Antiamnesic action of cromakalim, a potassium channel opener, in mice treated with hypoxia- and cerebral ischemia-type stress stimuli

Cellular and Molecular Neurobiology

Volumn 18, Issue 4, 1998, Pages 429-436

  Nakao, Kaoru ^a   Tokuyama, Shogo ^a   Takahashi, Masakatsu ^a   Kaneto, Hiroshi ^a   Ueda, Hiroshi ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

Amnesia; Cerebral ischemia; Hypoxia; Learning and memory; Mice; Stress

Indexed keywords

CROMAKALIM; POTASSIUM CHANNEL STIMULATING AGENT;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN HYPOXIA; BRAIN ISCHEMIA; BRAIN PROTECTION; CHROMATIN CONDENSATION; CONTROLLED STUDY; DENTATE GYRUS; DRUG MECHANISM; GRANULE CELL; HIPPOCAMPUS; HISTOCHEMISTRY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; LEARNING; MALE; MEMORY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA;

EID: 0031810495     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022553616572     Document Type: Article

References (20)

1. Ankarcrona, M., Dypbukt, J. M., Bonfoco, E., Zhivotovsky, B., Orrenius, S., Lipton, S. A., and Nicotera, P. (1995). Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15:961-973.
2. Carpenter, G. A., and Grossberg, S. (1993). Normal and amnesic learning, recognition and memory by neural model of cortico-hippocampal interactions. Trends Neurosci. 16:131-137.
3. Edward, G., and Weston, A. H. (1993). The pharmacology of ATP-sensitive potassium channel. Annu. Rev. Pharmacol. Toxicol. 33:597-693.
4. + channel openers and "natural" cardioprotection. Trends Pharmacol. Sci. 13:269-272.
5. Finta, E. P., Harms, L., Sevcik, J., Fischer, H.-D., and Illes, P. (1993). Effects of potassium channel openers and their antagonists on rat locus coeruleus neurons. Br. J. Pharmacol. 109:308-315.
6. Grover, G. J., McCullough, J. R., D'Alonzo, A. J., Sargent, C. A., and Atwal, K. S. (1995). Cardioprotective profile of the cardiac-selective ATP-sensitive potassium channel opener BMS-180448. J. Cardiovasc. Pharmacol. 25:40-50.
7. Hahn, J. S., Aizenman, E., and Lipton, S. A. (1988). Central Mammalian neurons resistant to glutamate toxicity and made sensitive by elevated extracellular calcium: Toxicity blocked by the N-methyl-D-aspartate antagonist MK-801. Proc. Natl. Acad. Sci. USA 85:6556-6560.
8. Haley, T. J., and McCormick, W. G. (1957). Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse. Br. J. Pharmacol. 12:12-15.
9. Hamilton, T. C., Weir, S. W., and Weston, A. H. (1986). Comparison of the effects of BRL 34915 and verapamil on electrical and mechanical activity in rat portal vein. Br. J. Pharmacol. 88:103-111.
10. + channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, amyloid β-protein precursor genes and neuronal death in rat hippocampus. Proc. Natl. Acad. Sci. USA 90:9431-9435.
11. + channels in cerebral ischemic preconditioning. Proc. Natl. Acad. Sci. USA 92:4666-4670.
12. Jodar, L., Takahashi, M., and Kaneto, H. (1996). FS stress induced long-lasting memory facilitation: Involvement of cholinergic pathways. Pharmacol. Biochem. Behav. 53:735-740.
13. Kojima, M., and Kaneto, H. (1989). Preparation of cerebral ischemia-induced amnesic model in mice and ameliorative effect of several compounds on the model. Folia Pharmacol. Japon. 94:223-228.
14. Mourre, C., Ben-Ari, Y., Bernardi, H., Fosset, M., and Lazdunski, M. (1989). Antidiabetic sulfonylureas: Localization of binding sites in the brain and effects on the hyperpolarization induced by anoxia in hippocampal slices. Brain Res. 486:159-164.
15. + channels both post-synaptically and on mossy fibers. Brain Res. 540:340-344.
16. Phillis, J. W., and O'Regan, M. H. (1996). Mechanisms of glutamate and aspartate release in the ischemic rat cerebral cortex. Brain Res. 730:150-164.
17. + channels. Trends Pharmacol. Sci. 10:431-435.
18. Szatkowski, M., and Attwell, D. (1994). Triggering and execution of neuronal death in brain ischaemia: Two phases of glutamate release by different mechanisms. Trends Neurosci. 17:359-365.
19. Yung, R. S. K. During, M. J., Aquila, W. J., Tendler, D., and Ley, E. (1992). Hypoxia increases extracellular concentrations of excitatory and inhibitory neurotransmitters in subsequently induced seizure: In vivo microdialysis study in the rabbit. Exp. Neurol. 117:204-209.
20. Zini, S., Roisin, M. P., Armengaud, C., and Ben-Ari, Y. (1993). Effect of potassium channel modulators on the release of glutamate induced by ischaemic-like conditions in rat hippocampal slices. Neurosci. Lett. 153:202-205.