A potential molecular approach to ex vivo hematopoietic expansion with recombinant epidermal growth factor receptor-expressing adenovirus vector

Blood

Volumn 91, Issue 12, 1998, Pages 4509-4515

  Takahashi, Tokiharu ^b   Yamada, Kaoru ^b   Tanaka, Tomoyuki ^b   Kumano, Keiki ^b   Kurokawa, Mineo ^b   Takahashi, Tsuyoshi ^b   Hirano, Naoto ^b   Honda, Hiroaki ^b   Chiba, Shigeru ^b   Tsuji, Kohichiro ^b   Yazaki, Yoshio ^b   Nakahata, Tatsutoshi ^b   Hirai, Hisamaru ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CELL SURFACE RECEPTOR; CYCLOPHOSPHAMIDE; CYTOKINE; EPIDERMAL GROWTH FACTOR RECEPTOR; INTEGRIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT PROTEIN;

ADENOVIRUS; ARTICLE; CONTROLLED STUDY; EXPRESSION VECTOR; FLOW CYTOMETRY; GENE TARGETING; GENETIC TRANSDUCTION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; INTERNALIZATION; MONONUCLEAR CELL; PRIORITY JOURNAL;

EID: 0031811694     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.12.4509     Document Type: Article

References (36)

1. Emerson SG: Ex vivo expansion of hematopoietic precursors, progenitors, and stem cells: The next generation of cellular therapeutics. Blood 87:3082, 1996
2. Moore MAS: Expansion of myeloid stem cells in culture. Semin Hematol 32:183, 1995
3. + cells into the myeloid lineage. Blood 80:1405, 1992
4. Schwartz RM, Palsson BO, Emerson SG: Rapid medium perfusion rate significantly increases the productivity and longevity of human bone marrow cultures. Proc Natl Acad Sci USA 88:6760, 1991
5. Silver SM, Adams PT, Hutchinson RJ, Douville JW, Paul LA, Clarke MF, Palsson BO, Emerson SG: Phase I evaluation of ex vivo expanded hematopoietic cells produced by perfusion cultures in autologous bone marrow transplantation (BMT). Blood 82:297a, 1993 (abstr, suppl 1)
6. + cells in PIXY321: Phase I/II clinical studies. J Hematother 4:237, 1995
7. Brugger W, Heimfeld S, Berenson RJ, Mertelsmann R, Kanz L: Reconstitution of hematopoiesis after high-dose chemotherapy by autologous progenitor cells generated ex vivo. N Engl J Med 333:283, 1995
8. von Ruden T, Wagner EF: Expression of functional human EGF receptor on murine bone marrow cells. EMBO J 7:2749, 1988
9. Rosenfeld MA, Yoshimura K, Trapnell BC, Yoneyama K, Rosenthal ER, Dalemans W, Fukayama M, Bargon J, Stier LE, Stratford-Perricaudet L: In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium. Cell 68:143, 1992
10. Crystal RG, McElvaney NG, Rosenfeld MA, Chu CS, Mastrangeli A, Hay JG, Brody SL, Jaffe HA, Eissa NT, Danel C: Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nat Genet 8:42, 1994
11. Karlsson S, Humphries RK, Gluzman Y, Nienhuis AW: Transfer of genes into hematopoietic cells using recombinant DNA viruses. Proc Natl Acad Sc USA 82:158, 1985
12. Mitani K, Graham FL, Caskey CT: Transduction of human bone marrow by adenoviral vector. Hum Gene Ther 5:941, 1994
13. Haddada H, Ragot T, Cordier L, Duffour MT, Perricaudet M: Adenoviral interleukin-2 gene transfer into P815 tumor cells abrogates tumorigenicity and induces antitumoral immunity in mice. Hum Gene Ther 4:703, 1993
14. Miyake S, Makimura M, Kanegae Y, Harada S, Sato Y, Takamori K, Tokuda C, Saito I: Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc Natl Acad Sc USA 93:1320, 1996
15. Kanegae Y, Lee G, Sato Y, Tanaka M, Nakai M, Sakaki T, Sugano S, Saito I: Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase. Nucleic Acids Res 23:3816, 1995
16. Kanegae Y, Makimura M, Saito I: A simple and efficient method for purification of infectious recombinant adenovirus. Jpn J Med Sci Biol 47:157, 1994
17. Nakahata T, Ogawa M: Hemopoietic colony-forming cells in umbilical cord blood with extensive capability to generate mono- and multipotential hemopoietic progenitors. J Clin Invest 70:1324, 1982
18. Nakahata T, Spicer SS, Ogawa M: Clonal origin of human erythro-eosinophilic colonies in culture. Blood 59:857, 1982
19. Imai T, Koike K, Kubo T, Kikuchi T, Amano Y, Takagi M, Okumura N, Nakahata T: Interleukin-6 supports human megakaryocytic proliferation and differentiation in vitro. Blood 78:1969, 1991
20. Sutherland HJ, Eaves CJ, Eaves AC, Dragowska W, Lansdorp PM: Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro. Blood 74:1563, 1989
21. Sutherland HJ,Lansdorp PM, Henkelman DH, Eaves AC, Eaves CJ: Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers. Proc Natl Acad Sc USA 87:3584, 1990
22. Eaves CJ, Cashman JD, Eaves AC: Methodology of long-term culture of human hemopoietic cells. J Tissue Culture Methods 13:55, 1991
23. Wickham TJ, Mathias P, Cheresh DA, Nemerow GR: Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell 73:309, 1993
24. Wattel E, Vanrumbeke M, Abina MA, Cambier N, Preudhomme C, Haddada H, Fenaux P: Differential efficacy of adenoviral mediated gene transfer into cells from hematological cell lines and fresh hematological malignancies. Leukemia 10:171, 1996
25. Davies K (ed): Adventures with adenovirus [editorial]. Nat Genet 3:1, 1993
26. Watanabe T, Kuszynski C, Ino K, Heimann DG, Shephard HM, Yasui Y, Maneval DC, Talmadge JE: Gene transfer into human bone marrow hematopoietic cells mediated by adenovirus vectors. Blood 87:5032, 1996
27. Neering SJ, Hardy SF, Minamoto D, Spratt SK, Jordan CT: Transduction of primitive human hematopoietic cells with recombinant adenovirus vectors. Blood 88:1147, 1996
28. v integrin expression on cultured human macrophages. Proc Natl Acad Sci USA 90:2517, 1993
29. 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery. J Virol 69:2257, 1995
30. Niwa H, Yamamura K, Miyazaki J: Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108:193, 1991
31. Pain B, Woods CM, Saez J, Flickinger T, Raines M, Peyrol S, Moscovici C, Moscovici MG, Kung HJ, Jurdic P: EGF-R as a hemopoietic growth factor receptor: The c-erbB product is present in chicken erythrocytic progenitors and controls their self-renewal. Cell 65:37, 1991
32. Hayman MJ, Meyer S, Martin F, Steinlein P, Beug H: Self-renewal and differentiation of normal avian erythroid progenitor cells: Regulatory roles of the TGF alpha/c-ErbB and SCF/c-kit receptors. Cell 74:157, 1993
33. Chen LL, Gansbacher B, Gilboa E, Taetle R, Oval J, Hibbs MS, Huang CK, Clawson ML, Bilgrami S, Schlessinger J: Retroviral gene transfer of epidermal growth factor receptor into HL60 cells results in a partial block of retinoic acid-induced granulocytic differentiation. Cell Growth Differ 4:769, 1993
34. Sibilia M, Wagner EF: Strain-dependent epithelial defects in mice lacking the EGF receptor. Science 269:234, 1995
35. Berardi AC, Wang A, Levine JD, Lopez P, Scadden DT: Functional isolation and characterization of human hematopoietic stem cells. Science 267:104, 1995
36. Sui X, Tsuji K, Tanaka R, Tajima S, Muraoka K, Ebihara Y, Ikebuchi K, Yasukawa K, Taga T, Kishimoto T, Nakahata T: gp130 and c-Kit signalings synergize for ex vivo expansion of human primitive hemopoietic progenitor cells. Proc Natl Acad Sci USA 92:2859, 1995