Deposition and clearance of inhaled 18FDG powder in patients with chronic obstructive pulmonary disease

European Respiratory Journal

Volumn 11, Issue 6, 1998, Pages 1342-1348

  Yanai, M ^a   Hatazawa, J ^a   Ojima, F ^a   Sasaki, H ^a   Itoh, M ^a   Ido, T ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

18FDG powder; COPD; Deep inspiration; Deposition; Positron emission tomography

Indexed keywords

FLUORODEOXYGLUCOSE F 18; FREON;

ADULT; AEROSOL; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; HUMAN; INHALATIONAL DRUG ADMINISTRATION; LUNG CLEARANCE; LUNG DEPOSIT; LUNG FUNCTION TEST; MALE; POSITRON EMISSION TOMOGRAPHY; POWDER INHALER; PRIORITY JOURNAL; RESIDUAL VOLUME; TOTAL LUNG CAPACITY;

ADMINISTRATION, INHALATION; AGED; BRONCHI; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; LUNG; LUNG DISEASES, OBSTRUCTIVE; MALE; MIDDLE AGED; POWDERS; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED; TRACHEA;

EID: 0031806546     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.98.11061342     Document Type: Article

References (26)

1. 18FDG powder. J Comput Assist Tomogr 1990; 14: 175-181.
2. Svartengren M, Philipson K, Linnman L, Camner P. Regional deposition of particles in human lung after induced bronchoconstriction. Exp Lung Res 1986; 10: 223-233.
3. Pavia D, Thomson ML, Clarke SW, Shannon HS. Effect of lung function and mode of inhalation on penetration of aerosol into the human lung. Thorax 1977; 32: 194-197.
4. Dolovich MB, Sanchis J, Rossman C, Newhouse MT. Aerosol penetrance: a sensitive index of peripheral airways obstruction. J Appl Physiol 1976; 40: 468-471.
5. Newman SP, Morén F, Trofast E, Talaee N, Clarke SW. Deposition and clinical efficacy of terbutaline sulfate from Turbuhaler, a new multi-dose powder inhaler. Eur Respir J 1989; 2: 241-252.
6. Mitchell DM, Solomon MA, Tolfree SEJ, Short M, Spiro SG. Effect of particle size of bronchodilator aerosols on lung distribution and pulmonary function in patients with chronic asthma. Thorax 1987; 42: 457-461.
7. Sweeney TD, Skornik WA, Brain JD, Hatch V, Godleski JJ. Chronic bronchitis alters the pattern of aerosol deposition in the lung. Am J Respir Crit Care Med 1995; 151: 482-488.
8. Hughes JM, Rhodes CG, Brudin LH, Valind SO, Pantin C. Contribution of the positron camera to studies of regional lung structure and function. Eur J Nucl Med 1987; 13: S37-S41.
9. American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1995; 152: S77-S120.
10. 18]-fluoro-2-deoxy-D-glucose in man. J Nucl Med 1982; 23: 613-617.
11. 18]-fluoro-D-glucose suitable for inhalation to diagnose lung diseases by means of PET. Ann Nucl Med 1989; 3: 143-147.
12. Wollmer P, Rhodes CG, Hughes JM. Regional extravascular density and fractional blood volume of the lung in interstitial disease. Thorax 1984; 39: 286-293.
13. Phipps PR, Gonda I, Bailey DL, Borham P, Bautovich G, Anderson SD. Comparisons of planer and tomographic gamma scintigraphy to measure the penetration index of inhaled aerosols. Am Rev Respir Dis 1989; 139: 1516-1523.
14. Rhodes CG, Wollmer P, Fazio F, Jones T. Quantitative measurement of regional extravascular lung density using positron emission and transmission tomography. J Comput Assist Tomogr 1981; 5: 783-791.
15. Ryan G, Dolovich MB, Roberts RS, et al. Standardization of inhalation provocation tests: two techniques of aerosol generation and inhalation compared. Am Rev Respir Dis 1981; 123: 195-199.
16. Effros RM, Mason GR. Measurements of pulmonary epithelial permeability in vivo. Am Rev Respir Dis 1983; 127: S59-S65.
17. 99mTc-DTPA. Am Rev Respir Dis 1986; 134: 944-950.
18. 99mTc-DTPA from the bronchial mucosa. Am Rev Respir Dis 1989; 139: 1132-1138.
19. Iravani J, Melville GN. Mucociliary function in the respiratory tract as influenced by physiochemical factors. Pharmac Ther 1976; 2: 471-492.
20. 99mTc-DTPA in asthma. Am Rev Respir Dis 1989; 139: 1139-1143.
21. Honda I, Shimura S, Sasaki T, Sasaki H, Takishima T, Nakamura M. Airway mucosal permeability in chronic bronchitis and bronchial asthmatics with hypersecretion. Am Rev Respir Dis 1988; 137: 866-871.
22. Elwood RK, Kennedy S, Belzberg A, Hogg JC, Paré PD. Respiratory mucosa permeability in asthma. Am Rev Respir Dis 1983; 128: 523-527.
23. Wollmer P, Phodes CG, Allan RM, Maseri A, Fazio F. Regional extravascular lung density and fractional pulmonary blood volume in patients with chronic pulmonary venous hypertension. Clin Physiol 1983; 3: 241-256.
24. Kesten S, Elias M, Cartier A, Chapman KR. Patient handling of a multidose dry powder inhalation device for albuterol. Chest 1994; 105: 1077-1081.
25. Hansen NC, Andersen PB. Salbutamol powder inhaled from the Diskhaler compared to salbutamol as nebulizer solution in severe chronic airways obstruction. Respir Med 1995; 89: 175-179.
26. Perring S, Summers Q, Fleming JS, Nassim MA, Holgate ST. A new method of quantification of the pulmonary regional distribution of aerosols using combined CT and SPECT and its application to nedocromil sodium administered by metered dose inhaler. Br J Radiol 1994; 67: 46-53.