Monte Carlo simulation of source-excited in vivo x-ray fluorescence measurements of heavy metals

Physics in Medicine and Biology

Volumn 43, Issue 6, 1998, Pages 1413-1428

  O'Meara, J M ^a   Chettle, D R ^a   McNeill, F E ^a   Prestwich, W V ^a   Svensson, C E ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HEAVY METAL;

ANALYTIC METHOD; ARTICLE; BODY BURDEN; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RADIATION SCATTERING; SIMULATION; SYSTEM ANALYSIS; X RAY FLUORESCENCE;

EID: 0031807379     PISSN: 00319155     EISSN: None     Source Type: Journal    
DOI: 10.1088/0031-9155/43/6/003     Document Type: Article

References (29)

1. Ahlgren L and Mattsson S 1979 An x-ray fluorescence technique for in vivo determination of lead concentration in a bone matrix Phys. Med. Biol. 24 136-45
2. Alm Carlsson G, Carlsson C A, Berggren K-F and Ribberfors R 1982 Calculation of scattering cross sections for increased accuracy in diagnostic radiology. I. Energy broadening of Compton-scattered photons Med. Phys. 9 868-79
3. Biggs F, Mendelsohn L B and Mann J B 1975 Hartree-Fock Compton profiles for the elements At. Data Nucl. Data Tables 16 201-309
4. Chan H P and Doi K 1988 Monte Carlo simulation in diagnostic radiology Monte Carlo Simulation in the Radiological Sciences ed R L Morin (Boca Raton, FL: CRC Press)
5. 2 - dioxane, isobutyric and n-butyric acids J. Chem. Phys. 58 4098-103
6. Gonsior B and Roth M 1983 Trace element analysis by particle and photon-induced x-ray emission spectroscopy Talanta 30 385-400
7. Goulding F S and Jaklevic J M 1977 XRF analysis - some sensitivity comparisons between charged-particle and photon excitation Nucl. Instrum. Methods 142 323-32
8. Goulding F S, Jaklevic J M, Jarrett B V and Landis DA 1971 Detector background and sensitivity of semiconductor x-ray fluorescence spectrometers Adv. X-Ray Anal. 15 470-82
9. He T, Gardner R P and Verghese K 1993 The Monte Carlo-library least-squares approach for energy-dispersive x-ray fluorescence analysis Appl. Radiat. Isot. 44 1381-8
10. Heath R L 1971 The application of high-resolution solid state detectors to x-ray spectrometry - a review Adv. X-Ray Anal. 15 1-35
11. Hodge H C 1973 A history of uranium poisoning (1824-1942) Uranium, Plutonium, Transplutonic Elements, Handbook of Experimental Pharmacology vol 36 (Berlin: Springer) pp 5-68
12. Hodge H C, Stannard J N and Hursh J B (ed) 1973 Uranium. Plutonium. Transplutonic Elements, Handbook of Experimental Pharmacology vol 36 (Berlin: Springer)
13. Hursh J B and Spoor N L 1973 Uranium data on man Uranium, Plutonium, Transplutonic Elements, Handbook of Experimental Pharmacology vol 36 (Berlin: Springer) pp 197-239
14. Kaufman L, Shosa D, Arbel A and Zender M 1982 Improved quantitation of low level tracers in x-ray fluorescent excitation analysis Nucl Instrum. Methods Phys. Res. 193 105-10
15. Lux I and Koblinger L 1991 Monte Carlo Particle Transport Methods: Neutron and Photon Calculations (Boca Raton, FL: CRC Press)
16. Meixner C H 1974 A Monte Carlo program for the calculation of γ-ray spectra for germanium detectors Nucl. Instrum. Methods Phys. Res. 119 521-6
17. O'Meara J M, Chettle D R and McNeill F E 1998 The validity of the coherent scatter peak normalization of x-ray intensities detected during in vivo x-ray fluorescence measurements of metals in bone Adv. X-Ray Anal. 41 at press
18. O'Meara J M, Chettle D R, McNeill F E and Webber C E 1997 The feasibility of measuring bone uranium concentrations in vivo using source-excited K x-ray fluorescence Phys. Med. Biol. 42 1109-20
19. Rindby A, Selin E, Berggren K-F and Ribberfors R 1982 Experimental and theoretical distributions of inelastically scattered radiation from aluminum in an EDXRF spectrometer (letter) Nucl. Instrum. Methods Phys. Res. 196 569-71
20. Seltzer S M 1981 Calculated response of intrinsic germanium detectors to narrow beams of photons with energies up to ≈300 keV Nucl. Instrum. Methods Phys. Res. 188 133-51
21. Somervaille L J, Chettle D R and Scott M C 1985 in vivo measurement of lead in bone using x-ray fluorescence Phys. Med. Biol. 30 929-43
22. Tartan A, Baraldi C, Felsteiner J and Casnati E 1991 Compton scattering profile for in vivo XRF techniques Phys. Med. Biol. 36 567-78
23. Tartan A, Fernandez J E, Casnati E, Baraldi C and Felsteiner J 1993 EDXRS modelling for in vivo trace element analysis by using the SHAPE code X-Ray Spectrom. 22 323-7
24. Todd A C, Chettle D R, Scott M R and Somervaille L J 1991 Monte Carlo modelling of in vivo x-ray fluorescence of lead in the kidney Phys. Med. Biol. 36 439-48
25. Varley B J, Kitching J E, Leo W, Miskin J, Moore R B, Wunsch K D, Decker R, Wollnik H and Siegert G 1981 Investigations of the response of germanium detectors to monoenergetic electron, positron and γ-ray beams Nucl. Instrum. Methods Phys. Res. 190 543-54
26. Wallace J D 1994 The Monte Carlo modelling of in vivo x-ray fluorescence measurement of lead in tissue Phys. Med. Biol. 39 1745-56
27. Weast R C and Astle M J 1981 CRC Handbook of Chemistry and Physics (Boca Raton, FL: CRC Press) p E-189
28. Wrenn M E, Durbin P W, Howard B, Lipsztein J, Rundo J, Still E T and Willis D L 1985 Metabolism of ingested U and Ra Health Phys. 48 601-33
29. Yuile C L 1973 Animal experiments Uranium, Plutonium, Transplutonic Elements, Handbook of Experimental Pharmacology vol 36 (Berlin: Springer) pp 165-96