Determination of thiopurine methyltransferase activity in erythrocytes using 6-thioguanine as the substrate

Advances in Experimental Medicine and Biology

Volumn 431, Issue , 1998, Pages 741-745

  Kroplin T ^a   Weyer, N ^a   Iven, H ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE; TIOGUANINE;

CONFERENCE PAPER; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; DRUG ERYTHROCYTE LEVEL; ENZYME ANALYSIS; ENZYME BINDING; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; METHYLATION; OXIDATION; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS;

EID: 0031807372     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-5381-6_142     Document Type: Conference Paper

References (5)

1. Weinshilboum RM, Sladek SL. Mercaptopurine pharmacogenetics: monogenetic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet 1980; 32: 651-62.
2. Tinel M, Berson A, Pessayre D, Letteron P, Cattoni MP, Horsmans Y, Larrey D. Pharmacogenetics of human erythrocyte thiopurine methyltransferase activity in a French population. Br J Clin Pharmacol 1991; 32: 729-34.
3. McLeod HL, Lin J-S, Pui C-H, Scott EP, Evans WE. Thiopurine methyltransferase activity in American white and black subjects. Clin Pharmacol Ther 1994; 55: 15-20.
4. Lynne Lennard, Helen J. Singleton. High-performance liquid chromatographic assay of human red blood cell thiopurine methyltransferase activity. J of Chromatography B 1994; 661: 25-33.
5. Weinshilboum RM, Raymond FA, Pazmino PA. Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties. Clin Chim Acta 1978; 85: 323-33.