Cytokine and hepatitis B virus DNA Co-immunizations enhance cellular and humoral immune responses to the middle but not to the large hepatitis B virus surface antigen in mice

Hepatology

Volumn 28, Issue 1, 1998, Pages 202-210

  Geissler, Michael ^a,b,d   Schirmbeck, Reinhold ^c   Reimiann, Jorg ^c   Blum, Hubert E ^b   Wands, Jack R ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF ULM   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEPATITIS B SURFACE ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 4; TUMOR NECROSIS FACTOR ALPHA; VIRUS DNA; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HELPER CELL; HEPATITIS B; HUMORAL IMMUNITY; IMMUNE SYSTEM; IMMUNIZATION; IMMUNOBLOTTING; IMMUNOGENICITY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIMMUNOASSAY;

ANIMALS; ANTIBODY FORMATION; ANTIGENS, CD8; CYTOKINES; DNA; DNA, VIRAL; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; IMMUNITY, CELLULAR; IMMUNIZATION; INTERLEUKIN-2; MICE; MICE, INBRED BALB C; PLASMIDS; T-LYMPHOCYTES, CYTOTOXIC; T-LYMPHOCYTES, HELPER-INDUCER; VIRAL ENVELOPE PROTEINS;

EID: 0031808286     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510280126     Document Type: Article

References (4)

1. Purcell RH. The discovery of the hepatitis viruses. Gastroenterology 1993;104:955-963.
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3. Rehermann B, Fowler P, Sidney J, Person J, Redeker A, Brown M, Moss B, et al. The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis. J Exp Med 1995;181:1047-1058.
4. Nayersina R, Fowler P, Guilhot S, Missale G, Cemy A, Schlicht HJ, Vitiello A, et al. HLA A2 restricted cytotoxic T lymphocyte responses to multiple hepatitis B surface antigen epitopes during hepatitis B virus infection. I Immunol 1993;150:4659-4671.