Prevalence and significance of anticardiolipin, anti-β2 glycoprotein I and anti-prothrombin antibodies in chronic hepatitis C

British Journal of Haematology

Volumn 101, Issue 3, 1998, Pages 468-474

  Leroy, Vincent ^a   Arvieux, Josiane ^a   Jacob, Marie Christine ^a   Maynard muet, Marianne ^a   Baud, Maryline ^a   Zarski, Jean Pierre ^a  

^a GRENOBLE UNIVERSITY HOSPITAL   (France)

Author keywords

2 glycoprotein I; Anticardiolipin; Hepatitis C virus; Interferon therapy; Prothrombin

Indexed keywords

ALPHA INTERFERON; BETA2 GLYCOPROTEIN 1; CARDIOLIPIN ANTIBODY; PROTHROMBIN; RECOMBINANT ALPHA2A INTERFERON;

ADULT; ANTIBODY TITER; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; DISEASE MARKER; DRUG EFFECT; FEMALE; HEPATITIS C; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; SEROPREVALENCE; SUBCUTANEOUS DRUG ADMINISTRATION; THROMBOCYTOPENIA;

ADULT; ANTIBODIES; ANTIBODIES, ANTICARDIOLIPIN; ANTIBODY SPECIFICITY; ANTIVIRAL AGENTS; BETA 2-GLYCOPROTEIN I; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLYCOPROTEINS; HEPATITIS C, CHRONIC; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERFERON-ALPHA; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PROTHROMBIN;

EID: 0031802982     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00722.x     Document Type: Article

References (27)

1. Abuaf, N., Lunel, F., Giral, P., Borotto, E., Laperche, S., Poupon, R., Opolon, P., Huraux, J.M. & Homberg, J.C. (1993) Non-organspecific autoantibodies associated with chronic C virus hepatitis. Journal of Hepatology, 18, 359-364.
2. Al-Saeed, A., Makris, M., Malia, R.G., Preston, F.E. & Greaves, M. (1994) The development of antiphospholipid antibodies in haemophilia is linked to infection with hepatitis C. British Journal of Haematology, 88, 845-848.
3. Arvieux, J., Darnige, L., Caron, C., Reber, G., Bensa, J.C. & Colomb, M.G. (1995) Development of an ELISA for autoantibodies to prothrombin showing their prevalence in patients with lupus anticoagulants. Thrombosis and Haemostasis, 74, 1120-1125.
4. 2-glycoprotein I as an antigen. Journal of Immunological Methods, 143, 223-229.
5. Becker, J.C., Winkler, B., Klingert, S. & Bröcker, E.B. (1994) Antiphospholipid syndrome associated with immunotherapy for patients with melanoma. Cancer, 73, 1621-1624.
6. Chedid, A., Chadalawada, K.R., Morgan, T.R., Moritz, T.E., Mendenhall, C.L., Hammond, J.B., Emblad, P.W., Cifuentes, D.C., Kwak, J.W.H., Gilman-Sachs, A. & Beaman, K.D. (1994) Phospholipid antibodies in alcoholic liver disease. Hepatology, 20, 1465-1471.
7. Galli, M., Finazzi, G. & Barbui, T. (1996) Thrombocytopenia in the antiphospholipid syndrome. British Journal of Haematology, 93, 1-5.
8. Gervais, A., Czernichow, B., Grunebaum, L., Wiesel, M.L., Auperin, A., Rival-Land, D., Gabanyi, J., Goldstein, L., Cazenave, J.P. & Doffoel, M. (1996) Anticorps sériques anticardiolipides chez les malades atteints de cirrhose alcoolique. Gastroentérologie Clinique et Biologique, 20, 736-742.
9. Gotoh, M. & Matsuda, J. (1995) Human immunodeficiency virus rather than hepatitis C virus infection is relevant to the development of an anticardiolipin antibody. American Journal of Hematology, 50, 220-222.
10. Hiramatsu, N., Hayashi, N., Katayama, K., Mochizuki, K., Kawanishi, Y., Kasahara, A., Fusamoto, H. & Kamada, T. (1994) Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C. Hepatology, 19, 1354-1359.
11. 2-glycoprotein I complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but not with infection. Lupus, 1, 75-81.
12. Knodell, R.G., Ishak, K.G., Black, W.C., Chen, T.S., Craig, R., Kaplowitz, N. & Kiernan, T.W. (1981) Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology, 1, 431-435.
13. Loizou, S., Cazabon, J.K., Walport, M.J., Tait, D. & So, A.K. (1997) Similarities of specificity and cofactor dependence in serum antiphospholipid antibodies from patients with human parvovirus B19 infection and from those with systemic lupus erythematosus. Arthritis and Rheumatism, 40, 103-108.
14. Love, P.E. & Santoro, S.A. (1990) Antiphospholipid antibodies: anticardiolipin and the lupus anticoagulant in systemic lupus erythematosus (SLE) and in non-SLE disorders. Annals of Internal Medicine, 112, 682-698.
15. Lunel, F. (1994) Hepatitis C virus and autoimmunity: fortuitous association or reality? Gastroenterology, 107, 1550-1555.
16. Matsuda, J., Saitoh, N., Gotoh, M., Gohchi, K., Tsukamoto, M., Syoji, S., Miyake, K. & Yamanaka, M. (1995) High prevalence of antiphospholipid antibodies and anti-thyroglobulin antibody in patients with hepatitis C virus infection treated with interferon-α. American Journal of Gastroenterology, 90, 1138-1141.
17. Mayet, W.J., Hess, G., Gerken, C., Rossol, S., Voth, R., Manns, M. & Meyer zum Büschenfelde, K.H. (1989) Treatment of chronic type B hepatitis with recombinant alpha Interferon induces autoantibodies not specific for autoimmune chronic hepatitis. Hepatology, 10, 24-28.
18. Pawlotsky, J.M., Ben Yahia, M., Andre, C., Voisin, M.C., Intrator, L., Roudot-Thoraval, F., Deforges, L., Duvoux, C., Zafrani, E.S., Duval, J. & Dhumeaux, D. (1994) Immunological disorders in C virus chronic active hepatitis: a prospective case-control study. Hepatology, 19, 841-848.
19. Piette, J.C. (1996) 1996 diagnostic and classification criteria for the antiphospholipid/cofactors syndrome: a 'mission impossible'? Lupus, 5, 354-363.
20. Pivetti, S., Novarino, A., Merico, R, Bertero, M.T., Brunetto, M.R., Bonino, F. & Caligaris-Cappio, F. (1996) High prevalence of autoimmune phenomena in hepatitis C virus antibody positive patients with lymphoproliferative and connective tissue disorders. British Journal of Haematology, 95, 204-211.
21. Prieto, J., Yuste, J.R., Beloqui, O., Civeira, M,P., Riezu, J.I., Aguirre, B. & Sangro, B. (1996) Anticardiolipin antibodies in chronic hepatitis C: implication of hepatitis C virus as the cause of the antiphospholipid syndrome. Hepatology, 23, 199-204.
22. 2-glycoprotein I plasma levels. Journal of Hepatology, 21, 1086-1091.
23. Reber, G., Arvieux, J., Comby, E., Degenne, D., de Moerloose, P., Sanmarco, M. & Potron, G. (1995) Multicenter evaluation of nine commercial kits for the quantitation of anticardiolipin antibodies. Thrombosis and Haemostasis, 73, 444-452.
24. Roubey, R.A.S. (1994) Autoantibodies to phospholipid-binding plasma proteins: a new view of lupus anticoagulants and other 'antiphospholipid' autoantibodies. Blood, 84, 2854-2867.
25. Roubey, R.A.S. (1996) Antigenic specificities of antiphospholipid autoantibodies: implications for clinical laboratory testing and diagnosis of the antiphospholipid syndrome. Lupus, 5, 425-430.
26. Saracco, G., Touscoz, A., Durazzo, M., Rosina, E. Donegani, E., Chiandussi, L., Gallo, V., Petrino, R., De Micheli, A.G., Solinas, A., Deplano, A., Tocco, A., Cossu, P.A., Pintus, C., Verme, G. & Rizzetto, M. (1990) Autoantibodies and response to α-interferon in patients with chronic viral hepatitis. Journal of Hepatology, 11, 339-343.
27. Violi, F., Ferro, D., Basili, S., Artini, M., Valesini, G., Levrero, M. & Cordova, C. (1995) Increased rate of thrombin generation in hepatitis C virus cirrhotic patients: relationship to venous thrombosis. Journal of Investigative Medicine, 43, 550-554.