotoxin stimulation

Infection and Immunity

Volumn 66, Issue 6, 1998, Pages 2809-2813

  Parlesak, Alexandr ^a   Diedrich, Jens P ^a   Schäfer, Christian ^b   Bode, Christiane ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

^b ROBERT BOSCH HOSPITAL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ENDOTOXIN; REACTIVE OXYGEN METABOLITE;

ALCOHOLISM; ARTICLE; ENDOTOXEMIA; GRANULOCYTE FUNCTION; HOST RESISTANCE; HUMAN; HUMAN CELL; INFECTION SENSITIVITY; LEUKOCYTE ACTIVATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0031811947     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.6.2809-2813.1998     Document Type: Article

References (38)

1. Adams, H. G., and C. Jordan. 1984. Infections in the alcoholic. Med. Clin. North Am. 68:179-200.
2. Aniansson, H., O. Stendahl, and C. Dahlgren. 1984. Comparison between luminol- and lucigenin-dependent chemiluminescence of polymorphonuclear leukocytes. Acta Pathol. Microbiol. Immunol. Scand. Sect. C 92:357-361.
3. Atkinson, J. P., T. J. Sullivan, J. P. Kelly, and C. W. Parker. 1977. Stimulation by alcohols of cyclic AMP metabolism in human leukocytes. Possible role of cyclic AMP in the anti-inflammatory effects of ethanol. J. Clin. Invest. 60:284-294.
4. Babior, B. M. 1978. Oxygen-dependent microbial killing by phagocytes (second of two parts). N. Engl. J. Med. 298:721-725.
5. Barth, J., and K. G. Ravens. 1984. The effect of ethanol on luminol-dependent chemiluminescence of leukocytes. Blutalkohol 21:464-470.
6. Berton, G., and S. Gordon. 1985. Role of the plasma membrane in the regulation of Superoxide anion release by macrophages, p. 435-444. In R. Van Furth (ed.), Mononuclear phagocytes: characteristics, physiology, and function. Martinus Nijhoff, The Hague, The Netherlands.
7. Bishop, C. J., C. M. Rzepczyk, D. Stenzel, and K. Anderson. 1987. The role of reactive oxygen metabolites in lymphocyte-mediated cytolysis. J. Cell Sci. 87:473-481.
8. Bode, C., V. Kugler, and J. C. Bode. 1987. Endotoxemia in patients with alcoholic and non-alcoholic cirrhosis and in subjects with no evidence of chronic liver disease following acute alcohol excess. J. Hepatol. 4:8-14.
9. Bourne, H. R., L. M. Lichtenstein, K. L. Melmon, C. S. Henney, Y. Weinstein, and G. M. Shearer. 1974. Modulation of inflammation and immunity by cyclic AMP. Science 184:19-28.
10. Dentener, M. A., V. Bazil, E. J. Von Asmuth, M. Ceska, and W. A. Buurman. 1993. Involvement of CD14 in lipopolysaccharide-induced tumor necrosis factor-alpha, IL-6 and IL-8 release by human monocytes and alveolar macrophages. J. Immunol. 150:2885-2891.
11. Ewetz, L., J. Palmblad, and A. Thore. 1981. The relationship between luminol chemiluminescence and killing of Staphylococcus aureus by neutrophil granulocytes. Blut 43:373-381.
12. Follin, P., and C. Dahlgren. 1992. Phagocytosis by lipopolysaccharide-primed human neutrophils is associated with increased extracellular release of reactive oxygen metabolites. Inflammation 16:83-91.
13. Fukui, H., B. Brauner, J. C. Bode, and C. Bode. 1991. Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: reevaluation with an improved chromogenic assay. J. Hepatol. 12:162-169.
14. Gallin, J. I., J. A. Sandler, R. I. Clyman, V. C. Manganiello, and M. Vaughan. 1978. Agents that increase cyclic AMP inhibit accumulation of cGMP and depress human monocyte locomotion. J. Immunol. 120:492-496.
15. Harvath, L. 1979. Enhancement of granulocyte chemiluminescence with hydroxyl radical scavengers. Infect. Immun. 25:473-476.
16. Horan, T. D., D. English, and T. A. McPherson. 1982. Association of neutrophil chemiluminescence with microbicidal activity. Clin. Immunol. Immunopathol. 22:259-269.
17. Hynie, S., F. Lanefelt, and B. B. Fredholm. 1980. Effects of ethanol on human lymphocyte levels of cyclic AMP. In vitro: potentiation of the response to isoproterenol, prostaglandin E2 or adenosine stimulation. Acta Pharmacol. Toxicol. (Copenhagen) 47:58-65.
18. Kapp, A., M. Freudenberg, and C. Galanos. 1987. Induction of human granulocyte chemiluminescence by bacterial lipopolysaccharides. Infect. Immun. 55:758-761.
19. Kharazmi, A., A. Fomsgaard, R. S. Conrad, C. Galanos, and N. Hoiby. 1991. Relationship between chemical composition and biological function of Pseudomonas aeruginosa lipopolysaccharide: effect on human neutrophil chemotaxis and oxidative burst. J. Leukoc. Biol. 49:15-20.
20. Lehmeyer, J. E. and R. B. Johnston, Jr. 1978. Effect of anti-inflammatory drugs and agents that elevate intracellular cyclic AMP on the release of toxic oxygen metabolites by phagocytes: studies in a model of tissue-bound IgG. Clin. Immunol. Immunopathol. 9:482-490.
21. Libon, C., F. Forestier, J. Cotte-Laffitte, C. Labarre, and A. M. Quero. 1993. Effect of acute oral administration of alcohol on Superoxide anion production from mouse alveolar macrophages. J. Leukocyte Biol. 53:93-98.
22. Lieber, C. S. 1997. Ethanol metabolism, cirrhosis and alcoholism. Clin. Chim. Acta 257:59-84.
23. Nakagawara, M., K. Takeshige, H. Sumimoto, J. Yoshitake, and S. Minakami. 1984. Superoxide release and intracellular free calcium of calcium-depleted human neutrophils stimulated by N-formyl-methionyl-leucyl-phenylalanine. Biochim. Biophys. Acta 805:97-103.
24. Nilsson, E., T. Andersson, M. Fallman, K. Rosendahl, and J. Palmblad. 1992. Effects of ethanol on the chemotactic peptide-induced second messenger generation and Superoxide production in polymorphonuclear leukocytes. J. Infect. Dis. 166:854-860.
25. Nilsson, E. and J. Palmblad. 1988. Effects of ethanol on mechanisms for secretory and aggregatory responses of human granulocytes. Biochem. Pharmacol. 37:3237-3243.
26. Nilsson, E., P. Thomsen, L. Ericson, and J. Palmblad. 1995. Rabbit polymorphonuclear granulocyte function during ethanol administration - migration and oxidative responses in a joint with immune complex synovitis. Clin. Exp. Immunol. 102:137-143.
27. Patel, M., A. Keshavarzian, V. Kottapalli, B. Badie, D. Winship, and J. Z. Fields. 1996. Human neutrophil functions are inhibited in vitro by clinically relevant ethanol concentrations. Alcohol Clin. Exp. Res. 20:275-283.
28. Schopf, R. E., M. Trompeter, K. Bork, and B. Morsches. 1985. Effects of ethanol and acetaldehyde on phagocytic functions. Arch. Dermatol. Res. 277:131-137.
29. Schuett, C., T. Schilling, U. Gruenwald, W. Schoenfeld, and C. Krueger. 1992. Endotoxin-neutralizing capacity of soluble CD14. Res. Immunol. 143: 71-78.
30. Simchowitz, L., L. C. Fischbein, I. Spilberg, and J. P. Atkinson. 1980. Induction of a transient elevation in intracellular levels of adenosine-3′,5′-cyclic monophosphate by chemotactic factors: an early event in human neutrophil activation. J. Immunol. 124:1482-1491.
31. Smith, F. E., and D. L. Palmer. 1976. Alcoholism, infection and altered host defenses: a review of clinical and experimental observations. J. Chronic Dis. 29:35-49.
32. Szabo, G., P. Mandrekar, L. Girouard, and D. Catalano. 1996. Regulation of human monocyte functions by acute ethanol treatment: decreased tumor necrosis factor-alpha, interleukin-1 beta and elevated interleukin-10, and transforming growth factor-beta production. Alcohol Clin. Exp. Res. 20:900-907.
33. Takahashi, R., K. Edashige, E. F. Sato, M. Inoue, T. Matsuno, and K. Utsumi. 1991. Luminol chemiluminescence and active oxygen generation by activated neutrophils. Arch. Biochem. Biophys. 285:325-330.
34. Tobias, P. S., K. Soldau, J. A. Gegner, D. Mintz, and R. J. Ulevitch. 1995. Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14. J. Biol. Chem. 270:10482-10488.
35. Tokmakov, A. A., V. J. Denisenko, V. E. Stefanov, and V. Y. Vasiliev. 1992. Ethanol inhibition of the chemiluminescent response of stimulated macrophages. Biotechnol. Appl. Biochem. 15:115-119.
36. Van Dyke, K. 1987. Introduction to cellular chemiluminescence, neutrophils, macrophages, and monocytes, p. 3-22. In K. Van Dyke and V. Castranova (ed.), Cellular chemiluminescence. CRC Press, Boca Raton, Fia.
37. Verma, B. K., M. Fogarasi, and G. Szabo. 1993. Down-regulation of tumor necrosis factor alpha activity by acute ethanol treatment in human peripheral blood monocytes. J. Clin. Immunol. 13:8-22.
38. Wilson, M. E., D. P. Jones, P. Munkenbeck, and D. C. Morrison. 1982. Serum-dependent and -independent effects of bacterial lipopolysaccharides on human neutrophil oxidative capacity in vitro. J. Reticuloendothel. Soc. 31:43-57.