A simple alternate substrate test can help determine the aqueous or bilayer location of binding sites for hydrophobic ligands/substrates on membrane proteins

Chemical Research in Toxicology

Volumn 11, Issue 6, 1998, Pages 703-707

  Morgenstern, Ralf ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLIZING ENZYME;

ARTICLE; BINDING KINETICS; DETOXIFICATION; DRUG BINDING SITE; ENZYME ACTIVE SITE; ENZYME LOCALIZATION; ENZYME SUBSTRATE COMPLEX; HYDROPHOBICITY; MEMBRANE BINDING; PROTEIN LIPID INTERACTION; XENOBIOTIC METABOLISM;

ANIMALS; BINDING SITES; LIGANDS; LIPID BILAYERS; MALE; MEMBRANE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY;

FELIS CATUS;

EID: 0031802936     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx980013e     Document Type: Article

References (12)

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