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Volumn 112, Issue 3, 1998, Pages 495-500

Deoxyspergualin preferentially inhibits the growth and maturation of anti-CD40-activated surface IgD+ B lymphocytes

Author keywords

B lymphocytes; Cellular differentiation; Cellular proliferation; Human; Immunomodulators

Indexed keywords

15 DEOXYSPERGUALIN; CD40 ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN M; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; METHYLDEOXYSPERGUALIN; MONOCLONAL ANTIBODY; SPERGUALIN DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0031805170     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00602.x     Document Type: Article
Times cited : (7)

References (31)
  • 1
    • 0027260855 scopus 로고
    • Synthesis and background chemistry of 15-deoxyspergualin. Immunomodulating drugs
    • Maeda K, Umeda Y, Sailno T. Synthesis and background chemistry of 15-deoxyspergualin. Immunomodulating drugs. Ann NY Acad Sci 1993; 685:123-204.
    • (1993) Ann NY Acad Sci , vol.685 , pp. 123-204
    • Maeda, K.1    Umeda, Y.2    Sailno, T.3
  • 2
    • 0022974099 scopus 로고
    • Allogeneic heart transplantation in the rat with a new antitumoral drug 15-deoxyspergualin
    • Walter P, Thies J, Harbauer G et al. Allogeneic heart transplantation in the rat with a new antitumoral drug 15-deoxyspergualin. Transplant Proc 1986; 18:1293-4.
    • (1986) Transplant Proc , vol.18 , pp. 1293-1294
    • Walter, P.1    Thies, J.2    Harbauer, G.3
  • 3
    • 0023551693 scopus 로고
    • Comparison of the new immunosuppressive agent 15-deoxyspergualin and cyclosporin A after highly allogeneic pancreas transplantation
    • Schubert G, Stoffregen C, Timmermann W et al. Comparison of the new immunosuppressive agent 15-deoxyspergualin and cyclosporin A after highly allogeneic pancreas transplantation. Transplant Proc 1987; 19:3978-9.
    • (1987) Transplant Proc , vol.19 , pp. 3978-3979
    • Schubert, G.1    Stoffregen, C.2    Timmermann, W.3
  • 4
    • 0025220079 scopus 로고
    • A novel rescue drug, 15-deoxyspergualin
    • Amemiya H, Suzuki S, Ota K et al. A novel rescue drug, 15-deoxyspergualin. Transplantation 1990; 49:337-43.
    • (1990) Transplantation , vol.49 , pp. 337-343
    • Amemiya, H.1    Suzuki, S.2    Ota, K.3
  • 5
    • 0028085299 scopus 로고
    • Pharmacokinetics of 15-deoxyspergualin studied in renal transplant patients receiving the drug during graft rejection
    • Ohlman S, Zilg H, Schindel F et al. Pharmacokinetics of 15-deoxyspergualin studied in renal transplant patients receiving the drug during graft rejection. Transplant Int 1994; 7:5-10.
    • (1994) Transplant Int , vol.7 , pp. 5-10
    • Ohlman, S.1    Zilg, H.2    Schindel, F.3
  • 6
    • 0028029788 scopus 로고
    • Immunosuppressant deoxyspergualin inhibits antigen processing in monocytes
    • Hoeger PH, Tepper MA, Faith A et al. Immunosuppressant deoxyspergualin inhibits antigen processing in monocytes. J Immunol 1994; 153:3908-16.
    • (1994) J Immunol , vol.153 , pp. 3908-3916
    • Hoeger, P.H.1    Tepper, M.A.2    Faith, A.3
  • 7
    • 0023371309 scopus 로고
    • Blastogenic responses and the release of interleukins 1 and 2 by spleen cells obtained from rat skin allograft recipients administered with 15-deoxyspergualin
    • Nemoto K, Abe F, Nakamura T et al. Blastogenic responses and the release of interleukins 1 and 2 by spleen cells obtained from rat skin allograft recipients administered with 15-deoxyspergualin. J Antibiotics 1987; 40:1062-4.
    • (1987) J Antibiotics , vol.40 , pp. 1062-1064
    • Nemoto, K.1    Abe, F.2    Nakamura, T.3
  • 8
    • 0025073514 scopus 로고
    • The immunosuppressive agent 15-deoxyspergualin induces tolerance and modulates MHC-antigen expression and interleukin-1 production in the early phase of rat allograft responses
    • Waaga AM, Urichs K, Krzysmanski M et al. The immunosuppressive agent 15-deoxyspergualin induces tolerance and modulates MHC-antigen expression and interleukin-1 production in the early phase of rat allograft responses. Transplant Proc 1990; 22:1613-4.
    • (1990) Transplant Proc , vol.22 , pp. 1613-1614
    • Waaga, A.M.1    Urichs, K.2    Krzysmanski, M.3
  • 9
    • 0025992209 scopus 로고
    • Immunosuppressive mechanism of 15-deoxyspergualin on sinusoidal lining cells in swine liver transplantation: Suppression of MHC class II antigens and interleukin-1 production
    • Takasu S, Sakagami K, Monsaki F et al. Immunosuppressive mechanism of 15-deoxyspergualin on sinusoidal lining cells in swine liver transplantation: suppression of MHC class II antigens and interleukin-1 production. J Surg Res 1991; 51:165-9.
    • (1991) J Surg Res , vol.51 , pp. 165-169
    • Takasu, S.1    Sakagami, K.2    Monsaki, F.3
  • 10
    • 0030163998 scopus 로고    scopus 로고
    • The immunosuppressant 1,5-deoxyspergualin reveals commonality between PreT and PreB cell differentiation
    • Wang B, Benooist C, Mathis D. The immunosuppressant 1,5-deoxyspergualin reveals commonality between PreT and PreB cell differentiation. J Exp Med 1996; 183:2427-36.
    • (1996) J Exp Med , vol.183 , pp. 2427-2436
    • Wang, B.1    Benooist, C.2    Mathis, D.3
  • 11
    • 0027184873 scopus 로고
    • 15-deoxyspergualin, a novel immunosuppressive drug: Studies of the mechanism of action
    • Tepper MA, Nadler S, Massucco C et al. 15-deoxyspergualin, a novel immunosuppressive drug: studies of the mechanism of action. Ann NY Acad Sci 1993; 685:136-47.
    • (1993) Ann NY Acad Sci , vol.685 , pp. 136-147
    • Tepper, M.A.1    Nadler, S.2    Massucco, C.3
  • 12
    • 0026526303 scopus 로고
    • Interaction of the immunosuppressant deoxyspergualin with a member of the Hsp70 family of heart shock proteins
    • Nadler SG, Tepper MA, Schacter B et al. Interaction of the immunosuppressant deoxyspergualin with a member of the Hsp70 family of heart shock proteins. Science 1992; 258:484-6.
    • (1992) Science , vol.258 , pp. 484-486
    • Nadler, S.G.1    Tepper, M.A.2    Schacter, B.3
  • 13
    • 0028230782 scopus 로고
    • Quantitation of the interaction of the immunosuppressant deoxyspergualin and analogs with Hsp70 and Hsp90
    • Nadeau K, Nadler SG, Saulnier M et al. Quantitation of the interaction of the immunosuppressant deoxyspergualin and analogs with Hsp70 and Hsp90. Biochem 1994; 33:2561-7.
    • (1994) Biochem , vol.33 , pp. 2561-2567
    • Nadeau, K.1    Nadler, S.G.2    Saulnier, M.3
  • 14
    • 0029038108 scopus 로고
    • Deoxyspergualin inhibits κ light chain expression in 70z/3 pre-B cells by blocking lipopolysaccharide-induced NF-kB activation
    • Tepper MA, Nadler SG, Esselstyn JM et al. Deoxyspergualin inhibits κ light chain expression in 70z/3 pre-B cells by blocking lipopolysaccharide-induced NF-kB activation. J Immunol 1995; 155:2427-36.
    • (1995) J Immunol , vol.155 , pp. 2427-2436
    • Tepper, M.A.1    Nadler, S.G.2    Esselstyn, J.M.3
  • 15
    • 0025979981 scopus 로고
    • Inhibition of antibody production by the immunosuppressive agent, 15-deoxyspergualin
    • Tepper MA, Petty B, Bursuker I et al. Inhibition of antibody production by the immunosuppressive agent, 15-deoxyspergualin. Transplant Proc 1991; 23:328-31.
    • (1991) Transplant Proc , vol.23 , pp. 328-331
    • Tepper, M.A.1    Petty, B.2    Bursuker, I.3
  • 16
    • 0026802043 scopus 로고
    • The suppressive effect of deoxyspergualin on the differentiation of human B lymphocyte maturing into immunoglobulin-producing cells
    • Morikawa K, Oseko F, Morikawa S. The suppressive effect of deoxyspergualin on the differentiation of human B lymphocyte maturing into immunoglobulin-producing cells. Transplantation 1991; 54:526-31.
    • (1991) Transplantation , vol.54 , pp. 526-531
    • Morikawa, K.1    Oseko, F.2    Morikawa, S.3
  • 17
    • 0028942191 scopus 로고
    • B-cell activation by crosslinking of surface IgM or ligation of CD40 involves alternative signal pathways and results in different B-cell phenotypes
    • Wortis HH, Teutsch M, Higer M et al. B-cell activation by crosslinking of surface IgM or ligation of CD40 involves alternative signal pathways and results in different B-cell phenotypes. Proc Natl Acad Sci USA 1995; 92:3348-52.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3348-3352
    • Wortis, H.H.1    Teutsch, M.2    Higer, M.3
  • 18
    • 0026563156 scopus 로고
    • Interleukin 10 and transforming growth factor cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A
    • Defrance T, Vanbervliet B, Briere F et al. Interleukin 10 and transforming growth factor cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A. J Exp Med 1992; 175:671-82.
    • (1992) J Exp Med , vol.175 , pp. 671-682
    • Defrance, T.1    Vanbervliet, B.2    Briere, F.3
  • 19
    • 0026026410 scopus 로고
    • Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen
    • Rousset F, Garcia H, Banchereau J. Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen. J Exp Med 1991; 173:705-10.
    • (1991) J Exp Med , vol.173 , pp. 705-710
    • Rousset, F.1    Garcia, H.2    Banchereau, J.3
  • 20
    • 0028087009 scopus 로고
    • CD40-activated surface IgD-positive lymphocytes constitute the long term IL-4-dependent proliferating B cell pool
    • Galibert L, Durand I, Banchereau J et al. CD40-activated surface IgD-positive lymphocytes constitute the long term IL-4-dependent proliferating B cell pool. J Immunol 1993; 152:22-29.
    • (1993) J Immunol , vol.152 , pp. 22-29
    • Galibert, L.1    Durand, I.2    Banchereau, J.3
  • 21
    • 0017357883 scopus 로고
    • Loss of surface IgD by human B lymphocytes during polyclonal activation
    • Preud'homme JL. Loss of surface IgD by human B lymphocytes during polyclonal activation. Eur J Immunol 1977; 7:191-3.
    • (1977) Eur J Immunol , vol.7 , pp. 191-193
    • Preud'homme, J.L.1
  • 23
    • 0027324003 scopus 로고
    • B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells
    • Nonoyama S, Hollenbaugh D, Aruffo A et al. B cell activation via CD40 is required for specific antibody production by antigen-stimulated human B cells. J Exp Med 1993; 178:1097-102.
    • (1993) J Exp Med , vol.178 , pp. 1097-1102
    • Nonoyama, S.1    Hollenbaugh, D.2    Aruffo, A.3
  • 24
    • 0029987922 scopus 로고    scopus 로고
    • The differentiation of human memory B cells into specific antibody-secreting cells is CD40 independent
    • Silvy A, Lagresle C, Bella C et al. The differentiation of human memory B cells into specific antibody-secreting cells is CD40 independent. Eur J Immunol 1996; 26:517-24.
    • (1996) Eur J Immunol , vol.26 , pp. 517-524
    • Silvy, A.1    Lagresle, C.2    Bella, C.3
  • 25
    • 0028198825 scopus 로고
    • Memory B cell development but not germinal center formation is impaired by in vitro blockade of CD40-CD40 ligand interaction
    • Gray D, Dullforce P, Jainandunsing S. Memory B cell development but not germinal center formation is impaired by in vitro blockade of CD40-CD40 ligand interaction. J Exp Med 1994; 180:141-55.
    • (1994) J Exp Med , vol.180 , pp. 141-155
    • Gray, D.1    Dullforce, P.2    Jainandunsing, S.3
  • 26
    • 0026800511 scopus 로고
    • Germinal centres in T-cell-dependent antibody responses
    • Liu Y-J, Johnson GD, Gordon J et al. Germinal centres in T-cell-dependent antibody responses. Immunol Today 1992; 13:17-21.
    • (1992) Immunol Today , vol.13 , pp. 17-21
    • Liu, Y.-J.1    Johnson, G.D.2    Gordon, J.3
  • 27
    • 0028797387 scopus 로고
    • Memory B lymphocytes in human tonsil do not express surface IgD
    • Nicholson IC, Brisco MJ, Zola H. Memory B lymphocytes in human tonsil do not express surface IgD. J Immunol 1995; 154:1105-13.
    • (1995) J Immunol , vol.154 , pp. 1105-1113
    • Nicholson, I.C.1    Brisco, M.J.2    Zola, H.3
  • 28
    • 0028174061 scopus 로고
    • Function and activation of NF-κ B in the immune system
    • Bacuerle PA, Henkel T. Function and activation of NF-κ B in the immune system. Annu Rev Immunol 1994; 12:141-79.
    • (1994) Annu Rev Immunol , vol.12 , pp. 141-179
    • Bacuerle, P.A.1    Henkel, T.2
  • 29
    • 0030443871 scopus 로고    scopus 로고
    • CD40, but not lipopolysaccharide and anti-IgM stimulation of primary B lymphocytes, lead to a persistent nuclear accumulation of Re1B
    • Neumann M, Wohlleben G, Chuvpilo S et al. CD40, but not lipopolysaccharide and anti-IgM stimulation of primary B lymphocytes, lead to a persistent nuclear accumulation of Re1B. J Immunol 1996; 157:4862-9.
    • (1996) J Immunol , vol.157 , pp. 4862-4869
    • Neumann, M.1    Wohlleben, G.2    Chuvpilo, S.3
  • 30
    • 0000908402 scopus 로고
    • Clinical spectrum of human chronic graft-vs.-host disease
    • Burakoff SJ, Deeg HJ, Ferrara J et al., eds. New York: Marcel Dekker
    • Atkinson K. Clinical spectrum of human chronic graft-vs.-host disease. In: Burakoff SJ, Deeg HJ, Ferrara J et al., eds. Graft-vs.-host disease: immunology, pathophysiology, and treatment. New York: Marcel Dekker, 1990:569-86.
    • (1990) Graft-vs.-host Disease: Immunology, Pathophysiology, and Treatment , pp. 569-586
    • Atkinson, K.1
  • 31
    • 0027197868 scopus 로고
    • Preclinical studies with 15-deoxyspergualin in various animal models for autoimmune diseases
    • Schorlemmer H-U, Dickneite G. Preclinical studies with 15-deoxyspergualin in various animal models for autoimmune diseases. Ann NY Acad Sci 1993; 685:155-74.
    • (1993) Ann NY Acad Sci , vol.685 , pp. 155-174
    • Schorlemmer, H.-U.1    Dickneite, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.