Immunocytochemical detection of cytokeratin positive cells in human bone marrow of gastric and colorectal cancer patients;Cytokeratinpositive zellen im knochenmark bei patienten mit gastralen und colorectalen carcinomen: Korrelation mit konventionellen prognosekriterien und dem klinischen verlauf

Zentralblatt fur Chirurgie

Volumn 123, Issue 5, 1998, Pages 520-524

  Leinung, St ^a,b   Schonfelder A ^a   Schonfelder M ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY HOSPITAL LEIPZIG   (Germany)

Author keywords

Colorectal cancer; Cytokeratin positive cells; Gastric cancer; Minimal residual disease

Indexed keywords

CYTOKERATIN;

ADULT; AGED; ARTICLE; CANCER STAGING; CLINICAL ARTICLE; COLORECTAL CANCER; FOLLOW UP; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; PROTEIN ISOLATION; RISK FACTOR; STOMACH CANCER;

ADULT; AGED; AGED, 80 AND OVER; BONE MARROW CELLS; BONE MARROW EXAMINATION; BONE MARROW NEOPLASMS; COLORECTAL NEOPLASMS; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOENZYME TECHNIQUES; KERATINS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; PROSPECTIVE STUDIES; RISK FACTORS; STATISTICS AS TOPIC; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 0031803089     PISSN: 0044409X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Broll R, Lembcke K, Stock C, Zingler M, Duchrow M, Schimmelpfennig H, Streik M, Müller G, Kujath P, Bruch HP (1996) Tumorzelldissemination in das Knochenmark und die Peritonealhöhle, Langenbecks Arch Chir 381: 51-58
2. Juhl H, Kalthoff H, Kruger U, Henne-Bruns D, Kremer B (1995) Immuncytologischer Nachweis mikrometastatischer Zellen bei Patienten mit gastrointestinalen Tumoren, Zentralbl Chir 120: 116-122
3. Leinung S (1997) Nachweis cytokeratinpositiver Zellen im Knochenmark bei Patienten mit gastralen und colorektalen Carzinomen - Korrelation mit konventionellen Prognosekriterien und dem klinischen Verlauf, Dissertation, Universität Leipzig
4. Lindemann F, Schlimok G, Dirschedl P et al (1992) Prognostic significance of micrometastatic tumor cells in bone marrow of colorectal cancer patients, Lancet 340: 685-689
5. Mansi JL, Berger U, Wilson P, Shearer R Coombes RC (1988) Detection of tumor cells in bone marrow of patients with prostatic carcinoma by immunocytochemical techniques, J Urol 139: 545-548
6. Mentges B, Bruckner R (1986) Das Kolonkarzinom: Prognostische Faktoren. Dtsch Med Wschr 111: 1790-1793
7. Meyer HJ, Jahne J, Weimann A Pichimayr R (1994) Chirurgische Therapie des Magencarcinoms - Indikation zur Splenektomie bei der Gastrektomie Chirurg 65: 437-440
8. Pantel K, Izbicki JR, Angstwurm M et al (1993) Immunocytological detection of bone marrow micrometastasis in operable non-small cell lung cancer, Cancer Res 53: 1027-1031
9. Pantel K, Schlimok G, Braun S, Kutter D, Lindemann F, Schaller G, Funke I, Izbicki JR, Rliethmüller G (1993) Differential expression of proliferation-assiated molecules in individual micrometastatic carcinoma cells. J Nat Cancer Inst, Vol 85, No. 17: 1419-1424
10. Pantel K, Schlimok G, Kutter D, Schaller G, Genz T, Wiebecke B, Backmann R, Funke I, Riethmüller G (1991) Frequent down regulation of major histiocompatibility class I antigen expression on individual micrometastatic carcinoma cells. Cancer Res 51: 4712-4715
11. Riethmüller G, Johnson J (1992) Monoclonal antibodies in the detection and therapy of micrometastatic epithelial cancer. Curr Opin Immunol 4: 647-655
12. Riesenberg R, Oberneder R, Kriegmair M et al (1993) Immunocytochemical double staining of cytokeratin and prostate spezific antigen in individual prostatic tumor cells. Histochemistry 99: 61-66
13. Schirren J (1995) Kommentar auf Anforderung der Schriftleitung, Der Chirurg 8: 785-786
14. Schlimok G, Funke I, Bock B, Schweiberer B, Witte J and Riethmüller G (1990) Epithelial tumor cells in bone marrow of patients with colorectal cancer: Immuncytochemical detection, phenotypic characterization and prognostic significance. J Clin Oncol 8: 831-837
15. Schlimok G, Funke I, Pantel K, Strobel, F, Lindemann F, WitteJ, Riethmüller G (1991) Micrometastatic tumor cells in bone marrow of patients with gastric cancer: methodological aspects of detection and prognostic significance. Eur J Cancer 27: 1561-1465
16. Schlimok G, Funke I, Holzmann B, Göttlinger G, Schmidt G, Häuser H, Swierkot S, Warnecke HH, Schneider B, Koprowski H, Riethmüller G (1987) Micrometastatic cancer cells in bone marrow: in vitro detection with anti-cytoceratin and in vivo labeling with anti-17-1A monoclonal antibodies. Proc Natl Acad Sci USA 84: 8672-76
17. Schlimok G, Riethmüller G (1990) Detection, characterization and tumorgenicity of disseminated tumor cells in human bone marrow. Sem Cancer Biol 1: 207-215
18. Schlimok G, Riethmüller G, Pantel K, Fackler-Schwalbe I, Loibner H (1994) Individual metastatic carcinoma cells in bone marrow of cancer patients are depleted by treatment with a monoclonal antibody direct against Lewis Y, 153. Gemeinsame Jahrestagung der Deutschen und der Österreichischen Gesellschaft für Hamatologie und Onkologie, Wien. Int J Cancer Res Treat 17 (suppl 2): I-XXVI+1-174
19. Silly H, Wilders-Truschnig M, Brezinschek HP, Schmid M, Kuss I, Mucher K, Stoger H, Samonigg H (1994) Varying amounts of tumor cells in bone marrow of patients with nonmetastatic colorectal cancer. Onkologie 17: 184-186
20. Suehiro S, Nagasue N, Ogawa Y, Sasaki Y, Hirose S, Yukaya H (1986) The negative effekt of splenectomy on the prognosis of gastric cancer. Am J Surg 148: 137