Clonality of B-cells in portal lymphoid infiltrates of HCV-infected livers

Journal of Pathology

Volumn 185, Issue 1, 1998, Pages 86-90

  Magalini, Alba Rosa ^a   Facchetti, Fabio ^b   Salvi, Lucia ^b   Fontana, Lucia ^b   Puoti, Massimo ^b   Scarpa, Aldo ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

Author keywords

B lymphocytes; Clonality; Gene rearrangement; HCV; Hepatitis; Polymerase chain reaction

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; VIRUS RNA;

ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CRYOGLOBULINEMIA; GENE REARRANGEMENT; HEPATITIS C; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN GENE; LYMPHOCYTE CLONE; LYMPHOCYTIC INFILTRATION; POLYMERASE CHAIN REACTION; PORTAL VEIN; PRIORITY JOURNAL;

B-LYMPHOCYTES; CELL DIVISION; CLONE CELLS; CRYOGLOBULINEMIA; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; HEPATITIS C, CHRONIC; HUMANS; IMMUNOENZYME TECHNIQUES; LIVER; POLYMERASE CHAIN REACTION;

EID: 0031802716     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199805)185:1<86::AID-PATH59>3.0.CO;2-R     Document Type: Article

References (34)

1. Ferri C, Greco F, Longombardo G, et al. Antibodies to hepatitis C virus in mixed cryoglobulinemia patients. Arthr Rheum 1991; 34: 1606-1610.
2. Agnello V, Chung RT, Kaplan LM. A role for hepatitis C virus infection in type II cryoglobulinemia. N Engl J Med 1992; 327: 1490-1495.
3. Perl A, Gorevic PD, Ryan DH, Condemi JJ, Ruszkowski RJ, Abraham GN. Clonal B cell expansion in patients with essential mixed cryoglobulinemia. Clin Exp Immunol 1989; 76: 54-60.
4. Pozzato G, Mazzaro C, Crovatto M, et al. Low-grade malignant lymphoma, hepatitis C virus infection, and mixed cryoglobulinemia. Blood 1994; 84: 3047-3053.
5. Franzin F, Efremov DG, Pozzato G, Tulissi P, Batista F, Burrone OR. Clonal B-cell expansions in peripheral blood of HCV-infected patients. Br J Haematol 1995; 90: 548-552.
6. Ferri C, Monti M, La Civita L, et al. Hepatitis C virus infection in non-Hodgkin's B-cell lymphoma complicating mixed cryoglobulinemia. Eur J Clin Invest 1994; 24: 781-784.
7. Ferri C, Caracciolo F, Zignego AL, et al. Hepatitis C virus infection in patients with non-Hodgkin's lymphoma. Br J Haematol 1994; 88: 392-394.
8. Luppi M, Ferrari MG, Bonaccorsi G, et al. Hepatitis C virus infection in subsets of neoplastic lymphoproliferations not associated with cryoglobulinemia. Leukemia 1996; 10: 351-355.
9. Luppi M, Longo G, Ferrari MG, et al. Additional neoplasms and HCV infection in low-grade lymphoma of MALT type. Br J Haematol 1996; 94: 373-375.
10. Silvestri F, Pipan C, Barillari G, et al. Prevalence of hepatitis C virus infection in patients with lymphoproliferative disorders. Blood 1996; 87: 4296-4301.
11. Shimizu Y-K, Iwamoto A, Hijkata M, Purcell RH, Yashikura H. Evidence for in vitro replication of hepatitis C virus genome in a human T-cell line. Proc Natl Acad Sci USA 1992; 89: 5477-5481.
12. Muller HM, Pfaff E, Goeser T, Kallinowski B, Solbach C, Theilmann L. Peripheral blood leukocytes serve as possible extrahepatic sites for hepatitis C replication. J Gen Virol 1993; 74: 669-676.
13. Zignego AL, De Carli M, Monti M, et al. Hepatitis C virus infection of mononuclear cells from peripheral blood and liver infiltrates in chronically infected patients. J Med Virol 1995; 47: 58-64.
14. Ferri C, Monti M, La Civita L, et al. Infection of peripheral blood mononuclear cells by hepatitis C virus in mixed cryoglobulinemia. Blood 1993; 82: 3701-3709.
15. Muratori L, Gibellini D, Lenzi M, et al. Quantification of hepatitis C virus-infected peripheral blood mononuclear cells by in situ reverse transcriptase-polymerase chain reaction. Blood 1996; 88: 1768-1774.
16. Scheuer P, Ashrafzadeh P, Sherlock S, Brown D, Dusheiko GM. The pathology of hepatitis C. Hepatology 1992; 15: 567-571.
17. Hino K, Okuda M, Kinoshi T, et al. Analysis of lymphoid follicles in liver of patients with chronic hepatitis C. Liver 1992; 12: 387-391.
18. Mosnier JF, Defott C, Marcellin P, Henin D, Erlingr S, Benhamou JP. The intraportal lymphoid nodule and its environment in chronic active hepatitis C: an immunohistochemical study. Hepatology 1993; 17: 366-371.
19. Achille A, Scarpa A, Montresor M, et al. Routine application of polymerase chain reaction in the diagnosis of monoclonality of B-cell lymphoid proliferations. Diagn Mol Pathol 1995; 4: 14-24.
20. Scarpa A, Capelli P, Zamboni G, et al. Neoplasia of the ampulla of Vater: Ki-ras and p53 mutations. Am J Pathol 1993; 142: 1163-1172.
21. Liu Y-J, Banchereau J. The paths and molecular controls of peripheral B-cell development. Immunologist 1996; 4: 55-66.
22. Pan LX, Diss TC, Peng HZ, Isaacson PG. Clonality analysis of defined B-cell populations in archival tissue sections using microdissection and the polymerase chain reaction. Histopathology 1994; 24: 323-327.
23. Fishleder A, Tubbs R, Hesse B, Levine H. Uniform detection of immunoglobulin-gene rearrangement in benign lymphoepithelial lesions. N Engl J Med 1987; 316: 1118-1121.
24. Knowles DM, Athan E, Ubriaco A, et al. Extranodal noncutaneous lymphoid hyperplasias represent a continuous spectrum of B-cell neoplasia: demonstration by molecular genetic analysis. Blood 1989; 73: 1635-1645.
25. Negro F, Pacchioni D, Shimizu Y, et al. Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridizaton and comparison with histopathology. Proc Natl Acad Sci USA 1992; 89: 2247-2251.
26. Koheler H, Goudsmit J, Nara P. Clonal dominance: cause for a limited and failing immune response to HIV-1 infection and vaccination. J AIDS 1992; 5: 1158-1168.
27. Amadori A, Gallo P, Zamarchi R, et al. IgG oligoclonal bands in sera of HIV-1 infected patients are mainly directed against HIV-1 determinants. AIDS Res Hum Retroviruses 1990; 6: 581-586.
28. Houghton M, Weiner A, Han J, Kuo G, Choo Q-L. Molecular biology of the hepatitis C viruses: implications for diagnosis, development and control of viral disease. Hepatology 1991; 14: 381-388.
29. Sakamuro D, Furukawa T, Takegami T. Hepatitis C virus nonstructural protein NS3 transforms NIH 3T3 cells. J Virol 1995; 69: 3893-3896.
30. Suzuki R, Matsuura Y, Suzuki T, Miyamura T. Nuclear localization of the truncated hepatitis C virus core protein with its hydrophobic C-terminus deleted. J Gen Virol 1995; 9: 271-296.
31. Hsi ED, Greenson JK, Singleton TP, Siddiqui J, Schnitzer B, Ross CW. Detection of immunoglobulin heavy chain gene rearrangement by polymerase chain reaction in chronic active gastritis associated with Helicobacter pylori. Hum Pathol 1996; 27: 290-296.
32. Knowles DM, Cesarman E, Chadburn A, et al. Correlative morphologic and molecular genetic analysis demonstrates three distinct categories of posttransplantation lymphoproliferative disorders. Blood 1995; 85: 552-565.
33. Isaacson PG. Recent developments in our understanding of gastric lymphomas. Am J Surg Pathol 1996; 20: S1-S7.
34. Ellis M, Rathaus M, Amiel A, et al. Monoclonal lymphocyte proliferation and bcl-2 rearrangement in essential mixed cryoglobulinemia. Eur J Clin Invest 1995; 25: 833-837.