Endothelial purine content: An alternative model for testing antibiotic solutions for intravenous use

Advances in Experimental Medicine and Biology

Volumn 431, Issue , 1998, Pages 827-831

  Vorbach, H ^a   Weigel, G ^b   Robibaro, B ^b   Reiter, M ^a   Hlousek, M ^a   Armbruster, C ^b   Griesmacher, A ^b   Georgopoulos, A ^a   Graninger, W ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; FLEROXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

CONFERENCE PAPER; DRUG EFFECT; DRUG TOLERANCE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; PHLEBITIS; PRIORITY JOURNAL; PURINE METABOLISM;

EID: 0031807761     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-5381-6_159     Document Type: Conference Paper

References (18)

1. Christ W, Lehnert T, Ulbrich B 1988. Specific toxicologic aspects of the fluoroquinolones. Rev Infect Dis 10 Suppl 1: 141-146.
2. Hooper DC, Wolfson JS 1991. Fluorquinolone antimicrobial agents. N Engl J Med 324: 384-394.
3. Forsgren A, Bredberg A, Riesbeck K 1989. New quinolones: in vitro effects as a potential source of clinical toxicity. Rev Infect Dis 11 Suppl. 5: 1382-1389.
4. Hooper DC, Wolfson JS. 1993. Quinolone Antimicrobial Agents, 2 nd. ed. American Society for Microbiology, Washington, DC.
5. Thorsteinsson SB, Bergan T, Johannesson G. Thorsteinsson HS. RohwedderR 1987 Tolerance of ciprofloxacin at injection site, systemic safety and effect on electroencephalogram. Chemotherapy 33:448-51.
6. Thorsteinsson SB, Rahm V, Bergan T 1989 Tolerance of intravenous ciprofloxacin. Scand J Infect Dis Suppl 60: 116-119.
7. Forgue ST. Shyu WC, Gleason CR, Pittman KA, Barbhaiya RH 1987 Pharmacokinetics of the novel cephalosporin cefepime (BMY - 28142) in rats and monkeys. Antimicrobial Agents and Chemotherapy 31: 799-804.
8. Griesmacher A, Weigel G, Windischbauer A, Mueller MM 1991 Purine metabolism in human endothelial cells. Int J Purine and Pyrimidine Res 2: 23-127.
9. Weigel G, Griesmacher A, Mueller MM 1991 Regulation of eicosanoid release in human umbilical vein endothelial cells. Thromb Res 62: 685-695.
10. Jaffe EA, Nachman RL, Becker CG, Minck CR 1973 Culture of human endothelial cells derived from umbilical veins. J Clin Invest 52: 2745-2756.
11. Haudenschild CC, Cotran RS, Gimbrone MA, Folkman J 1975 Fine structure of vascular endothelium in culture. J of Ultrastruct Res 50: 22-34.
12. Jaffe EA, Hoyer LW, Nachman RL 1973. Synthesis of antihaemophilic factor antigen by human endothelial cells. J Clin Invest 52: 2757-2763.
13. 2 synthesis by human endothelial cells. Arterioscler Thromb 12: 512-518.
14. Griesmacher A, Weigel G, David M. Schimke I, Mueller MM 1992 Influence of oxygen radicals generating agents on eicosanoid metabolism of human endothelial cells. Thromb Res 65: 721-731.
15. Weigel, G., A. Griesmacher, Toma, C., Leukauf, C., Schreiner, W., Wolner, E. 1993 The protective potency of two commonly used cardioplegic solutions on cultured endothelial cells exposed to free-oxygen radicals injury. Free Radical Biology & Medicine, 17: 577-585.
16. Burgmann H, Georgopoulos A, Graninger W, Koppensteiner R, Maca T, Minar E, Schneider B, Stümpften A, Ehringer H 1996 Tissue concentration of clindamycin and gentamicin near ischaemic ulcers with transvenous injection in Bier's arterial arrest. Lancet 368: 781-83.
17. Acevedo A. Schoop W, Schnell A, Toledo T 1990 Antibiotic treatment for diabetic foot. Advantages of intravenous regional route as alternative for systemic route. Rev Med Chi 118: 881-888.
18. Physicians'Desk Reference. 1994 Floxin® for intravenous infusion 48: 1352-1357.