Effects of sulfur mustard on cytokines released from cultured human epidermal keratinocytes

International Journal of Toxicology

Volumn 17, Issue 3, 1998, Pages 223-229

  Kurt, Ellen M ^a   Schafer, Robert J ^a   Arroyo, Carmen M ^a  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

HD; Interleukin 1; Interleukin 6; Interleukin 8; Keratinocytes; Sulfur mustard; TNF

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; MUSTARD GAS; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CYTOKINE RELEASE; DATA ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNE RESPONSE; KERATINOCYTE;

EID: 0031806745     PISSN: 10915818     EISSN: None     Source Type: Journal    
DOI: 10.1080/109158198226558     Document Type: Article

References (15)

1. Barker, J., Mitra, R., Griffiths, C., Dixit, V., and Nickoloff, B. 1991. Keratinocytes as initiators of inflammation. Lancet 337:211-214.
2. Breazeale, E., Lowry, J., Lankford, E., and Hunt, C. 1943. The Effects of Mustard on the Complement Titers of Rabbit Sera. U.S. Army Toxicology Research Division, Chemical Warfare Service, Report No. TDMR 528. DTIC No. AD-B960 393. Washington, DC: U.S. Army Research Division.
3. Casilla, R. P., Santai, C. T., and France, J. 1996. Cytokines as potential biomarkers of cutaneous resicant injury. FASEB. 10:A421.
4. Danneberg, A., and Tsuruta, J. 1993. Role of cytokines and reactive oxygen intermediates in the inflammatory response produced by sulfur mustard. Proc. Med. Defense Biosci. Rev. 1:57-66. ADA275667.
5. Graham, J., Bryant, M., and Braue, E. 1993. Effect of sulfur mustard on mast cells in hairless guinea pig skin. Proc. Med. Defense Biosci. Rev. 1:41-8. ADA275667.
6. Kupper, T. 1988. Interleukin 1 and other human keratinocyte cytokines: Molecular and functional characterization. Adv. Dermatol. 3:293-307.
7. Kupper, T. 1989. Mechanisms of cutaneous inflammation. Arch. Dermatol. 125:1406-1412.
8. Maeda, M., Van Schie, R., Yuksel, B., Greenough, A., Fanger, M., Guyre, P., and Lydyard, P. 1996. Differential expression of Fc receptors for IgG by monocytes and granulocytes from neonates and adults. Clin. Exp. Immunol. 103:343-347.
9. Nozaki, S., Feliciani, C., and Sauder, N. 1991. Keratinocyte cytokines. Adv. Dermatol. 7:83-100.
10. Opdenakker, G., and Van Damme, J. 1994. Cytokine-regulated proteases in autoimmune disease. Immunol. Today 15:103-107.
11. Papirmeister, B., Feister, A. J., and Robinson, S. I. 1991. Medical defense against mustard gas: Toxic mechanisms and pharmacological implications. Boca Raton, FL: CRC Press.
12. Pu, Y., Lin, P., Vaughan, F., and Bernstein, I. 1995. Appearance of interleukin-1α relates DNA interstrand cross-links and cytotoxicity in cultured human keratinocytes exposed to bis-(2-chloroethyl) Sulfide. J. Appl. Toxicol. 15:477-482.
13. Renshaw, B. 1946. Mechanisms in production of cutaneous injuries by sulfur and nitrogen mustards. In Chemical Warfare Agents and Related Chemical Problems Part III-VI. Summary Technical Report of Division of National Defense Research Committee of the Office of Scientific Research and Development. DTIC No. AD-234-249. Washington, DC: Office of Scientific Research and Development.
14. Schwartz, T., and Luger, T. 1992. Pharmacology of cytokines in the skin. In Pharmacology of the skin, ed. H. Mukhtar, pp. 283-313. Boca Raton, FL: CRC Press.
15. Zhang, Z., Riveire, J., and Monteiro-Riviere, N. A. 1995. Topical sulfur mustard induces changes in prostagladins and interleukin-1α in isolated perfused porcine skin. In Vitro Toxicol. 8:149-158.