Antinociception induced by stimulating amygdaloid nuclei in rats: Changes produced by systemically administered antagonists

Brazilian Journal of Medical and Biological Research

Volumn 31, Issue 5, 1998, Pages 681-690

  Oliveira, M A ^a   Prado, W A ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Amygdala; Antinociception; Central nucleus of the amygdala; Medial nucleus of the amygdala; Stimulation produced antinociception; Tail flick test

Indexed keywords

ATROPINE; BETA ADRENERGIC RECEPTOR; MECAMYLAMINE; METHYSERGIDE; MUSCARINIC RECEPTOR; NALOXONE; OPIATE RECEPTOR; PHENOXYBENZAMINE; PROPRANOLOL;

ADRENERGIC SYSTEM; AMYGDALOID NUCLEUS; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; AVERSIVE BEHAVIOR; BRAIN DEPTH STIMULATION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; INTRAPERITONEAL DRUG ADMINISTRATION; LATENT PERIOD; MALE; NONHUMAN; RAT; TAIL FLICK TEST;

ANIMALIA;

EID: 0031802863     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X1998000500013     Document Type: Article

References (66)

1. Basbaum AI (1982). Anatomical Substrates for the descending control of nociception. In: Sjölund B & Björklund A (Editors), Brain Stem Control of Spinal Mechanisms. Elsevier, Amsterdam, 119-133.
2. Besson JM & Chaouch A (1987). Peripheral and spinal mechanisms of nociception. Pharmacological Reviews, 67: 67-186.
3. Kuypers HGJM (1982). A new look at the organization of the motor system. In: Kuypers HGJM & Martin GF (Editors), Anatomy of Descending Pathways to the Spinal Cord. Progress in Brain Research. Vol. 57. Elsevier, Amsterdam, 381-403.
4. Zhou ZF, Du MY, Jiang Y & Han JS (1981). Effect of intracerebral microinjection of naloxone on acupuncture and morphine analgesia in the rabbit. Scientia Sinica, 24: 1166-1178.
5. LeDoux JE (1987). Emotion. In: Plum F (Editor), Handbook of Physiology: Nervous System V. American Physiological Society, Washington, DC, 419-459.
6. Good AJ & Westbrook RF (1995). Effects of a microinjection of morphine into the amygdala on the acquisition and expression of conditioned fear and hypoalgesia in rats. Behavioral Neuroscience, 109: 631-641.
7. Helmstetter F (1992). The amygdala is essential for the expression of conditioned hypoalgesia. Behavioral Neuroscience, 106: 518-528.
8. Helmstetter F & Bellgowan PS (1993). Lesions of the amygdala block conditional hypoalgesia in the tail flick test. Brain Research. 612: 253-257.
9. Watkins LR, Wiertelak EP & Maier SF (1993). The amygdala is necessary for the expression of conditioned but not unconditioned analgesia. Behavioral Neuroscience, 107: 402-405.
10. Fox RJ & Sorenson CA (1994). Bilateral lesions of the amygdala attenuate analgesia induced by diverse environmental challenges. Brain Research, 648: 215-221.
11. Manning BH & Mayer DJ (1995). The central nucleus of the amygdala contributes to the production of morphine antinociception in the rat tail-flick test. Journal of Neuroscience, 15: 8199-8213.
12. Manning BH & Mayer DJ (1995). The central nucleus of the amygdala contributes to the production of morphine antinociception in the formalin test. Pain, 63: 141-152.
13. Helmstetter FA, Brozoski EL & Frost JÁ (1991). Kappa opioid agonists produce hypoalgesia in the tail flick test after application to the amygdala. Society for Neuroscience Abstracts, 17: 296.
14. Kalivas PW, Gau BA, Nemeroff CB & Prange AJ (1982). Antinociception after microinjection of neurotensin into the central amygdaloid nucleus of the rat. Brain Research, 243: 279-286.
15. Klamt JG & Prado WA (1991). Antinociception and behavioral changes induced by carbachol microinjected into identified sites of the rat brain. Brain Research, 549: 9-18.
16. Oliveira MA & Prado WA (1994). Antinociception and behavioral manifestations induced by intracerebroventricular or intra-amygdaloid administration of cholinergic agonists in the rat. Pain, 57: 383-391.
17. Rodgers RJ (1977). Elevation of aversive threshold in rats by intra-amygdaloid injection of morphine sulfate. Pharmacology, Biochemistry and Behavior, 6: 385-390.
18. Rodgers RJ (1978). Influence of intra-amygdaloid opiate injections on shock thresholds, tail flick latencies and open field behavior in rats. Brain Research, 153: 211-216.
19. Yaksh TL, Al-Rodhan NRF & Jensen TS (1988). Sites of action of opiates in production of analgesia. In: Fields HL & Besson JM (Editors), Progress in Brain Research. Vol. 77. Elsevier, New York, 371-394.
20. File SE & Rodgers RJ (1979). Partial anxiolytic action of morphine sulphate following microinjection into the central nucleus of the amygdala in rats. Pharmacology, Biochemistry and Behavior, 11: 313-318.
21. Rodgers RJ & File SE (1979). Exploratory behavior and aversive thresholds following intra-amygdaloid application of opiates in rats. Pharmacology, Biochemistry and Behavior, 11: 505-511.
22. Zhou ZF, Xuan YT & Man JS (1984). Analgesic effect of morphine injected into habenula, nucleus accumbens or amygdala of rabbits. Acts Pharmacologica Sinica, 5: 150-153.
23. Davis M (1986). The role of the amygdala in conditioned fear. In: Aggleton JP (Editor), The Amygdala: Neurobiological Aspects of Emotion, Memory, and Mental Dysfunction. Wiley-Liss, New York, 339-351.
24. al-Rodhan N, Chipkin R & Yaksh TL (1990). The antinociceptive effects of SCH-32615, a neutral endopeptidase (enkephalinase) inhibitor, microinjected into the periaqueductal, ventral medulla and amygdala. Brain Research, 520: 123-130.
25. Ma QP, Yin GF, Ai MK & Han JS (1991). Serotonergic projections from the nucleus raphe dorsalis to the amygdala in the rat. Neuroscience Letters, 134: 21-24.
26. Plasnik A, Danysz W & Kostowski W (1985). Some behavioral effects of microinjections of noradrenaline and serotonin into the amygdaloid body of the rat brain. Physiology and Behavior, 34: 481-487.
27. Lico MC, Hoffmann A & Covian MR (1974). Influence of some limbic structures upon somatic and autonomic manifestations of pain. Physiology and Behavior, 12: 805-811.
28. Abbott FV & Melzack R (1978). Analgesia produced by stimulation of limbic structures and its relation to epileptiform after-discharges. Experimental Neurology, 62: 720-734.
29. Sha L, Huang P, Ding W & Teng G (1993). The inhibitory effects of stimulating AC, AL, BNST and AHL on visceral pain. Chen Tzu Yen Chiu Acupuncture Research, 18: 37-43.
30. Mena NB, Mathur R & Nayar U (1995). Amygdalar involvement in pain. Indian Journal of Physiology and Pharmacology, 39: 339-346.
31. Zimmermann M (1983). Ethical guidelines for investigation of pain in conscious animals. Pain, 16: 109-110.
32. König JFR & Klippel RA (1974). The Rat Brain, a Stereotaxic Atlas. Krieger, New York.
33. Litchfield JT & Wilcoxon F (1949). A simplified method of evaluating dose-effect experiments. Journal of Pharmacology and Experimental Therapeutics. 96: 99-113.
34. Azami J, Llewelyn MB & Roberts MHT (1982). The contribution of nucleus reticularis paragigantocellularis and nucleus raphe magnus to the analgesia produced by systemically administered morphine, investigated with the microinjection technique. Pain, 12: 229-246.
35. Applegate CD, Kapp BS, Underwood MD & McNalli CL (1983). Autonomic and somatomotor effects of amygdala central nucleus. Stimulation in awake rabbits. Physiology and Behavior, 31: 353-360.
36. Thorn BE, Applegate L & Jones K (1990). The relative efficacy of monopolar vs. bipolar electrodes in stimulation-produced analgesia. Experimental Brain Research, 79: 266-270.
37. Frenk H & Yitzhaky J (1981). Effects of amygdaloid binding on the pain threshold of the rat. Experimental Neurology, 71: 487-496.
38. Mayer DJ & Hayes RL (1975). Stimulation-produced analgesia: development of tolerance and cross-tolerance to morphine. Science, 188: 941-943.
39. Mansour A, Fox CA, Burke S, Meng F, Thompson RC, Akil H & Watson SJ (1994). Mu, delta, and kappa opioid receptor expression in the rat CNS: an in situ hybridization study. Journal of Comparative Neurology, 350: 412-438.
40. Arvidsson U, Riedl M, Chakrabarti S, Lee JH, Nakano AH, Dado RJ, Loh HH, Law PY, Wessendorff W & Eide R (1995). Distribution and targeting of a μ-opioid receptor (MOR 1) in brain and spinal cord. Journal of Neuroscience, 15: 3328-3341.
41. Gray TS, Cassell MD & Kiss JZ (1984). Distribution of pro-opiomelanocortin derived peptides and enkephalins in the rat central nuclei of the amygdala Brain Research, 306: 354-358.
42. Roberts GW, Woodhams PL, Polak JM & Crow TJ (1982). Distribution of neuropeptides in the limbic system of the rat: the amygdaloid complex. Neuroscience, 7: 99-131.
43. Cassell MD & Gray TS (1989). Morphology of peptide-immunoreactive neurons in the rat central nucleus of the amygdala. Journal of Comparative Neurology, 281: 320-333.
44. Akil H, Mayer DJ & Liebeskind JC (1976). Antagonism of stimulation-produced analgesia by naloxone, a narcotic antagonist. Science, 191: 961-962.
45. Carstens E, Fraunhoffer M & Zimmermann M (1981). Serotonergic mediation of descending inhibition from midbrain periaqueductal gray, but not reticular formation, of spinal nociceptive transmission in the cat. Pain, 10: 149-167.
46. Carstens E, Culhane ES & Banisadr R (1990). Partial involvement of monoamines and opiates in the inhibition of rat spinal nociceptive neurons evoked by stimulation in midbrain periaqueductal gray or lateral reticular formation. Brain Research, 522: 7-13.
47. Fang F & Proudfit HK (1996). Spinal cholinergic and monoamine receptors mediate the antinociceptive effect of morphine microinjected in the penaqueductal gray on the rat tail, but not the feet. Brain Research, 722: 95-108.
48. Guimarāes APC & Prado WA (1994). Antinociceptive effects of carbachol microinjected into different portions of the mesencephalic periaqueductal gray matter of the rat. Brain Research, 647: 220-230.
49. Saxena PR (1995). Serotonin receptors: subtypes, functional responses and therapeutic relevance. Pharmacological Therapeutics, 66: 339-368.
50. Phillips WJ, Enyeart JJ & Hinkle PM (1989). Pituitary thyrotropin-releasing hormone receptors: local anesthetic effects on binding and responses. Molecular Endocrinology, 3: 1345-1351.
51. Mayer DJ & Liebeskind JC (1974). Pain reduction by focal electrical stimulation of the brain: an anatomical and behavioral analysis. Brain Research, 68: 73-93.
52. Mizuno N, Takahashi O, Satoda T & Matsushima R (1985). Amygdalospinal projections in the macaque monkey. Neuroscience Letters, 53: 327-330.
53. Sandrew BB, Edwards DL, Poletti CE & Foote WE (1986). Amygdalospinal projections in the cat. Brain Research, 373: 235-239.
54. Beitz AJ (1982). The organization of afferent projections to the midbrain periaqueductal gray of the rat. Neuroscience, 7: 133-159.
55. Eberhart JÁ, Morrell JI, Krieger MS & Pfaff DW (1985). An autoradiographic study of projections ascending from the midbrain central gray, and from the region lateral to it, in the rat. Journal of Comparative Neurology, 241: 285-310.
56. Rizvi TA, Ennis M, Behbehani MM & Shipley MT (1991). Connections between the central nucleus of the amygdala and the midbrain periaqueductal gray: topography and reciprocity. Journal of Comparative Neurology, 303: 121-131.
57. Li YQ, Takada M, Matsuzaki S, Shinonasa Y & Mizuno N (1993). Identification of periaqueductal gray and dorsal raphe nucleus projecting to both the trigeminal sensory complex and forebrain structures: a fluorescent retrograde double-labeling study in the rat. Brain Research. 623: 267-277.
58. Shaikh MB, Schubert K & Siegel A (1994). Basal amygdaloid facilitation of midbrain periaqueductal gray elicited defensive rage behavior in the cat is mediated through NMDA receptors. Brain Research. 635: 187-195.
59. Cameron AA, Khan IA, Westlund KN, Cliffer KD & Willis WD (1995). The efferent projections of the periaqueductal gray in the rat: a Phaseolus vulgans-leucoagglutinin study. I. Ascending projections. Journal of Comparative Neurology, 351: 568-584.
60. Hopkins DA & Holstege G (1978). Amygdaloid projections to the mesencephalon, pons and medulla oblongata in the cat. Experimental Brain Research, 32: 529-547.
61. Ganteras NS, Simerly RB & Swanson LW (1995). Organization of projections from the medial nucleus of the amygdala: a PHAL study in the rat. Journal of Comparative Neurology, 360: 213-245.
62. Krettek JE & Price JL (1978). Amygdaloid projections to subcortical structures within the basal forebrain and brainstem in the rat and cat. Journal of Comparative Neurology, 178: 225-253.
63. Veening JG, Swanson LW & Sawchenko PE (1984). The organization of projections from the central nucleus of the amygdala to brainstem sites involved in central autonomic regulation: a combined retrograde transport-immunohistochemical study. Brain Research. 303: 337-357.
64. Wallace DM, Magnuson DJ & Gray TS (1989). The amygdalo-brainstem pathway: selective innervation of dopaminergic, noradrenergic and adrenergic cells in the rat. Neuroscience Letters, 97: 252-258.
65. DeSalles AF, Katayama Y, Becher MP & Hayes RL (1985). Pain suppression induced by electrical stimulation of the pontine parabrachial region. Journal of Neurosurgery, 62: 397-407
66. 2-adrenoceptors. Brain Research, 364: 315-330.