Phase separation of cholesterol in dimyristoyl phosphatidylserine cholesterol mixtures

Chemistry and Physics of Lipids

Volumn 92, Issue 1, 1998, Pages 71-77

  Bach, D ^a   Borochov, N ^a,b   Wachtel, E ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b HOLON INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Cholesterol solubility; Differential scanning calorimetry; Dimyristoyl phosphatidylserine; X ray diffraction

Indexed keywords

CHOLESTEROL; DIMYRISTOYLPHOSPHATIDYLSERINE; PHOSPHATIDYLSERINE; PHOSPHOLIPID; UNCLASSIFIED DRUG;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; HYDROGEN BOND; LIPID BILAYER; PHASE SEPARATION; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY; THERMOGRAPHY; X RAY DIFFRACTION;

EID: 0031806075     PISSN: 00093084     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-3084(98)00006-1     Document Type: Article

References (19)

1. Aranda-Espinoza H., Berman A., Dan N., Pincus P., Safran S. Interaction between inclusions embedded in membranes. Biophys. J. 71:1996;648-656.
2. Bach D. Differential scanning calorimetric study of mixtures of cholesterol with phosphatidylserine or galactocerebroside. Chem. Phys. Lipids. 35:1984;385-392.
3. 2+ ions. Biochim. Biophys. Acta. 979:1989;11-19.
4. Bach D., Wachtel E., Borochov N., Senisterra G., Epand R.M. Phase behaviour of heteroacid phosphatidylserines and cholesterol. Chem. Phys. Lipids. 63:1992;105-113.
5. Borochov N., Wachtel E., Bach D. Phase bahavior of mixtures of cholesterol and saturated phosphatidylglycerols. Chem. Phys. Lipids. 76:1995;85-92.
6. Cevc G., Watts A., Marsh D. Titration of the phase transition of phosphatidylserine bilayer membranes. Effects of pH, surface electrostatics, ion binding and head-group hydration. Biochemistry. 20:1981;4955-4965.
7. Cheetham J.J., Wachtel E., Bach D., Epand R. Role of the stereochemistry of the hydroxyl group of cholesterol and the formation of nonbilayer structures in phosphatidylethanolamines. Biochemistry. 28:1989;8928-8934.
8. Chen Z., Rand R.P. The influence of cholesterol on phospholipid membrane curvature and bending elasticity. Biophys. J. 73:1997;267-276.
9. Craven B.M. Crystal structure of cholesterol monohydrate. Nature. 260:1976;727-729.
10. Freeman R., Finean J.B. Cholesterol:lecithin association at molecular ratios of up to 2:1. Chem. Phys. Lipids. 14:1975;313-320.
11. 13C MAS NMR studies of crystalline cholesterol and lipid mixtures modeling atherosclerotic plaques. Biophys. J. 71:1996;2857-2868.
12. Hauser H., Paltauf F., Shipley G.G. Structure and thermotropic behavior of phosphatidylserine bilayer membranes. Biochemistry. 21:1982;1061-1067.
13. Hauser H. Some aspects of the phase behaviour of charged lipids. Biochim. Biophys. Acta. 772:1984;37-50.
14. Hauser H., Shipley G.G. Interactions of divalent cations with phosphatidylserine bilayer membranes. Biochemistry. 23:1984;34-41.
15. Knoll W., Schmidt G., Ibel K., Sackmann E. Small-angle neutron scattering study of lateral phase separation in dimyristoylphosphatidylcholine-cholesterol mixed membranes. Biochemistry. 24:1985;5240-5246.
16. Ladbrooke B.D., Williams R.M., Chapman D. Studies on lecithin-cholesterol-water interactions by differential scanning calorimetry and X-ray diffraction. Biochim. Biophys. Acta. 150:1968;333-340.
17. Loomis C.P., Shipley G.G., Small P.M. The phase behavior of hydrated cholesterol. J. Lipid Res. 20:1979;525-535.
18. Wachtel E., Bach D. X-ray diffraction study of cholesterol-phosphatidylserine mixtures. Biochim. Biophys. Acta. 922:1987;234-238.
19. Wachtel E., Borochov N., Bach D. The effect of protons or calcium ions on the phase behavior of phosphatidylserine-cholesterol mixtures. Biochim. Biophys. Acta. 1066:1991;63-69.