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Volumn 11, Issue 6, 1998, Pages 639-650

Oxidation of serotonin by superoxide radical: Implications to neurodegenerative brain disorders

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; METHAMPHETAMINE; SEROTONIN; SUPEROXIDE;

EID: 0031802887     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx970185w     Document Type: Article
Times cited : (108)

References (70)
  • 1
    • 0030915855 scopus 로고    scopus 로고
    • Oxidative stress hypothesis in Alzheimer's disease
    • Markesbery, W. R. (1997) Oxidative stress hypothesis in Alzheimer's disease. Free Radical Biol. Med. 23, 134-137.
    • (1997) Free Radical Biol. Med. , vol.23 , pp. 134-137
    • Markesbery, W.R.1
  • 2
    • 0026635461 scopus 로고
    • Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease
    • Jenner, P., Dexter, D. T., Sian, J., Schapira, A. H. V., and Marsden C. D. (1992) Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. Ann. Neurol. 32, S83-S87.
    • (1992) Ann. Neurol. , vol.32
    • Jenner, P.1    Dexter, D.T.2    Sian, J.3    Schapira, A.H.V.4    Marsden, C.D.5
  • 3
    • 0025309904 scopus 로고
    • Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia-reperfusion-induced injury in gerbil brain
    • Oliver, C. N., Starke-Reed, P. E., Stadtman, E. R., Liu, G. J., Carney, J. M., and Floyd, R. A. (1990) Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia-reperfusion-induced injury in gerbil brain. Proc. Natl Acad. Sci. U.S.A. 87, 5144-5147.
    • (1990) Proc. Natl Acad. Sci. U.S.A. , vol.87 , pp. 5144-5147
    • Oliver, C.N.1    Starke-Reed, P.E.2    Stadtman, E.R.3    Liu, G.J.4    Carney, J.M.5    Floyd, R.A.6
  • 4
    • 0028986577 scopus 로고
    • Methamphetamine-induced serotonin neurotoxicity is mediated by Superoxide radicals
    • Hirata, H., Ladenheim, B., Rothman, R. B., Epstein, C., and Cadet, J. L. (1995) Methamphetamine-induced serotonin neurotoxicity is mediated by Superoxide radicals. Brain Res. 677, 345-347.
    • (1995) Brain Res. , vol.677 , pp. 345-347
    • Hirata, H.1    Ladenheim, B.2    Rothman, R.B.3    Epstein, C.4    Cadet, J.L.5
  • 6
    • 0026773281 scopus 로고
    • Oxygen radicals as key mediators in neurological disease: Fact or fiction?
    • Halliwell, B. (1992) Oxygen radicals as key mediators in neurological disease: Fact or fiction? Ann. Neurol. 32, S10-S15.
    • (1992) Ann. Neurol. , vol.32
    • Halliwell, B.1
  • 7
    • 0026470907 scopus 로고
    • Ischemia-induced extracellular release of serotonin plays a role in CA1 neuronal cell death in rats
    • Globus, M. Y.-T., Wester, P., Busto, R., and Dietrich, W. D. (1992) Ischemia-induced extracellular release of serotonin plays a role in CA1 neuronal cell death in rats. Stroke 23, 1595-1601.
    • (1992) Stroke , vol.23 , pp. 1595-1601
    • Globus, M.Y.-T.1    Wester, P.2    Busto, R.3    Dietrich, W.D.4
  • 9
    • 0024315672 scopus 로고
    • Effects of transient global cerebral ischemia on striatal extracellular dopamine, serotonin and their metabolites
    • Phebus, L. A., and Clemens, J. A. (1989) Effects of transient global cerebral ischemia on striatal extracellular dopamine, serotonin and their metabolites. Life Sci. 44, 1335-1342.
    • (1989) Life Sci. , vol.44 , pp. 1335-1342
    • Phebus, L.A.1    Clemens, J.A.2
  • 10
    • 0021707433 scopus 로고
    • Elevation of extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
    • [10) Benveniste, H., Drejer, J., Schouboe, A., and Diemer, N. H. (1984) Elevation of extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43, 1369-1374.
    • (1984) J. Neurochem. , vol.43 , pp. 1369-1374
    • Benveniste, H.1    Drejer, J.2    Schouboe, A.3    Diemer, N.H.4
  • 11
    • 0021023811 scopus 로고
    • Nerve terminal damage in cerebral ischemia: Greater susceptibility of catecholamine nerve terminals relative to serotonin nerve terminals
    • Weinberger, J., Cohen, G., and Nieves-Rosa, J. (1983) Nerve terminal damage in cerebral ischemia: Greater susceptibility of catecholamine nerve terminals relative to serotonin nerve terminals. Stroke 14, 986-989.
    • (1983) Stroke , vol.14 , pp. 986-989
    • Weinberger, J.1    Cohen, G.2    Nieves-Rosa, J.3
  • 12
    • 0025909198 scopus 로고
    • Relationship between free radical production and lipid peroxidation during ischemia-reperfusion injury in rat brain
    • Sakamoto, A., Ohnishi, S. T., Ohnishi, T., and Ogawa, R. (1991) Relationship between free radical production and lipid peroxidation during ischemia-reperfusion injury in rat brain. Brain Res. 554, 186-192.
    • (1991) Brain Res. , vol.554 , pp. 186-192
    • Sakamoto, A.1    Ohnishi, S.T.2    Ohnishi, T.3    Ogawa, R.4
  • 13
    • 0028040278 scopus 로고
    • Human copper-zinc Superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia
    • Yang, G. Y., Chan, P. H., Chen, J., Carlson, E., Chen, S. F., Weinstein, P., Epstein, C. J., and Kamii, H. (1994) Human copper-zinc Superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia. Stroke 25, 165-170.
    • (1994) Stroke , vol.25 , pp. 165-170
    • Yang, G.Y.1    Chan, P.H.2    Chen, J.3    Carlson, E.4    Chen, S.F.5    Weinstein, P.6    Epstein, C.J.7    Kamii, H.8
  • 14
    • 0022654023 scopus 로고
    • Mononucleotide metabolism in the rat brain after transient ischemia
    • Onodera, H., Iijima, K., and Kogure, K. (1986) Mononucleotide metabolism in the rat brain after transient ischemia. J. Neurochem. 46, 1704-1710.
    • (1986) J. Neurochem. , vol.46 , pp. 1704-1710
    • Onodera, H.1    Iijima, K.2    Kogure, K.3
  • 16
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous sytem
    • Choi, D. W. (1988) Glutamate neurotoxicity and diseases of the nervous sytem. Neuron 1, 623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 17
    • 0027221998 scopus 로고
    • NMDA-dependent Superoxide production and neurotoxicity
    • Lafon-Cazal, M., Pletri, S., Calcusi, M., and Bockaert J. (1993) NMDA-dependent Superoxide production and neurotoxicity. Nature 364, 535-537.
    • (1993) Nature , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pletri, S.2    Calcusi, M.3    Bockaert, J.4
  • 18
    • 0001477438 scopus 로고
    • Methamphetamine and amphetamine neurotoxicity
    • Chang, L. W., and Dyer, R. S., Eds. Marcel Dekker, New York
    • Bowyer, J. F., and Holson, R. R. (1995) Methamphetamine and amphetamine neurotoxicity. In Handbook of Neurotoxicology (Chang, L. W., and Dyer, R. S., Eds.) pp 845-870, Marcel Dekker, New York.
    • (1995) Handbook of Neurotoxicology , pp. 845-870
    • Bowyer, J.F.1    Holson, R.R.2
  • 20
    • 0001355426 scopus 로고
    • Neurotoxicity of methamphetamine-related drugs and cocaine
    • Chang, L. W., and Dyer, R. S., Eds. Marcel Dekker, New York
    • Seiden, L. S., and Sabol, K. E. (1995) Neurotoxicity of methamphetamine-related drugs and cocaine. In Handbook of Neurotoxicology (Chang, L. W., and Dyer, R. S., Eds.) pp 825-843, Marcel Dekker, New York.
    • (1995) Handbook of Neurotoxicology , pp. 825-843
    • Seiden, L.S.1    Sabol, K.E.2
  • 21
    • 0022503780 scopus 로고
    • α-Methyltyrosine blocks methamphetamine-induced degeneration in the rat somatosensory cortex
    • Commins, D. L., and Seiden, L.-S. (1986) α-Methyltyrosine blocks methamphetamine-induced degeneration in the rat somatosensory cortex. Brain Res. 365, 15-20.
    • (1986) Brain Res. , vol.365 , pp. 15-20
    • Commins, D.L.1    Seiden, L.-S.2
  • 22
    • 0024342811 scopus 로고
    • Methamphetamine-induced neuronal damage: A possible role for free radicals
    • De Vito, M. J., and Wagner, G. C. (1989) Methamphetamine-induced neuronal damage: A possible role for free radicals. Neuropharmacology 28, 1145-1150.
    • (1989) Neuropharmacology , vol.28 , pp. 1145-1150
    • De Vito, M.J.1    Wagner, G.C.2
  • 23
    • 0021959287 scopus 로고
    • Role of the dopamine uptake carrier in the neurochemical response to methamphetamine: Effects of amfonelic acid
    • Schmidt, C. J., and Gibb, J. W. (1985) Role of the dopamine uptake carrier in the neurochemical response to methamphetamine: Effects of amfonelic acid. Eur. J. Pharmacol. 109, 73-80.
    • (1985) Eur. J. Pharmacol. , vol.109 , pp. 73-80
    • Schmidt, C.J.1    Gibb, J.W.2
  • 24
    • 0021074142 scopus 로고
    • Fluoxetine increases long-lasting neostriatal dopamine depletion after administration of d-methamphetamine and d-amphetamine
    • Ricaurte, G. A., Fuller, R. W., Perry, K. W., Seiden, L. S., and Schuster, C. R. (1983) Fluoxetine increases long-lasting neostriatal dopamine depletion after administration of d-methamphetamine and d-amphetamine. Neuropharmacology 22, 1165-1169.
    • (1983) Neuropharmacology , vol.22 , pp. 1165-1169
    • Ricaurte, G.A.1    Fuller, R.W.2    Perry, K.W.3    Seiden, L.S.4    Schuster, C.R.5
  • 25
    • 0021813964 scopus 로고
    • Cerebral norepinephrine depletion enhances recovery after brain ischemia
    • Busto, R., Harik, S. L, Yoshida, S., Scheinberg, P., and Ginsberg, M. D. (1985) Cerebral norepinephrine depletion enhances recovery after brain ischemia. Ann. Neurol. 18, 329-336.
    • (1985) Ann. Neurol. , vol.18 , pp. 329-336
    • Busto, R.1    Harik, S.L.2    Yoshida, S.3    Scheinberg, P.4    Ginsberg, M.D.5
  • 26
    • 0022004746 scopus 로고
    • Nerve terminal damage in cerebral ischemia: Protective effects of alpha-methyl-para-tyrosine
    • Weinberger, J., Nieves-Rosa, J., and Cohen, G. (1985) Nerve terminal damage in cerebral ischemia: protective effects of alpha-methyl-para-tyrosine. Stroke 16, 864-870.
    • (1985) Stroke , vol.16 , pp. 864-870
    • Weinberger, J.1    Nieves-Rosa, J.2    Cohen, G.3
  • 28
    • 0025285757 scopus 로고
    • α-Methyl-p-tyrosine pretreatment partially prevents methamphetamine-induced neurotoxin formation
    • Axt, K., Commins, D. L., Vosmer, G., and Seiden, L. S. (1990) α-Methyl-p-tyrosine pretreatment partially prevents methamphetamine-induced neurotoxin formation. Brain Res. 515, 269-276.
    • (1990) Brain Res. , vol.515 , pp. 269-276
    • Axt, K.1    Commins, D.L.2    Vosmer, G.3    Seiden, L.S.4
  • 29
    • 0029844831 scopus 로고    scopus 로고
    • The role of monoamine metabolism in oxidative glutamate toxicity
    • Maher, P., and Davis, J. B. (1996) The role of monoamine metabolism in oxidative glutamate toxicity. J. Neurosci. 16, 6394-6401.
    • (1996) J. Neurosci. , vol.16 , pp. 6394-6401
    • Maher, P.1    Davis, J.B.2
  • 30
    • 0023141541 scopus 로고
    • 5,6-Dihydroxytryptamine, a serotonergic neurotoxin, is formed endogenously in the rat brain
    • Commins, D. L., Axt, K. J., and Seiden, L.-S. (1987) 5,6-Dihydroxytryptamine, a serotonergic neurotoxin, is formed endogenously in the rat brain. Brain Hes. 403, 7-14.
    • (1987) Brain Hes. , vol.403 , pp. 7-14
    • Commins, D.L.1    Axt, K.J.2    Seiden, L.-S.3
  • 31
    • 0021282148 scopus 로고
    • Formation of 6-hydroxy-dopamine in caudate nucleus of the rat brain after a single large dose of methylamphetamine
    • Seiden, L. S., and Vosmer, G. (1984) Formation of 6-hydroxy-dopamine in caudate nucleus of the rat brain after a single large dose of methylamphetamine. Pharmacol. Biochem. Behav. 21, 29-31.
    • (1984) Pharmacol. Biochem. Behav. , vol.21 , pp. 29-31
    • Seiden, L.S.1    Vosmer, G.2
  • 32
    • 0022834136 scopus 로고
    • Failure to detect 6-hydroxydopamine in rat striatum after the dopamine releasing drugs dexamphetamine, methylamphetamine and MPTP
    • Rollema, H., De Vries, J. B., Westerink, B. H. C., Van Putten, F. M., and Horn, A. S. (1986) Failure to detect 6-hydroxydopamine in rat striatum after the dopamine releasing drugs dexamphetamine, methylamphetamine and MPTP. Eur. J. Pharmacol. 132, 65-69.
    • (1986) Eur. J. Pharmacol. , vol.132 , pp. 65-69
    • Rollema, H.1    De Vries, J.B.2    Westerink, B.H.C.3    Van Putten, F.M.4    Horn, A.S.5
  • 33
    • 0027362024 scopus 로고
    • Absence of 6-hydroxydopamine in the rat brain after treatment with stimulants and other dopaminergic agents: A mass fragmentographic study
    • Karoum, F., Chrapusta, S. J., Egan, M. F., and Wyatt, R. J. (1993) Absence of 6-hydroxydopamine in the rat brain after treatment with stimulants and other dopaminergic agents: a mass fragmentographic study. J. Neurochem. 61, 1369-1375.
    • (1993) J. Neurochem. , vol.61 , pp. 1369-1375
    • Karoum, F.1    Chrapusta, S.J.2    Egan, M.F.3    Wyatt, R.J.4
  • 34
    • 0030938603 scopus 로고    scopus 로고
    • 5-Hydroxy-3-(ethylamino) -2-oxindole is not formed in rat brain following a neurotoxic dose of methamphetamine: Evidence that methamphetamine does not induce hydroxyl radical-mediated oxidation of serotonin
    • Yang, Z., Wrona, M. Z., and Dryhurst, G. (1997) 5-Hydroxy-3-(ethylamino) -2-oxindole is not formed in rat brain following a neurotoxic dose of methamphetamine: Evidence that methamphetamine does not induce hydroxyl radical-mediated oxidation of serotonin. J. Neurochem. 68, 1929-1941.
    • (1997) J. Neurochem. , vol.68 , pp. 1929-1941
    • Yang, Z.1    Wrona, M.Z.2    Dryhurst, G.3
  • 35
    • 0028831990 scopus 로고
    • Hydroxyl radical-mediated oxidation of serotonin: Potential insights into the neurotoxicity of methamphetamine
    • Wrona, M. Z., Yang, Z., McAdams, M., O'Connor-Coates, S., and Dryhurst, G. (1995) Hydroxyl radical-mediated oxidation of serotonin: Potential insights into the neurotoxicity of methamphetamine. J. Neurochem. 64, 1390-1400.
    • (1995) J. Neurochem. , vol.64 , pp. 1390-1400
    • Wrona, M.Z.1    Yang, Z.2    McAdams, M.3    O'Connor-Coates, S.4    Dryhurst, G.5
  • 36
    • 0022398587 scopus 로고
    • Hydroxyl radical attack on dopamine
    • Slivka, A., and Cohen, G. (1985) Hydroxyl radical attack on dopamine. J. Biol. Chem. 260, 15466-15472.
    • (1985) J. Biol. Chem. , vol.260 , pp. 15466-15472
    • Slivka, A.1    Cohen, G.2
  • 37
    • 0003386362 scopus 로고
    • Synthesis and reactivity of the putative neurotoxin tryptamine-4,5-dione
    • Singh, S., Wrona, M. Z., and Dryhurst, G. (1992) Synthesis and reactivity of the putative neurotoxin tryptamine-4,5-dione. Bioorg. Chem. 20, 189-203.
    • (1992) Bioorg. Chem. , vol.20 , pp. 189-203
    • Singh, S.1    Wrona, M.Z.2    Dryhurst, G.3
  • 38
    • 0027444724 scopus 로고
    • 7-S-Glutathionyl-tryptamine-4,5-dione: A possible aberrant metabolite of serotonin
    • Wong, K.-S., Goyal, R. N., Wrona, M. Z., Blank, C. L., and Dryhurst, G. (1993) 7-S-Glutathionyl-tryptamine-4,5-dione: A possible aberrant metabolite of serotonin. Biochem. Pharmacol. 46, 1637-1652.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 1637-1652
    • Wong, K.-S.1    Goyal, R.N.2    Wrona, M.Z.3    Blank, C.L.4    Dryhurst, G.5
  • 39
    • 0011840248 scopus 로고
    • Influence of glutathione on the electrochemical and enzymatic oxidation of serotonin
    • Wrona, M. Z., Singh, S., and Dryhurst, G. (1995) Influence of glutathione on the electrochemical and enzymatic oxidation of serotonin. J. Electroanal. Chem. 382, 41-51.
    • (1995) J. Electroanal. Chem. , vol.382 , pp. 41-51
    • Wrona, M.Z.1    Singh, S.2    Dryhurst, G.3
  • 40
    • 0025163848 scopus 로고
    • Electrochemical oxidation of 5-hydroxytryptamine in aqueous solution at physiological pH
    • Wrona, M. Z., and Dryhurst, G. (1990) Electrochemical oxidation of 5-hydroxytryptamine in aqueous solution at physiological pH. Bioorg. Chem. 18, 291-317.
    • (1990) Bioorg. Chem. , vol.18 , pp. 291-317
    • Wrona, M.Z.1    Dryhurst, G.2
  • 42
    • 0024410219 scopus 로고
    • Characterization of free radical generation by xanthine oxidase
    • Kappusamy, P., and Zweier, J. L. (1989) Characterization of free radical generation by xanthine oxidase. J. Biol. Chem. 264, 9880-9884.
    • (1989) J. Biol. Chem. , vol.264 , pp. 9880-9884
    • Kappusamy, P.1    Zweier, J.L.2
  • 43
    • 0024430918 scopus 로고
    • The role of iron in oxygen radical mediated lipid peroxidation
    • Minotti, G., and Aust, S. D. (1989) The role of iron in oxygen radical mediated lipid peroxidation. Chem.-Biol. Interact. 71, 1-19.
    • (1989) Chem.-Biol. Interact. , vol.71 , pp. 1-19
    • Minotti, G.1    Aust, S.D.2
  • 44
    • 0026597915 scopus 로고
    • Redox cycling of iron and lipid peroxidation
    • Minotti, G., and Aust, S. D. (1992) Redox cycling of iron and lipid peroxidation. Lipids 27, 219-226.
    • (1992) Lipids , vol.27 , pp. 219-226
    • Minotti, G.1    Aust, S.D.2
  • 45
    • 0023278116 scopus 로고
    • Desferrioxamine (desferal) and superoxide free radicals: Formation of an enzyme-dam aging nitroxide
    • Davies, M. J., Donkor, R., Dunster, C. A., Gee, C. A., Jonas, S., and Willson, R. L. (1987) Desferrioxamine (desferal) and superoxide free radicals: Formation of an enzyme-dam aging nitroxide. Biochem. J. 246, 725-729.
    • (1987) Biochem. J. , vol.246 , pp. 725-729
    • Davies, M.J.1    Donkor, R.2    Dunster, C.A.3    Gee, C.A.4    Jonas, S.5    Willson, R.L.6
  • 46
    • 0013785558 scopus 로고
    • Reactivity and function of sulfhydryl groups in horse liver alcohol dehydrogenase
    • Li, T., and Vallee, B. L. (1965) Reactivity and function of sulfhydryl groups in horse liver alcohol dehydrogenase. Biochemistry 4, 1195-1202.
    • (1965) Biochemistry , vol.4 , pp. 1195-1202
    • Li, T.1    Vallee, B.L.2
  • 47
    • 33847087052 scopus 로고
    • Does Superoxide ion oxidize catechol, α-tocopherol, and ascorbic acid by direct electron transfer?
    • Nanni, E. J., Stallings, M. D., and Sawyer, D. T. (1980) Does Superoxide ion oxidize catechol, α-tocopherol, and ascorbic acid by direct electron transfer? J. Am. Chem. Soc. 102, 4481-4485.
    • (1980) J. Am. Chem. Soc. , vol.102 , pp. 4481-4485
    • Nanni, E.J.1    Stallings, M.D.2    Sawyer, D.T.3
  • 49
    • 0022380031 scopus 로고
    • Mechanism and products of autoxidation of 5,7-dihydroxytryptamine
    • Sinhababu, A. K., and Borchardt, R. T. (1985) Mechanism and products of autoxidation of 5,7-dihydroxytryptamine. J. Am. Chem. Soc. 107, 7618-7627.
    • (1985) J. Am. Chem. Soc. , vol.107 , pp. 7618-7627
    • Sinhababu, A.K.1    Borchardt, R.T.2
  • 50
    • 0025055451 scopus 로고
    • Autoxidation of the serotonergic neurotoxin 5,7-dihydroxytryptamine
    • Tabatabaie, T., Wrona, M. Z., and Dryhurst, G. (1990) Autoxidation of the serotonergic neurotoxin 5,7-dihydroxytryptamine. J. Med, Chem. 33, 667-672.
    • (1990) J. Med, Chem. , vol.33 , pp. 667-672
    • Tabatabaie, T.1    Wrona, M.Z.2    Dryhurst, G.3
  • 52
    • 0023236818 scopus 로고
    • Histochemical evaluation of glutathione in brain
    • Slivka, A., Mytilineou, C. A., and Cohen, G. (1987) Histochemical evaluation of glutathione in brain. Brain Res. 409, 275-284.
    • (1987) Brain Res. , vol.409 , pp. 275-284
    • Slivka, A.1    Mytilineou, C.A.2    Cohen, G.3
  • 53
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell, B. (1992) Reactive oxygen species and the central nervous system. J. Neurochem. 59, 1609-1623.
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 54
    • 0024780029 scopus 로고
    • Neurotoxic properties of a serotonin oxidation product: Possible role in Alzheimer's disease
    • Iqbal, K., Wisniewski, H. M., and Winblad, B., Eds. A. R. Liss, Inc., New York
    • Volicer, L., Chen, J.-C., Crino, P. B., Vogt, B. A., Fishman, J., Rubins, J., Schnepper, P. W., and Wolfe, N. (1989) Neurotoxic properties of a serotonin oxidation product: Possible role in Alzheimer's disease. In Alzheimer's Disease and Related Disorders (Iqbal, K., Wisniewski, H. M., and Winblad, B., Eds.) pp 453-465, A. R. Liss, Inc., New York.
    • (1989) Alzheimer's Disease and Related Disorders , pp. 453-465
    • Volicer, L.1    Chen, J.-C.2    Crino, P.B.3    Vogt, B.A.4    Fishman, J.5    Rubins, J.6    Schnepper, P.W.7    Wolfe, N.8
  • 55
    • 0024851612 scopus 로고
    • Neurotoxic effects of partially oxidized serotonin: Tryptamine-4,5-dione
    • Crino, P. B., Vogt, B. A, Chen, J.-C., and Volicer, L. (1989) Neurotoxic effects of partially oxidized serotonin: Tryptamine-4,5-dione. Brain Res. 504, 247-257.
    • (1989) Brain Res. , vol.504 , pp. 247-257
    • Crino, P.B.1    Vogt, B.A.2    Chen, J.-C.3    Volicer, L.4
  • 56
    • 0026611138 scopus 로고
    • Neurochemical changes in the rat brain after intraventricular administration of tryptamine-4,5-dione
    • Chen, J.-C., Schnepper, P. W., To, A., and Volicer, L. (1992) Neurochemical changes in the rat brain after intraventricular administration of tryptamine-4,5-dione. Neuropharmacology 31, 215-219.
    • (1992) Neuropharmacology , vol.31 , pp. 215-219
    • Chen, J.-C.1    Schnepper, P.W.2    To, A.3    Volicer, L.4
  • 57
    • 0030886119 scopus 로고    scopus 로고
    • Irreversible inhibition of mitochondrial complex I by 7-(2-aminoethyl)-3,4-dihydro-5-hydroxy-2H-1,4-benzothiazine-3-carboxlic acid (DHBT-1) : A putative nigral endotoxin of relevance to Parkinson's disease
    • Li, H., and Dryhurst, G. (1997) Irreversible inhibition of mitochondrial complex I by 7-(2-aminoethyl)-3,4-dihydro-5-hydroxy-2H-1,4-benzothiazine-3-carboxlic acid (DHBT-1) : A putative nigral endotoxin of relevance to Parkinson's disease. J. Neurochem. 69, 1530-1541.
    • (1997) J. Neurochem. , vol.69 , pp. 1530-1541
    • Li, H.1    Dryhurst, G.2
  • 58
    • 0024561602 scopus 로고
    • Evidence for the presence of red and white cells within "platelet" aggregates formed in whole blood
    • Joseph, R., Welch, K. M. A., D'Andrea, G., and Riddle, J. M. (1989) Evidence for the presence of red and white cells within "platelet" aggregates formed in whole blood. Thromb. Res. 53, 485-491.
    • (1989) Thromb. Res. , vol.53 , pp. 485-491
    • Joseph, R.1    Welch, K.M.A.2    D'Andrea, G.3    Riddle, J.M.4
  • 59
    • 0002662074 scopus 로고
    • Platelet secretion
    • Colman, R. W., Hirsch, J., Marder, V. J., and Salzman, E. W., Eds. J. B. Lippincott Co., PA
    • Hohnsen, H. (1987) Platelet secretion. In Thrombosis and Hemostasis. 2nd ed. (Colman, R. W., Hirsch, J., Marder, V. J., and Salzman, E. W., Eds.) pp 606-617, J. B. Lippincott Co., PA.
    • (1987) Thrombosis and Hemostasis. 2nd Ed. , pp. 606-617
    • Hohnsen, H.1
  • 60
    • 0019246538 scopus 로고
    • Behavior of the blood-brain barrier towards biogenic amines in experimental cerebral ischemia
    • Hervonen, H., Steinwall, O., Spatz, M., and Klatzo, I. (1980) Behavior of the blood-brain barrier towards biogenic amines in experimental cerebral ischemia. Adv. Exp. Med. Biol. 131, 295-305.
    • (1980) Adv. Exp. Med. Biol. , vol.131 , pp. 295-305
    • Hervonen, H.1    Steinwall, O.2    Spatz, M.3    Klatzo, I.4
  • 61
    • 0025747980 scopus 로고
    • Platelet secretory products may contribute to neuronal injury
    • Joseph, R., Tsering, C., Grunfeld, S., and Welch, K. M. A. (1992) Platelet secretory products may contribute to neuronal injury Stroke 22, 1448-1451.
    • (1992) Stroke , vol.22 , pp. 1448-1451
    • Joseph, R.1    Tsering, C.2    Grunfeld, S.3    Welch, K.M.A.4
  • 62
    • 0023103843 scopus 로고
    • Platelet-derived growth factor is a mitogen for glial but not for neuronal rat brain cells in vitro
    • Besnard, F., Perraud, F., Sensenbrenner, M., and Labourdette, G. (1987) Platelet-derived growth factor is a mitogen for glial but not for neuronal rat brain cells in vitro. Neurosci. Lett. 73, 287-292.
    • (1987) Neurosci. Lett. , vol.73 , pp. 287-292
    • Besnard, F.1    Perraud, F.2    Sensenbrenner, M.3    Labourdette, G.4
  • 63
    • 0028118593 scopus 로고
    • Modulation of intracellular formation of reactive oxygen intermediates in peritoneal macrophages and microglia/brain macrophages by protentofylline
    • Banati, R. B., Schubert, P., Rothe, G., Gehrmann, J., Rudolphi, K., Valet, G., and Kreutzberg, G. W. (1994) Modulation of intracellular formation of reactive oxygen intermediates in peritoneal macrophages and microglia/brain macrophages by protentofylline. J. Cereb. Blood Flow Metab. 14, 145-149.
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 145-149
    • Banati, R.B.1    Schubert, P.2    Rothe, G.3    Gehrmann, J.4    Rudolphi, K.5    Valet, G.6    Kreutzberg, G.W.7
  • 64
    • 0023642584 scopus 로고
    • Production of Superoxide anions by a CNS macrophage, the microglia
    • Colton, C., and Gilbert, D. (1987) Production of Superoxide anions by a CNS macrophage, the microglia. FEES Lett. 223, 284-288.
    • (1987) FEES Lett. , vol.223 , pp. 284-288
    • Colton, C.1    Gilbert, D.2
  • 65
    • 0029143298 scopus 로고
    • Serotonin acts as a radical scavenger and is oxidized to a dimer during the respiratory burst of human mononuclear and polymorphonuclear phagocytes
    • Schuff-Werner, P., Splettstösser, W., Schmidt, F, and Huether, G. (1995) Serotonin acts as a radical scavenger and is oxidized to a dimer during the respiratory burst of human mononuclear and polymorphonuclear phagocytes. Eur. J. Clin. Invest. 25, 477-484.
    • (1995) Eur. J. Clin. Invest. , vol.25 , pp. 477-484
    • Schuff-Werner, P.1    Splettstösser, W.2    Schmidt, F.3    Huether, G.4
  • 66
    • 1842292742 scopus 로고    scopus 로고
    • Serotonin acts as a radical scavenger and is oxidized to a dimer during the respiratory burst of activated microglia
    • Huether, G., Fettk̈tter, I., Keilhoff, G., and Wolf, G. (1997) Serotonin acts as a radical scavenger and is oxidized to a dimer during the respiratory burst of activated microglia. J. Neurochem. 69, 2096-2101.
    • (1997) J. Neurochem. , vol.69 , pp. 2096-2101
    • Huether, G.1    Fettk̈tter, I.2    Keilhoff, G.3    Wolf, G.4
  • 67
    • 0025949752 scopus 로고
    • Modification of brain guanine nucleotide-binding regulatory proteins by tryptamine-4,5-dione, a neurotoxic derivative of serotonin
    • Fishman, J. B., Jordon, J. B., Chen, J.-C., Dickey, B. F., and Volker, L. (1991) Modification of brain guanine nucleotide-binding regulatory proteins by tryptamine-4,5-dione, a neurotoxic derivative of serotonin. J. Neurochem. 56, 1851-1854.
    • (1991) J. Neurochem. , vol.56 , pp. 1851-1854
    • Fishman, J.B.1    Jordon, J.B.2    Chen, J.-C.3    Dickey, B.F.4    Volker, L.5
  • 69
    • 0027332651 scopus 로고
    • Brain α-ketoglutarate dehydrogenase complex activity in Alzheimer's disease
    • Mastrogiacomo, F., Bergeron, C., and Kish, S. J. (1993) Brain α-ketoglutarate dehydrogenase complex activity in Alzheimer's disease. J. Neurochem. 61, 2007-2014.
    • (1993) J. Neurochem. , vol.61 , pp. 2007-2014
    • Mastrogiacomo, F.1    Bergeron, C.2    Kish, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.