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Volumn 10, Issue 3, 1998, Pages 213-218

Recent randomized trials of chemoradiation in the management of locally advanced head and neck cancer

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CARBOPLATIN; CISPLATIN; FLUOROURACIL; FOLINIC ACID; HYDROXYUREA; METHOTREXATE; MITOMYCIN C;

EID: 0031804343     PISSN: 10408746     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001622-199805000-00007     Document Type: Article
Times cited : (43)

References (40)
  • 1
    • 0030270211 scopus 로고    scopus 로고
    • Treatment of head and neck cancer: The role of chemotherapy
    • Adelstein DJ, Tan EH, Lavertu P: Treatment of head and neck cancer: the role of chemotherapy. Crit Rev Oncol Hematol 1996, 24:97-116.
    • (1996) Crit Rev Oncol Hematol , vol.24 , pp. 97-116
    • Adelstein, D.J.1    Tan, E.H.2    Lavertu, P.3
  • 2
    • 0002058904 scopus 로고    scopus 로고
    • Chemoradiotherapy for head and neck cancer
    • Brockstein BE, Vokes EE: Chemoradiotherapy for head and neck • cancer. Updates: Principles Pract Oncol 1996, 10:1-19. This is a recent and comprehensive review of the use of chemotherapy and radiation together in the management of head and neck cancer. The University of Chicago phase II experience is summarized.
    • (1996) Updates: Principles Pract Oncol , vol.10 , pp. 1-19
    • Brockstein, B.E.1    Vokes, E.E.2
  • 5
    • 0028020603 scopus 로고
    • Placebo-controlled randomized trial of infusional fluorouracil during standard radiotherapy in locally advanced head and neck cancer
    • Browman GP, Cripps C, Hodson DI, Eapen L, Sathya J, Levine MN: Placebo-controlled randomized trial of infusional fluorouracil during standard radiotherapy in locally advanced head and neck cancer. J Clin Oncol 1994, 12:2648-2653.
    • (1994) J Clin Oncol , vol.12 , pp. 2648-2653
    • Browman, G.P.1    Cripps, C.2    Hodson, D.I.3    Eapen, L.4    Sathya, J.5    Levine, M.N.6
  • 6
    • 0023443418 scopus 로고
    • A randomized clinical trial to contrast radiotherapy with radiotherapy and methotrexate given synchronously in head and neck cancer
    • Gupta NK, Pointon RCS, Wilkinson PM: A randomized clinical trial to contrast radiotherapy with radiotherapy and methotrexate given synchronously in head and neck cancer. Clin Radiol 1987, 38:575-581.
    • (1987) Clin Radiol , vol.38 , pp. 575-581
    • Gupta, N.K.1    Pointon, R.C.S.2    Wilkinson, P.M.3
  • 7
    • 0018958364 scopus 로고
    • Combined bleomycin and radiotherapy in oral cancer
    • Shanta V, Krishnamurthi S: Combined bleomycin and radiotherapy in oral cancer. Clin Radiol 1980, 31:617-620.
    • (1980) Clin Radiol , vol.31 , pp. 617-620
    • Shanta, V.1    Krishnamurthi, S.2
  • 8
    • 0022360187 scopus 로고
    • Bleomycin and radiation therapy in squamous cell carcinoma of the upper aero-digestive tract: A phase III clinical trial
    • Vermund H, Kaalhus O, Winther F, Trausjø J, Thorud E, Harang R: Bleomycin and radiation therapy in squamous cell carcinoma of the upper aero-digestive tract: a phase III clinical trial. Int J Radiat Oncol Biol Phys 1985, 11:1877-1886.
    • (1985) Int J Radiat Oncol Biol Phys , vol.11 , pp. 1877-1886
    • Vermund, H.1    Kaalhus, O.2    Winther, F.3    Trausjø, J.4    Thorud, E.5    Harang, R.6
  • 9
    • 0023575637 scopus 로고
    • Combined radiotherapy and chemotherapy with bleomycin and methotrexate for advanced inoperable head and neck cancer: Update of a Northern California Oncology Group randomized trial
    • Fu KK, Phillips TL, Silverberg IJ, Jacobs C, Goffinet DR, Chun C, Friedman MA, Kohler M, McWhirter K, Carter SK: Combined radiotherapy and chemotherapy with bleomycin and methotrexate for advanced inoperable head and neck cancer: update of a Northern California Oncology Group randomized trial. J Clin Oncol 1987, 5:1410-1418.
    • (1987) J Clin Oncol , vol.5 , pp. 1410-1418
    • Fu, K.K.1    Phillips, T.L.2    Silverberg, I.J.3    Jacobs, C.4    Goffinet, D.R.5    Chun, C.6    Friedman, M.A.7    Kohler, M.8    McWhirter, K.9    Carter, S.K.10
  • 10
    • 0023856635 scopus 로고
    • Ten-year results of randomized trial comparing radiotherapy and concomitant bleomycin to radiotherapy alone in epidermoid carcinomas of the oropharynx: Experience of the European Organization for Research and Treatment of Cancer
    • Eschwege F, Sancho-Garnier H, Gerard JP, Madelain M, DeSaulty A, Jortay A, Cachin Y: Ten-year results of randomized trial comparing radiotherapy and concomitant bleomycin to radiotherapy alone in epidermoid carcinomas of the oropharynx: experience of the European Organization for Research and Treatment of Cancer. NCI Monogr 1988, 6:275-278.
    • (1988) NCI Monogr , vol.6 , pp. 275-278
    • Eschwege, F.1    Sancho-Garnier, H.2    Gerard, J.P.3    Madelain, M.4    DeSaulty, A.5    Jortay, A.6    Cachin, Y.7
  • 11
    • 0031032568 scopus 로고    scopus 로고
    • Chemotherapy as an adjunct to radiation in the treatment of squamous cell carcinoma of the head and neck: Results of the Yale mitomycin randomized trials
    • Haffty BG, Son YH, Papac R, Sasaki CT, Weissberg JB, Fischer D, •• Rockwell S, Sartorelli AC, Fischer JJ: Chemotherapy as an adjunct to radiation in the treatment of squamous cell carcinoma of the head and neck: results of the Yale mitomycin randomized trials. J Clin Oncol 1997, 15:268-276. This is a recent update of the Yale mitomycin C randomized trials conducted between 1980 and 1992. Most patients were treated postoperatively, and long term follow-up is presented. No overall survival benefit was observed, although other endpoints statistically favored concurrent chemoradiotherapy.
    • (1997) J Clin Oncol , vol.15 , pp. 268-276
    • Haffty, B.G.1    Son, Y.H.2    Papac, R.3    Sasaki, C.T.4    Weissberg, J.B.5    Fischer, D.6    Rockwell, S.7    Sartorelli, A.C.8    Fischer, J.J.9
  • 13
    • 0019197444 scopus 로고
    • Hydroxyurea and radiotherapy in head and neck cancer: Long term results of a double blind randomized prospective study
    • Stefani S, Chung TS: Hydroxyurea and radiotherapy in head and neck cancer: long term results of a double blind randomized prospective study [abstract]. Int J Radiat Oncol Biol Phys 1980, 6:1398.
    • (1980) Int J Radiat Oncol Biol Phys , vol.6 , pp. 1398
    • Stefani, S.1    Chung, T.S.2
  • 15
    • 0001359593 scopus 로고
    • Radiation alone versus radiation with weekly low dose cis-platinum in unresectable cancer of the head and neck
    • Edited by Fee WE Jr, Goepfert H, Johns ME, et al. Philadelphia: JB Lippincott
    • Haselow RE, Warshaw MG, Oken MM, Adams GL, Aughey JL, Cooper JS, Schuller DE, Jacobs CD: Radiation alone versus radiation with weekly low dose cis-platinum in unresectable cancer of the head and neck. Head and Neck Cancer, vol II. Edited by Fee WE Jr, Goepfert H, Johns ME, et al. Philadelphia: JB Lippincott; 1990:279-281.
    • (1990) Head and Neck Cancer , vol.2 , pp. 279-281
    • Haselow, R.E.1    Warshaw, M.G.2    Oken, M.M.3    Adams, G.L.4    Aughey, J.L.5    Cooper, J.S.6    Schuller, D.E.7    Jacobs, C.D.8
  • 17
    • 0030457015 scopus 로고    scopus 로고
    • Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced head and neck carcinoma: Final report of a randomized trial
    • Bachaud J-M, Cohen-Jonathan E, Alzieu C, David J-M, Serrano E, Daly-•• Schveitzer N: Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced head and neck carcinoma: final report of a randomized trial. Int J Radiat Oncol Biol Phys 1996, 36:999-1004. This is the final report of a phase III trial comparing postoperative radiation with postoperative radiation and weekly cisplatin. Locoregional control and survival were improved in the concurrent treatment group.
    • (1996) Int J Radiat Oncol Biol Phys , vol.36 , pp. 999-1004
    • Bachaud, J.-M.1    Cohen-Jonathan, E.2    Alzieu, C.3    David, J.-M.4    Serrano, E.5    Daly-Schveitzer, N.6
  • 19
    • 0027483035 scopus 로고
    • A randomized trial of radiation therapy compared to split course radiation therapy combined with mitomycin C and 5 fluorouracil as initial treatment for advanced laryngeal and hypopharyngeal squamous carcinoma
    • Keane TJ, Cummings BJ, O'Sullivan B, Payne D, Rawlinson E, MacKenzie R, Danjoux C, Hodson I: A randomized trial of radiation therapy compared to split course radiation therapy combined with mitomycin C and 5 fluorouracil as initial treatment for advanced laryngeal and hypopharyngeal squamous carcinoma. Int J Radiat Oncol Biol Phys 1993, 25:613-618.
    • (1993) Int J Radiat Oncol Biol Phys , vol.25 , pp. 613-618
    • Keane, T.J.1    Cummings, B.J.2    O'Sullivan, B.3    Payne, D.4    Rawlinson, E.5    MacKenzie, R.6    Danjoux, C.7    Hodson, I.8
  • 20
    • 0029002087 scopus 로고
    • Radiotherapy, combined with simultaneous chemotherapy with mitomycin C and bleomycin for inoperable head and neck cancer: Preliminary report
    • Smid L, Lesnicar H, Zakotnik B, Soba E, Budihna M, Furlan L, Zargi M, Rudolf Z: Radiotherapy, combined with simultaneous chemotherapy with mitomycin C and bleomycin for inoperable head and neck cancer: preliminary report. Int J Radiat Oncol Biol Phys 1995, 32:769-775.
    • (1995) Int J Radiat Oncol Biol Phys , vol.32 , pp. 769-775
    • Smid, L.1    Lesnicar, H.2    Zakotnik, B.3    Soba, E.4    Budihna, M.5    Furlan, L.6    Zargi, M.7    Rudolf, Z.8
  • 22
    • 0003372706 scopus 로고    scopus 로고
    • A phase III trial of hyperfractionated irradiation ± concurrent chemotherapy for locally advanced carcinoma of the head and neck: Superiority of combined modality treatment
    • Brizel DM, Albers MA, Fisher SR, Scher RL, Richtsmeier WJ, Clough R, George SL, Prosnitz LR: A phase III trial of hyperfractionated irradiation ± concurrent chemotherapy for locally advanced carcinoma of the head and neck: superiority of combined modality treatment [abstract]. Proc Am Soc Clin Oncol 1997, 16:384a.
    • (1997) Proc Am Soc Clin Oncol , vol.16
    • Brizel, D.M.1    Albers, M.A.2    Fisher, S.R.3    Scher, R.L.4    Richtsmeier, W.J.5    Clough, R.6    George, S.L.7    Prosnitz, L.R.8
  • 23
    • 0030931687 scopus 로고    scopus 로고
    • A phase III randomized trial comparing concurrent chemotherapy and radiotherapy with radiotherapy alone in resectable stage III and IV squamous cell head and neck cancer: Preliminary results
    • Adelstein DJ, Saxton JP, Lavertu P, Tuason L, Wood BG, Wanamaker JR. •• Eliachar I, Strome M, Van Kirk MA: A phase III randomized trial comparing concurrent chemotherapy and radiotherapy with radiotherapy alone in resectable stage III and IV squamous cell head and neck cancer: preliminary results. Head Week 1997, 19:567-575. This is a preliminary report of the author's randomized trial comparing multiagent chemoradiotherapy with radiation alone. Surgical resection was an integral part of management in patients with residual or recurrent disease after nonoperative treatment. Relapse-free survival, likelihood of distant metastases, and organ preservation were improved in the concurrent treatment group.
    • (1997) Head Week , vol.19 , pp. 567-575
    • Adelstein, D.J.1    Saxton, J.P.2    Lavertu, P.3    Tuason, L.4    Wood, B.G.5    Wanamaker, J.R.6    Eliachar, I.7    Strome, M.8    Van Kirk, M.A.9
  • 24
    • 0030987632 scopus 로고    scopus 로고
    • Management of the neck in a randomized trial comparing concurrent chemotherapy and radiotherapy with radiotherapy alone in resectable stage III and IV squamous cell head and neck cancer
    • Lavertu P, Adelstein DJ, Saxton JP, Secic M, Wanamaker JR, Eliachar I, Wood BG, Strome M: Management of the neck in a randomized trial comparing concurrent chemotherapy and radiotherapy with radiotherapy alone in resectable stage III and IV squamous cell head and neck cancer. Head Neck 1997, 19:559-566.
    • (1997) Head Neck , vol.19 , pp. 559-566
    • Lavertu, P.1    Adelstein, D.J.2    Saxton, J.P.3    Secic, M.4    Wanamaker, J.R.5    Eliachar, I.6    Wood, B.G.7    Strome, M.8
  • 25
    • 0011796349 scopus 로고
    • Long-term follow-up of a prospective randomized trial comparing simultaneous and sequential chemoradiotherapy for squamous cell head and neck cancer
    • Edited by Salmon SE. Philadelphia: JB Lippincott
    • Adelstein DJ, Sharan VM, Earle AS, Shah AC, Vlastou C, Haria CD, Damm C, Carter SG, Hines JD: Long-term follow-up of a prospective randomized trial comparing simultaneous and sequential chemoradiotherapy for squamous cell head and neck cancer. In Adjuvant Therapy of Cancer VII. Edited by Salmon SE. Philadelphia: JB Lippincott; 1993:82-91.
    • (1993) Adjuvant Therapy of Cancer VII , pp. 82-91
    • Adelstein, D.J.1    Sharan, V.M.2    Earle, A.S.3    Shah, A.C.4    Vlastou, C.5    Haria, C.D.6    Damm, C.7    Carter, S.G.8    Hines, J.D.9
  • 27
    • 0025778099 scopus 로고
    • Rationale for different chemotherapeutic and radiation therapy strategies in cancer management
    • Looney WB, Hopkins HA: Rationale for different chemotherapeutic and radiation therapy strategies in cancer management Cancer 1991, 67:1471-1483.
    • (1991) Cancer , vol.67 , pp. 1471-1483
    • Looney, W.B.1    Hopkins, H.A.2
  • 28
    • 0022455316 scopus 로고
    • A randomized trial of combined multidrug chemotherapy and radiotherapy in advanced squamous cell carcinoma of the head and neck
    • SECOG participants: A randomized trial of combined multidrug chemotherapy and radiotherapy in advanced squamous cell carcinoma of the head and neck. Eur J Surg Oncol 1986, 12:289-295.
    • (1986) Eur J Surg Oncol , vol.12 , pp. 289-295
  • 30
    • 9244264477 scopus 로고    scopus 로고
    • Five-year update of a randomized trial of alternating radiotherapy and chemotherapy compared with radiotherapy alone in treatment of unresectable squamous cell carcinoma of the head and neck
    • Merlano M, Benasso M, Corvȯ R, Rosso R, Vitale V, Blengio F, Numico G, •• Margarine G, Bonelli L, Santi L: Five-year update of a randomized trial of alternating radiotherapy and chemotherapy compared with radiotherapy alone in treatment of unresectable squamous cell carcinoma of the head and neck. J Natl Cancer Inst 1996, 88:583-589. This is a recent update of a trial comparing rapidly alternating radiation and chemotherapy with 5-fluorouracil and cisplatin to radiation therapy alone. At 5 years, the rapidly alternating chemoradiotherapy was superior for all measured endpoints.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 583-589
    • Merlano, M.1    Benasso, M.2    Corvo, R.3    Rosso, R.4    Vitale, V.5    Blengio, F.6    Numico, G.7    Margarine, G.8    Bonelli, L.9    Santi, L.10
  • 32
    • 0001054728 scopus 로고    scopus 로고
    • Superiority of chemoradiotherapy (CT-RT) vs radiotherapy (RT) in patients (PTS) with locally advanced nasopharyngeal cancer (NPC): Preliminary results of Intergroup (0099) (SWOG 8892, RTOG 8817, ECOG 2388) randomized study
    • Al-Sarraf M, LeBlanc M, Giri PGS, Fu K, Cooper J, Vuong T, Forastiere A. Adams G, Sakr W, Schuller D, Ensley J: Superiority of chemoradiotherapy (CT-RT) vs radiotherapy (RT) in patients (PTS) with locally advanced nasopharyngeal cancer (NPC): preliminary results of Intergroup (0099) (SWOG 8892, RTOG 8817, ECOG 2388) randomized study [abstract]. Proc Am Soc Clin Oncol 1996, 15:313.
    • (1996) Proc Am Soc Clin Oncol , vol.15 , pp. 313
    • Al-Sarraf, M.1    LeBlanc, M.2    Giri, P.G.S.3    Fu, K.4    Cooper, J.5    Vuong, T.6    Forastiere, A.7    Adams, G.8    Sakr, W.9    Schuller, D.10    Ensley, J.11
  • 34
    • 0000063051 scopus 로고    scopus 로고
    • A phase I study of weekly paclitaxel and cisplatin concurrent with postoperative radiation therapy for treatment of high-risk patients with squamous cell cancer of the head and neck
    • Flood WA, Lee DJ, Trotti A, DeConti R, Endicott J, Spencer S, Wheeler R, Taylor S IV, Forastiere AA: A phase I study of weekly paclitaxel and cisplatin concurrent with postoperative radiation therapy for treatment of high-risk patients with squamous cell cancer of the head and neck [abstract]. Proc Am Soc Clin Oncol 1996, 15:314.
    • (1996) Proc Am Soc Clin Oncol , vol.15 , pp. 314
    • Flood, W.A.1    Lee, D.J.2    Trotti, A.3    DeConti, R.4    Endicott, J.5    Spencer, S.6    Wheeler, R.7    Taylor IV, S.8    Forastiere, A.A.9
  • 36
    • 0030959666 scopus 로고    scopus 로고
    • Hyperfractionated radiation therapy and 5-fluorouracil, cisplatin and mitomycin-C (± granulocyte-colony stimulating factor) in the treatment of patients with locally advanced head and neck carcinoma
    • Abitbol AA, Sridhar KA, Lewin AA, Schwade JG, Raub W, Wolfson A, Gonzalez-Angulo C, Adessa A, Goodwin WJ, Markoe AM: Hyperfractionated radiation therapy and 5-fluorouracil, cisplatin and mitomycin-C (± granulocyte-colony stimulating factor) in the treatment of patients with locally advanced head and neck carcinoma. Cancer 1997, 80:266-276.
    • (1997) Cancer , vol.80 , pp. 266-276
    • Abitbol, A.A.1    Sridhar, K.A.2    Lewin, A.A.3    Schwade, J.G.4    Raub, W.5    Wolfson, A.6    Gonzalez-Angulo, C.7    Adessa, A.8    Goodwin, W.J.9    Markoe, A.M.10
  • 38
    • 0030746369 scopus 로고    scopus 로고
    • Efficacy of targeted supradose cisplatin and concomitant radiation therapy for advanced head and neck cancer: The Memphis experience
    • Robbins KT, Kumar P, Regine WF, Wong FSH, Weir AB, Flick P, Kun LE, • Palmer R, Murry T, Fontanesi J, et al.: Efficacy of targeted supradose cisplatin and concomitant radiation therapy for advanced head and neck cancer: the Memphis experience. Int J Radiat Oncol Biol Phys 1997, 38:263-271. This is a report of a large phase II trial using intra-arterial high-dose cisplatin and concurrent radiation therapy. Intriguing success in achieving locoregional control was observed. Phase III study is necessary.
    • (1997) Int J Radiat Oncol Biol Phys , vol.38 , pp. 263-271
    • Robbins, K.T.1    Kumar, P.2    Regine, W.F.3    Wong, F.S.H.4    Weir, A.B.5    Flick, P.6    Kun, L.E.7    Palmer, R.8    Murry, T.9    Fontanesi, J.10
  • 39
    • 0028852938 scopus 로고
    • An overview of randomized controlled trials of adjuvant chemotherapy in head and neck cancer
    • Munro AJ; An overview of randomized controlled trials of adjuvant chemotherapy in head and neck cancer. Br J Cancer 1995, 71:83-91.
    • (1995) Br J Cancer , vol.71 , pp. 83-91
    • Munro, A.J.1
  • 40
    • 0029868441 scopus 로고    scopus 로고
    • Adjuvant and adjunctive chemotherapy in the management of squamous cell carcinoma of the head and neck region: A meta-analysis of prospective and randomized trials
    • El-Sayed S, Nelson N: Adjuvant and adjunctive chemotherapy in the • management of squamous cell carcinoma of the head and neck region: a meta-analysis of prospective and randomized trials. J Clin Oncol 1996, 14:838-847. This is a recent meta-analysis demonstrating a significant survival improvement in patients treated with simultaneous chemotherapy and local management. The addition of chemotherapy also was noted to significantly increase the treatment morbidity.
    • (1996) J Clin Oncol , vol.14 , pp. 838-847
    • El-Sayed, S.1    Nelson, N.2


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