Adenosine receptor blockade enhances myocardial stunning without a sustained effect on fluorine-18-FDG uptake postreperfusion

Journal of Nuclear Medicine

Volumn 39, Issue 6, 1998, Pages 944-949

  McFalls, Edward O ^a,b   Baldwin, Douglas ^a   Marx, David ^a   Jaimes, Diane ^a   Fashingbauer, Peggy ^a   Ward, Herbert B ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b VA MEDICAL CENTER   (United States)

Author keywords

Adenosine; Fluorine 18 fluorodexoyglucose; Glucose; Metabolism; PET; Reperfusion injury; Stunning

Indexed keywords

8 PHENYLTHEOPHYLLINE; ADENOSINE; ADENOSINE RECEPTOR; FLUORODEOXYGLUCOSE F 18; GLUCOSE;

ANIMAL MODEL; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG UPTAKE; FEMALE; GLUCOSE TRANSPORT; HEART MUSCLE BLOOD FLOW; HEART MUSCLE ISCHEMIA; HEART MUSCLE OXYGEN CONSUMPTION; HEMODYNAMICS; MALE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECEPTOR BLOCKING; REPERFUSION INJURY; STUNNED HEART MUSCLE; SWINE;

ANIMALS; CORONARY CIRCULATION; FLUORODEOXYGLUCOSE F18; GLUCOSE; HEMODYNAMIC PROCESSES; LACTIC ACID; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION; MYOCARDIAL STUNNING; MYOCARDIUM; OXYGEN CONSUMPTION; RECEPTORS, PURINERGIC P1; SWINE; THEOPHYLLINE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0031810640     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Downey J, Liu G, Thornton J. Adenosine and the anti-infarct effects of preconditioning. Cardiovasc Res 1993;27:3-8.
2. Olafsson B, Forman M, Puett D, et al. Reduction of reperfusion injury in the canine preparation by intracoronary adenosine: importance of the endothelium and the no-reflow phenomenon. Circulation 1987;76:1135-1145.
3. Pitarys C II, Virmani R, Vildibill H Jr, Jackson E, Forman M. Reduction of myocardial reperfusion injury by intravenous adenosine administered during the early reperfusion period. Circulation 1991;83:237-247.
4. Dorheim T, Hoffman A, Van Wylen D, Mentzer R. Enhanced interstitial fluid adenosine attenuates myocardial stunning. Surgery 1991;110:136-145.
5. Kirkeboen K, Ilebekk A, Tonnessen T, et al. Cardiac contractile function after repetitive brief ischemia: effects of nucleoside transport inhibition. Am J Physiol 1994;267:H57-H65.
6. Kitakaze M, Hori M, Sato H, et al. Beneficial effects of alpha 1-adrenoceptor activity on myocardial stunning in dogs. Circ Res 1991;68:1322-1339.
7. Zughaib M, Abd-Elfattah A, Jeroudi M, et al. Augmentation of endogenous adenosine attenuates myocardial stunning independently of coronary flow or hemodynamic effects. Circulation 1993;88:2359-2369.
8. Wannenburg T, De Tombe P, Little W. Effect of adenosine on contractile state and oxygen consumption in isolated rat hearts. Am J Physiol 1994;267:H1429-H1436.
9. 1-adenosine receptors. Am J Physiol 1989;257:H1952-H1957.
10. Jeremy R, Koretsune Y, Marban E, Becker L. Relation between glycolysis and calcium homeostasis in postischemic myocardium. Circ Res 1992;70:1180-1190.
11. Mainwaring R, Lasley R, Rubio R, Wyatt D, Mentzer R Jr. Adenosine stimulates glucose uptake in the isolated rat heart. Surgery 1988;103:445-449.
12. Law W, McLane M. Adenosine enhances myocardial glucose uptake only in the presence of insulin. Metabolism 1991;40:947-952.
13. Finegan B, Lopaschuk G, Coulson C, Clanachan A. Adenosine alters glucose use during ischemia and reperfusion in isolated rat hearts. Circulation 1993;87:900-908.
14. National Institutes of Health. Guide for the care and use of laboratory animals, NIH publication no. 85-23, revised ed. Bethesda, MD: U.S. National Institutes of Health; 1985.
15. Duncker D, Klassen C, Ishibashi Y, Herrlinger S, Pavek T, Bache R. Effect of temperature on myocardial infarction in swine. Am J Physiol 1996;270:H1189-H1199.
16. Bache R, Dai X, Schwartz J, Homans D. Role of adenosine in coronary vasodilation during exercise. Circ Res 1988;62:846-853.
17. McFalls E, Duncker D, Ward H, Fashingbauer P. Impaired endothelium-dependent vasodilation of coronary resistance vessels in severely stunned porcine myocardium. Basic Res Cardiol 1995;90:498-506.
18. Rynning S, Brunvand H, Birkeland S, Hexeberg E, Grong K. Endogenous adenosine attenuates myocardial stunning by antiadrenergic effects exerted during ischemia and not during reperfusion. J Cardiovasc Pharmacol 1995;25:432-439.
19. Ratib O, Phelps M, Huang S. Positron tomography with deoxyglucose for estimating local myocardial glucose metabolism. J Nucl Med 1982;23:577-586.
20. McFalls E, Ward H, Fashingbauer P, Gimmestad G, Palmer B. Myocardial blood flow and FDG retention in acutely stunned porcine myocardium. J Nucl Med 1995;36:637-643.
21. McFalls E, Baldwin D, Palmer B, Marx D, Jaimes D, Ward H. Regional glucose uptake within hypoperfused swine myocardium as measured by positron emission tomography. Am J Physiol 1997;272:H343-H349.
22. Kirkeboen K, Aksnes G, Lande K, Ilebekk A. Role of adenosine for reactive hyperemia in normal and stunned porcine myocardium. Am J Physiol 1992;263:H1119-H1127.
23. Headrick J, Ely S, Matherne G, Berne R. Myocardial adenosine, flow, and metabolism during adenosine antagonism and adrenergic stimulation. Am J Physiol 1993;264:H61-H70.
24. Zhu Q, Chen S, Zou C. Protective effects of an adenosine deaminase inhibitor on ischemia-reperfusion injury in isolated perfused rat heart. Am J Physiol 1990;259: H835-H838.
25. Bolling S, Bies L, Bove E, Gallagher K. Augmenting intracellular adenosine improves myocardial recovery. J Thorac Cardiovasc Surg 1990;99:469-474.
26. Bolli R. Mechanism of myocardial "stunning". Circulation 1990;82:723-738.
27. Janier M, Vanoverschelde J-L, Bergmann S. Adenosine protects ischemic and reperfused myocardium by receptor-mediated mechanisms. Am J Physiol 1993;264: H163-H170.
28. Yao Z, Gross G. Glibenclamide antagonizes adenosine A1 receptor-mediated cardio-protection in stunned canine myocardium. Circulation 1993;88:235-244.
29. Miura T, Goto M, Urabe K, Endoh A, Shimamoto K, Iimura O. Does myocardial stunning contribute to infarct size limitation by ischemic preconditioning? Circulation 1991;84:2504-2512.
30. Matsuda M, Catena T, Van der Heide R, Jennings R, Reimer K. Cardiac protection by ischaemic preconditioning is not mediated by myocardial stunning. Cardiovasc Res 1993;27:585-592.
31. Owen P, Dennis S, Opie L. Glucose flux regulates onset of ischemic contracture in globally underperfused rat hearts. Circ Res 1990;66:344-354.
32. 1 receptor mechanism. Am J Physiol 1992;263:H1460-H1465.
33. Angello D, Headrick J, Coddington N, Berne R. Adenosine antagonism decreases metabolic but not functional revocery from ischemia. Am J Physiol 1991;260:H193-H200.
34. 6-(L-2-Phenylisopropyl)adenosine. Circ Res 1991;69:791-799.
35. McFalls E, Ward H, Fashingbauer P, Palmer B. Effects of dobutamine stimulation on regional myocardial glucose uptake poststunning as measured by positron emission tomography. Cardiovasc Res 1994;28:1030-1035.
36. Schneider C, Nguyen V, Taegtmeyer H. Feeding and fasting determine postischemic glucose utilization in isolated working rat hearts. Am J Physiol 1991;260:H542-H548.
37. Buxton D, Schelbert H. Measurement of regional glucose metabolic rates in reperfused myocardium. Am J Physiol 1991;261:H2058-H2068.