메뉴 건너뛰기




Volumn 41, Issue 7, 1998, Pages 839-843

A lipoic acid-gamma linolenic acid conjugate is effective against multiple indices of experimental diabetic neuropathy

Author keywords

Alpha lipoic acid; Gamma linolenic acid; Nerve conduction; Nerve growth factor; Neuropeptide Y; Rat; Substance P

Indexed keywords

CRESOL; GAMMA LINOLENIC ACID; NERVE GROWTH FACTOR; NEUROPEPTIDE Y; SUBSTANCE P; THIOCTIC ACID;

EID: 0031810195     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250050996     Document Type: Article
Times cited : (89)

References (41)
  • 1
    • 0342437466 scopus 로고    scopus 로고
    • Diabetic neuropathy: Pathogenesis and current treatment perspectives
    • Biessels GJ, Van Dam PS (1997) Diabetic neuropathy: pathogenesis and current treatment perspectives. Neurosci Res Commun 20: 1-10
    • (1997) Neurosci Res Commun , vol.20 , pp. 1-10
    • Biessels, G.J.1    Van Dam, P.S.2
  • 2
    • 0029128239 scopus 로고    scopus 로고
    • Pathology and pathogenetic mechanisms of diabetic neuropathy
    • Yagihashi S (1996) Pathology and pathogenetic mechanisms of diabetic neuropathy. Diabetes Metab Rev 11: 193-225
    • (1996) Diabetes Metab Rev , vol.11 , pp. 193-225
    • Yagihashi, S.1
  • 3
    • 0029954190 scopus 로고    scopus 로고
    • Pathologic alterations in the diabetic neuropathies of humans: A review
    • Dyck PJ, Giannini C (1996) Pathologic alterations in the diabetic neuropathies of humans: A review. J Neuropathol Exp Neurol 55: 1181-1193
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 1181-1193
    • Dyck, P.J.1    Giannini, C.2
  • 4
    • 0028095119 scopus 로고
    • Vascular factors in diabetic neuropathy
    • Tesfaye S, Malik R, Ward JD (1994) Vascular factors in diabetic neuropathy. Diabetologia 37: 847-854
    • (1994) Diabetologia , vol.37 , pp. 847-854
    • Tesfaye, S.1    Malik, R.2    Ward, J.D.3
  • 5
    • 0027318772 scopus 로고
    • Hyperglycemic pseudohypoxia and diabetic complications
    • Williamson JR, Chang K, Frangos M et al. (1993) Hyperglycemic pseudohypoxia and diabetic complications. Diabetes 42: 801-813
    • (1993) Diabetes , vol.42 , pp. 801-813
    • Williamson, J.R.1    Chang, K.2    Frangos, M.3
  • 6
    • 0031026509 scopus 로고    scopus 로고
    • Comparison of the effects of inhibitors of aldose reductase and sorbitol dehydrogenase on neurovascular function, nerve conduction and tissue polyol pathway metabolites in streptozotocin-diabetic rats
    • Cameron NE, Cotter MA, Basso M, Hohman TC (1997) Comparison of the effects of inhibitors of aldose reductase and sorbitol dehydrogenase on neurovascular function, nerve conduction and tissue polyol pathway metabolites in streptozotocin-diabetic rats. Diabetologia 40: 271-281
    • (1997) Diabetologia , vol.40 , pp. 271-281
    • Cameron, N.E.1    Cotter, M.A.2    Basso, M.3    Hohman, T.C.4
  • 7
    • 0031018374 scopus 로고    scopus 로고
    • Neuropathology and blood flow of nerve, spinal roots and dorsal root ganglia in longstanding diabetic rats
    • Berl
    • Sasaki H, Schmelzer JD, Zollman PJ, Low PA (1997) Neuropathology and blood flow of nerve, spinal roots and dorsal root ganglia in longstanding diabetic rats. Acta Neuropathol (Berl) 93: 118-128
    • (1997) Acta Neuropathol , vol.93 , pp. 118-128
    • Sasaki, H.1    Schmelzer, J.D.2    Zollman, P.J.3    Low, P.A.4
  • 8
    • 0029011459 scopus 로고
    • Impaired vasoreactivity to nitric oxide in experimental diabetic neuropathy
    • Kihara M, Low PA (1995) Impaired vasoreactivity to nitric oxide in experimental diabetic neuropathy. Exp Neurol 132: 180-185
    • (1995) Exp Neurol , vol.132 , pp. 180-185
    • Kihara, M.1    Low, P.A.2
  • 9
    • 0023744908 scopus 로고
    • The roles of essential fatty acids in the development of diabetic neuropathy and other complications of diabetes mellitus
    • Horrobin DF (1988) The roles of essential fatty acids in the development of diabetic neuropathy and other complications of diabetes mellitus. Prostaglandins Leukotrienes Essen Fatty Acids 31: 181-197
    • (1988) Prostaglandins Leukotrienes Essen Fatty Acids , vol.31 , pp. 181-197
    • Horrobin, D.F.1
  • 10
    • 0030930678 scopus 로고    scopus 로고
    • Role of neurotrophins in diabetic neuropathy and treatment with nerve growth factors
    • Tomlinson DR, Fernyhough P, Diemel LT (1997) Role of neurotrophins in diabetic neuropathy and treatment with nerve growth factors. Diabetes 46:S43-S49
    • (1997) Diabetes , vol.46
    • Tomlinson, D.R.1    Fernyhough, P.2    Diemel, L.T.3
  • 11
    • 0029826759 scopus 로고    scopus 로고
    • Nerve growth factor and diabetic neuropathy
    • Dyck PJ (1996) Nerve growth factor and diabetic neuropathy. Lancet 348: 1044-1045
    • (1996) Lancet , vol.348 , pp. 1044-1045
    • Dyck, P.J.1
  • 13
    • 0028091882 scopus 로고
    • Growth factors and diabetic neuropathy
    • Thomas PK (1994) Growth factors and diabetic neuropathy. Diabet Med 11: 732-739
    • (1994) Diabet Med , vol.11 , pp. 732-739
    • Thomas, P.K.1
  • 14
    • 0030969540 scopus 로고    scopus 로고
    • Effects of treatment of diabetic rats with human recombinant nerve growth factor on sciatic nerve conduction, Doppler flux and substance P levels
    • Maeda K, Fernyhough P Tomlinson DR (1997) Effects of treatment of diabetic rats with human recombinant nerve growth factor on sciatic nerve conduction, Doppler flux and substance P levels. Diabet Nutr Metab 10: 3-8
    • (1997) Diabet Nutr Metab , vol.10 , pp. 3-8
    • Maeda, K.1    Fernyhough, P.2    Tomlinson, D.R.3
  • 15
    • 0023628934 scopus 로고
    • Axonal transport and tissue contents of substance P in rats with long-term streptozotocin-diabetes. Effects of the aldose reductase inhibitor 'statil'
    • Robinson JP, Willars GB, Tomlinson DR, Keen P (1987) Axonal transport and tissue contents of substance P in rats with long-term streptozotocin-diabetes. Effects of the aldose reductase inhibitor 'statil'. Brain Res 426: 339-348
    • (1987) Brain Res , vol.426 , pp. 339-348
    • Robinson, J.P.1    Willars, G.B.2    Tomlinson, D.R.3    Keen, P.4
  • 16
    • 0024343878 scopus 로고
    • Essential fatty acid treatment-effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats
    • Tomlinson DR, Robinson JP, Compton AM, Keen P (1989) Essential fatty acid treatment-effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats. Diabetologia 32: 655-659
    • (1989) Diabetologia , vol.32 , pp. 655-659
    • Tomlinson, D.R.1    Robinson, J.P.2    Compton, A.M.3    Keen, P.4
  • 17
    • 0028609519 scopus 로고
    • Antioxidant properties of lipoic acid and its therapeutic effects in prevention of diabetes complications and cataracts
    • Packer L (1994) Antioxidant properties of lipoic acid and its therapeutic effects in prevention of diabetes complications and cataracts. Ann NY Acad Sci 738: 257-264
    • (1994) Ann NY Acad Sci , vol.738 , pp. 257-264
    • Packer, L.1
  • 18
    • 0029090976 scopus 로고
    • Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy
    • Nagamatsu M, Nickander KK, Schmelzer JD et al. (1995) Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy. Diabetes Care 18: 1160-1167
    • (1995) Diabetes Care , vol.18 , pp. 1160-1167
    • Nagamatsu, M.1    Nickander, K.K.2    Schmelzer, J.D.3
  • 19
    • 0031042744 scopus 로고    scopus 로고
    • α-Lipoic acid corrects neuropeptide deficits in diabetic rats via induction of trophic support
    • Garrett NE, Malcangio M, Dewhurst M, Tomlinson DR (1997) α-Lipoic acid corrects neuropeptide deficits in diabetic rats via induction of trophic support. Neurosci Lett 222: 191-194
    • (1997) Neurosci Lett , vol.222 , pp. 191-194
    • Garrett, N.E.1    Malcangio, M.2    Dewhurst, M.3    Tomlinson, D.R.4
  • 20
    • 0016186545 scopus 로고
    • Peripheral nerve structure and function in experimental diabetes
    • Sharma AK, Thomas PK (1974) Peripheral nerve structure and function in experimental diabetes. J Neurol Sci 23: 1-15
    • (1974) J Neurol Sci , vol.23 , pp. 1-15
    • Sharma, A.K.1    Thomas, P.K.2
  • 21
    • 0028118707 scopus 로고
    • Reduced sciatic nerve substance P and calcitonin gene-related peptide in rats with short-term diabetes or central hypoxaemia coexist with normal messenger RNA levels in the lumbar dorsal root ganglia
    • Brewster WJ, Diemel LT, Leach RM, Tomlinson DR (1994) Reduced sciatic nerve substance P and calcitonin gene-related peptide in rats with short-term diabetes or central hypoxaemia coexist with normal messenger RNA levels in the lumbar dorsal root ganglia. Neuroscience 58: 323-330
    • (1994) Neuroscience , vol.58 , pp. 323-330
    • Brewster, W.J.1    Diemel, L.T.2    Leach, R.M.3    Tomlinson, D.R.4
  • 22
    • 0022338161 scopus 로고
    • An immunoradiometric assay for the measurement of neuropeptide Y in plasma
    • Corder R, Lowry PJ (1985) An immunoradiometric assay for the measurement of neuropeptide Y in plasma. Peptides 6: 1195-1200
    • (1985) Peptides , vol.6 , pp. 1195-1200
    • Corder, R.1    Lowry, P.J.2
  • 23
    • 0027935410 scopus 로고
    • Deficits in sciatic nerve neuropeptide content coincide with a reduction in target tissue nerve growth factor mRNA in streptozotocin-diabetic rats; effects of insulin treatment
    • Fernyhough P, Diemel LT, Brewster WJ, Tomlinson DR (1994) Deficits in sciatic nerve neuropeptide content coincide with a reduction in target tissue nerve growth factor mRNA in streptozotocin-diabetic rats; effects of insulin treatment. Neuroscience 62: 337-344
    • (1994) Neuroscience , vol.62 , pp. 337-344
    • Fernyhough, P.1    Diemel, L.T.2    Brewster, W.J.3    Tomlinson, D.R.4
  • 24
    • 0025328370 scopus 로고
    • Endogenous levels of nerve growth factor (NGF) are altered in experimental diabetes mellitus: A possible role for NGF in the pathogenesis of diabetic neuropathy
    • Hellweg R, Hartung H-D (1990) Endogenous levels of nerve growth factor (NGF) are altered in experimental diabetes mellitus: a possible role for NGF in the pathogenesis of diabetic neuropathy. J Neurosci Res 26: 258-267
    • (1990) J Neurosci Res , vol.26 , pp. 258-267
    • Hellweg, R.1    Hartung, H.-D.2
  • 25
    • 0027976369 scopus 로고
    • Nerve growth factor administration protects against experimental diabetic sensory neuropathy
    • Apfel SC, Arezzo JC, Brownlee M, Federoff H, Kessler JA (1994) Nerve growth factor administration protects against experimental diabetic sensory neuropathy. Brain Res 634: 7-12
    • (1994) Brain Res , vol.634 , pp. 7-12
    • Apfel, S.C.1    Arezzo, J.C.2    Brownlee, M.3    Federoff, H.4    Kessler, J.A.5
  • 26
    • 0027976629 scopus 로고
    • Expression of neuropeptides in experimental diabetes; effects of treatment with nerve growth factor or brain-derived neurotrophic factor
    • Diemel LT, Brewster WJ, Fernyhough P, Tomlinson DR (1994) Expression of neuropeptides in experimental diabetes; effects of treatment with nerve growth factor or brain-derived neurotrophic factor. Mol Brain Res 21: 171-175
    • (1994) Mol Brain Res , vol.21 , pp. 171-175
    • Diemel, L.T.1    Brewster, W.J.2    Fernyhough, P.3    Tomlinson, D.R.4
  • 27
    • 0026342929 scopus 로고
    • Identification of nerve growth factor-responsive sequences within the 5 ' region of the bovine preprotachykinin gene
    • Gilchrist CA, Morrison CF, Chapman KE, Harmar AJ (1991) Identification of nerve growth factor-responsive sequences within the 5 ' region of the bovine preprotachykinin gene. DNA Cell Biol 10: 743-749
    • (1991) DNA Cell Biol , vol.10 , pp. 743-749
    • Gilchrist, C.A.1    Morrison, C.F.2    Chapman, K.E.3    Harmar, A.J.4
  • 29
    • 0028876777 scopus 로고
    • Altered neurotrophin mRNA in peripheral nerve and skeletal muscle of experimentally diabetic rats
    • Fernyhough P, Diemel LT, Brewster WJ, Tomlinson DR (1995) Altered neurotrophin mRNA in peripheral nerve and skeletal muscle of experimentally diabetic rats. J Neurochem 64: 1231-1237
    • (1995) J Neurochem , vol.64 , pp. 1231-1237
    • Fernyhough, P.1    Diemel, L.T.2    Brewster, W.J.3    Tomlinson, D.R.4
  • 31
    • 0020355905 scopus 로고
    • Neuropeptide Y (NPY)-like immunoreactivity in peripheral noradrenergic neurons and effects of NPY on sympathetic function
    • Lundberg JM, Terenius L, Hokfelt T et al. (1982) Neuropeptide Y (NPY)-like immunoreactivity in peripheral noradrenergic neurons and effects of NPY on sympathetic function. Acta Physiol Scand 116: 477-480
    • (1982) Acta Physiol Scand , vol.116 , pp. 477-480
    • Lundberg, J.M.1    Terenius, L.2    Hokfelt, T.3
  • 32
    • 0019944850 scopus 로고
    • Neuropeptide Y - A novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide
    • Tatemoto K, Carlquist M, Mutt V (1982) Neuropeptide Y - a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide. Nature 296: 659-660
    • (1982) Nature , vol.296 , pp. 659-660
    • Tatemoto, K.1    Carlquist, M.2    Mutt, V.3
  • 33
    • 0025763682 scopus 로고
    • Increased neuropeptide Y (NPY)-like immunoreactivity in rat sensory neurons following peripheral axotomy
    • Wakisaka S, Kajander KC, Bennett GJ (1991) Increased neuropeptide Y (NPY)-like immunoreactivity in rat sensory neurons following peripheral axotomy. Neurosci Lett 124: 200-203
    • (1991) Neurosci Lett , vol.124 , pp. 200-203
    • Wakisaka, S.1    Kajander, K.C.2    Bennett, G.J.3
  • 34
    • 0028865998 scopus 로고
    • Exogenous NT-3 mitigates the transganglionic neuropeptide Y response to sciatic nerve injury
    • Ohara S, Tantuwaya V, DiStefano PS, Schmidt RE (1995) Exogenous NT-3 mitigates the transganglionic neuropeptide Y response to sciatic nerve injury. Brain Res 699: 143-148
    • (1995) Brain Res , vol.699 , pp. 143-148
    • Ohara, S.1    Tantuwaya, V.2    DiStefano, P.S.3    Schmidt, R.E.4
  • 35
    • 0028927271 scopus 로고
    • Differential influence of nerve growth factor on neuropeptide expression in vivo: A novel role in peptide suppression in adult sensory neurons
    • Verge VMK, Richardson PM, Wiesenfeld-Hallin Z, Hökfelt T (1995) Differential influence of nerve growth factor on neuropeptide expression in vivo: a novel role in peptide suppression in adult sensory neurons. J Neurosci 15: 2081-2096
    • (1995) J Neurosci , vol.15 , pp. 2081-2096
    • Verge, V.M.K.1    Richardson, P.M.2    Wiesenfeld-Hallin, Z.3    Hökfelt, T.4
  • 36
    • 0021260538 scopus 로고
    • Neuropeptide Y (NPY) in PC12 phaeochromocytoma cultures: Responses to dexamethasone and nerve growth factor
    • Allen JM, Tischler AS, Lee YC, Bloom SR (1984) Neuropeptide Y (NPY) in PC12 phaeochromocytoma cultures: responses to dexamethasone and nerve growth factor. Neurosci Lett 46: 291-296
    • (1984) Neurosci Lett , vol.46 , pp. 291-296
    • Allen, J.M.1    Tischler, A.S.2    Lee, Y.C.3    Bloom, S.R.4
  • 37
    • 0027074265 scopus 로고
    • Identification of NGF-response element in the rat neuropeptide Y gene and induction of the binding proteins
    • Higuchi H, Nakano K, Miki N (1992) Identification of NGF-response element in the rat neuropeptide Y gene and induction of the binding proteins. Biochem Biophys Res Commun 189: 1553-1560
    • (1992) Biochem Biophys Res Commun , vol.189 , pp. 1553-1560
    • Higuchi, H.1    Nakano, K.2    Miki, N.3
  • 38
    • 0028278326 scopus 로고
    • Role of protein kinase C in mediating NGF effect on neuropeptide Y expression in PC12 cells
    • Balbi D, Allen JM (1994) Role of protein kinase C in mediating NGF effect on neuropeptide Y expression in PC12 cells. Brain Res Mol Brain Res 23: 310-316
    • (1994) Brain Res Mol Brain Res , vol.23 , pp. 310-316
    • Balbi, D.1    Allen, J.M.2
  • 39
    • 0028008694 scopus 로고
    • Effect of peripheral axotomy on expression of neuropeptide Y receptor mRNA in rat lumbar dorsal root ganglia
    • Zhang X, Wiesenfeld-Hallin Z, Hökfelt T (1994) Effect of peripheral axotomy on expression of neuropeptide Y receptor mRNA in rat lumbar dorsal root ganglia. Eur J Neurosci 6: 43-57
    • (1994) Eur J Neurosci , vol.6 , pp. 43-57
    • Zhang, X.1    Wiesenfeld-Hallin, Z.2    Hökfelt, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.