Mutations in adrenocortical tumors

Hormone and Metabolic Research

Volumn 30, Issue 6-7, 1998, Pages 447-455

  Reincke, M ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Adrenocortical Adenoma; Adrenocortical Carcinoma; Oncogene; Steroidogenesis; Tumor Suppressor Gene; Tumorigenesis

Indexed keywords

CORTICOTROPIN RECEPTOR; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN P53;

ADRENAL CORTEX TUMOR; ARTICLE; BECKWITH WIEDEMANN SYNDROME; CANCER INCIDENCE; CHROMOSOME 11P; FAMILIAL CANCER; GENE DELETION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERALDOSTERONISM; MULTIPLE ENDOCRINE NEOPLASIA; PREVALENCE; PRIORITY JOURNAL; SYNDROME DELINEATION; TUMOR SUPPRESSOR GENE;

EID: 0031802542     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-978913     Document Type: Article

References (69)

1. Kloos RT, Gross MD, Francis IR, Korobkin M, Shapiro B. Incidentally discovered adrenal masses. Endocr Rev 1995; 16: 160-83
2. Latronico AC, Chrousos GP. Extensive personal experience: Adrenocortical tumors. J Clin Endocrinol Metab 1997; 82: 1317-24
3. Reincke M, Allolio B. Das Nebenniereninzidentalom: Die Kunst der Beschränkung in Diagnostik und Therapie. Dtsch Ärzteblatt [A] 1995; 92: 764-70
4. Lipsett MB, Hertz R, Ross GT. Clinical and pathophysiologic aspects of adrenocortical carcinoma. Am J Med 1963; 35: 374
5. Søreide JA, Braband K, Thoresen SØ. Adrenal cortical carcinoma in Norway, 1970-1984. World J Surg 1992; 16: 663-8
6. Li FP, Frauemeni JF. Soft-tissue sarcomas, breast cancer, and other neoplasms: A familial syndrome? Ann Int Med 1969; 71: 747-52
7. Malkin D, Jolly KW, Barbier N, Look AT, Friend SH, Cebhardt MC, Anderson TI, Boerrson A-L, Li FP, Garber J, Strong LC. Germline mutations of the p53 tumor suppressor gene in children and young adults with second malignant neoplasms. N Engl J Med 1992; 326: 1309-15
8. Srivastava S, Zou Z, Pirollo K, Blattner W, Chang EH. Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature 1990; 348: 747-9
9. Malkin D, Li FP, Strong LC, et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 1990; 250: 1233-8
10. Hollstein M, Sidransky D, Vogelstein B, Harris CC. p53 mutations in human cancers. Science 1991; 253: 49-54
11. Grayson GH, Moore S, Schneider BG, Saldivar V, Hensel CH. Novel germline mutation of the p53 tumor suppressor gene in a child with incidentally discovered adrenal cortical carcinoma. Am J Pediatr Hematol Oncol 1994; 16: 341-7
12. Wagner J, Portwine C, Rabin K, Leclerc JM, Narod SA, Malkin D. High frequency of germline p53 mutations in childhood adrenocortical cancer. J Natl Cancer Inst 1994; 86: 1707-10
13. Wiedemann HR. Complex malformatif familial avec hernie ombilicale et macroglossie - un syndrome nouveau? J Genet Hum 1964; 13: 223-32
14. Beekwith JB. Macroglossia, omphalocoele, adrenal cytomegaly, gigantism and hyperplastic visceromegalie. Birth Defects 1969; 5: 188-96
15. Koufos A, Grundy P, Morgan K, Aleck KA, Hadreos T, Lampkin BC, Kalbakji A, Cavenee WK. Familial Wiedemann-Beckwith syndrome and a second Wilms tumor locus both map to 11 p15.5. Am J Genet 1989; 44: 711-9
16. Henry I, Bonaiti-Pellie C, Chehensse V, Beldjord C, Schwartz C, Utermann G, Junien C. Uniparental paternal disomy in a genetic cancer-predisposing syndrome. Nature 1991; 351: 667-70
17. Gicquel C, Xavier B, Schneid H, Francillard-Leblond M, Luton J-P, Girard F, Le Bouc Y. Rearrangement at the 11 p15 locus and overexpression of IGF-II gene in sporadic adrenocortical tumors. J Clin Endocrinol Metab 1994; 78: 1444-53
18. Chandrasekharrapa SC, Guru SC, Manickam P, Olufemi SE, et al. Positional cloning of the gene for multiple endocrine neoplasia type 1. Science 1997; 276: 404-7
19. Larson C, Scogseid B, Öberg K, Nakamura Y, Nordenskjöld M. MEN type 1 gene maps to chromosome 11 and is lost in insulinoma. Nature 1988; 332: 85-7
20. Skogseid B, Larsson C, Lindgren P-G, Kvanta E, Rastad J, Theodorsson E, Wide L, Wilander E, Öberg K. Clinical and genetic features of adrenocortical lesions in MEN type 1. J Clin Endocrinol Metab 1992; 75: 76-81
21. Sutherland DJ, Ruse JL, Laidlaw JC. Hypertension, increased aldosterone secretion and low plasma renin activity relieved by dexamethasone. Canad Med Assoc J 1966; 95: 1109-19
22. Lifton RP, Dluhy RG, Powers M, Rich GM, Cook S, Ulick S, Lalouel JM. A chimeric 11β-hydroxylase/aldosterone synthase gene causes glucocorticoid-remidiable aldosteronism and human hypertension. Nature 1992; 355: 262-5
23. Pascoe L, Jeunemaitre X, Lebrethon MC, Cumow KM, Gomez-Sanchez CE, Gasc JM, Saez JM, Corvol P. Glucocorticoid-suppressible hyperaldosteronism and adrenal tumors occuring in a single French pedigree. J Clin Invest 1995; 96: 2236-46
24. Stowasser M, Gordon RD, Tunny TJ, Klemm SA, Finn WL, Krek AL. Familial hyperaldosteronism type II: Five families with a new variety of primary aldosteronism. Clin Experim Pharmacol Physiol 1992; 19: 319-22
25. Stratakis CA, Carney JA, Lin J-P, et al. Carney complex: A familial multiple neoplasia and lentiginosis syndrome: Analysis of 11 kindred and linkage to the short arm of chromosome 2. J Clin Invest 1996; 97: 599-607
26. Schteingart DE, Tsao HS. Coexistence of pituitary ACTH-dependent Cushing's syndrome with a solitary adrenal adenoma. J Clin Endocrinol Metab 1980; 50: 961-6
27. Hermus AR, Pieters GF, Smals AG, Pesman GJ, Lamberts SW, Benraad TJ, van Haelst UJ, Kloppenborg PW. Transition from pituitary-dependent to adrenal-dependent Cushing's syndrome. New Engl J Med 1988; 318: 966-70
28. Jaresch S, Schlaghecke R, Jungblut R, Krüskemper HL, Kley HK. Stumme Nebennierentumoren bei Patienten mit adrenogenitalem Syndrom. Klin Wochenschr 1987; 65: 627-33
29. Jaresch S, Kornley E, Kley HK, Schlaghecke R. Adrenal incidentaloma and patients with homozygous and heterozygous congenital adrenal hyperplasia. J Clin Endocrinol Metab 1992; 74: 658-69
30. Reincke M, Allolio B. Molekularbiologie der zufällig diagnostizierten Nebennierenraumforderung. Zentralbl Chir 1997; 122: 430-7
31. Schulze E, Maser-Gluth C, Allolio B, Bornstein S, Reineke M. Steroid hormone levels and 21-hydroxylase mutations in patients with adrenal incidentalomas. 79th Annual Meeting of the Endocrine Society, Minneapolis, USA. Program and Abstracts, 1997; P2-87, 306
32. Fialkow PJ. Clonal origin of human tumors. Biochim Biophys Acta 1976; 458: 283-321
33. Knudson AG. Mutation and human cancer. Adv Cancer Res 1993; 17: 317-52
34. Gicquel C, Leblond-Francillard M, Bertagna X, Louvel A, Chapuls Y, Luton J-P, Girard F, Le Bouc Y. Clonal analysis of human adrenocortical carcinomas and secreting adenomas. Clin Endocrinol 1994; 40: 465-77
35. Beuschlein F, Reineke M, Karl M, Travis W, Jaursch-Hancke C, Abdelhamid S, Chrousos GP, Allolio B. Clonal composition of human adrenocortical neoplasms. Cancer Res 1994; 54: 4927-32
36. Rico AF, Shao XJ, Gawlitza M, Hensen J. Analysis of clonality in frozen and paraffin-embeded adrenocortical neoplasms by PCR-amplification of short tandem repeats of the human androgen receptor gene. Exp Clin Endocrinol Diab 1997; 105 (Suppl. 1): 14-5
37. Gicquel C, Bertagna B, Le Bouc Y. Recent advances in the pathogenesis of adrenocortical tumors. Eur J Endocrinol 1995; 133: 133-44
38. Yano T, Linehan M, Anglard P, Lerman MI, Daniel LN, Stein CA, Robertson N, LaRocca R, Zbar B. Genetic changes in human adrenocortical carcinoma. J Natl Cancer Inst 1989; 81: 518-23
39. Limon J, Dal Cin P, Gaeat J, Sandberg A. Translocation t(4;11) (q35; p13) in an adrenocortical carcinoma. Cancer Genet Cytogenet 1987; 28: 343-8
40. Herrmann M, Rydstedt L, Talpos G, Ratner S, Wollman S, Lalley P. Chromosomal aberrations in two adrenocortical tumors, one with rearrangement at 11 p15. Cancer Genet Cytogenet 1994; 75: 111-6
41. Gordon RD, Stowasser M, Martin N, Epping A, Conic S, Klemm SA, Tunny TJ, Rutherford JC. Karyotypic abnormalities in benign adrenocortical tumors producing aldosterone. Cancer Genet Cytogenet 1993; 68: 78-81
42. Rosenberg C, Della-Rosa VA, Latronico AC, Mendoca BB, Vianna-Morgante AM. Selection of adrenal tumor cells in culture demonstrated by interphase cytogenetics. Cancer Genet Cytogenet 1994; 79: 36-40
43. Kjellman M, Kallioniemi OP, Karhu R, Höög A, Farnebo LO, Auer G, Larsson C, Bäckdahl M. Genetic abberations in adrenocortical tumors detected using comparative genomic hybridization correlate with tumor size and malignancy. Cancer Res 1996; 56: 4219-23
44. Reincke M, Dohna M, Solinas-Toldo S, Allolio B, Lichter P. Multiple chromosomal aberrations in benign and malignant adrenocortical tumors using comparative genomic hybridization, 79th Annual Meeting of The Endocrine Society, Minneapolis, USA. Program and Abstracts, 1997; P2-108, 311
45. Lyons J, Landis CA, Harsh G, Vallar L, Grünewald K, Feichtinger H, Duh QY, Clark OH, Kawasaki E, Bourne HR, McCormick F. Two G protein oncogenes in human endocrine tumors. Science 1990; 249: 655-9
46. Parma J, Duprez L, Van Sande J, Cochaux P, Gervy C, Mockel J, Dumont J, Vasart G. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature 1993; 365: 649-51
47. Estivariz FE, Iturriza F, Mclean C, Hope J, Lowry PJ. Stimulation of adrenal mitogenesis by N-terminal proopiomelanocortin. Nature 1982; 297: 419-22
48. Latronico AC, Reincke M, Mendonca BB, et al. No evidence for oncogenic mutations in the adrenocorticotropin receptor gene in human adrenocortical neoplasms. J Clin Endocrinol Metab 1995; 80: 875-7
49. Light K, Jenkins PJ, Weber A, Perrett C, Grossman A, Pistorello M. Asa SL, Clayton RN, Clark AJL. Are activating mutations of the ACTH receptor involved in adrenal cortical neoplasia? Life Sci 1995; 56: 1523-7
50. Reincke M, Karl M, Travis W, Chrousos GP. No evidence for oncogenic mutations in guanine nucleotide binding proteins of human adrenocortical neoplasms. J Clin Endocrinol Metab 1993; 77: 1419-22
51. Gicquel C, Dib A, Bertagna X, Amselem S, Le Bouc Y. Oncogenic mutations of alpha-Gi2 are not determinant for human adrenocortical tumorigenesis. Eur J Endocrinol 1995; 133: 166-72
52. Reincke M, Mora P, Beuschlein F, Arlt W, Chrousos GP, Allolio B. Deletion of the ACTH receptor gene in adrenocortical tumors: Implication for tumorigenesis. J Clin Endocrinol Metab 1997; 82: 3054-8
53. Sachse R, Shao X-J, Rico A, Finckh U, Rolfs A, Reincke M, Hensen J. Absence of angiotensin II type 1 receptor gene mutations in human adrenal tumors. Eur J Endocrinol, submitted
54. Latronieo AC, Mendonca BB, Bianco AC, Villares SM, Lucon MA, Nicolau W, Wajchenberg BL. Calcium-dependent protein kinase-C activity in human adrenocortical neoplasms, hyperplastic adrenals, and normal adrenal tissue. J Clin Endocrinol Metab 1994; 79: 736-9
55. Moul JW, Bishoff JT, Theune SM, Chang EH. Absent ras gene mutations in human adrenal cortical neoplasms and pheochromocytomas. J Urology 1993; 149: 1389-94
56. Ohgaki H, Kleihues P, Heitz PU. p53 mutations in sporadic adrenocortical tumors. Int J Cancer 1993; 54: 408-10
57. Yashiro T, Hara H, Obara T, Kaplan EL. Point mutation of ras in human adrenal cortical tumor: Absence in adrenocortical hyperplasia. World J Surg 1994; 18: 455-60
58. Gicquel C, Raffin-Sanson ML, Gaston V, Bertagna X, Plouin PF, Schlumberger M, Louvel A, Luton JP, Le Bouc Y. Structural and functional abnormalities at 11 p15 are associated with the malignant phenotype in sporadic adrenocortical tumors: Study on a series of 82 tumors. J Clin Endocrinol Metab 1997; 82: 2559-65
59. Ilvesmäki V, Kahri AI, Miettinen PJ, Voutilainen R. Insulin-like growth factors and their receptors in adrenal tumors: High IGF II expression in functional adrenocortical carcinomas. J Clin Endocrinol Metab 1993; 77: 852
60. Lin SR, Lee YJ, Tsai JH. Mutations of the p53 gene in human functional neoplasms. J Clin Endocrinol Metab 1994; 78: 483-91
61. Reincke M, Wachenfeld C, Mora P, Thumser A, Jaursch-Hancke C, Abdelhamid S, Chrousos GP, Allolio B. p53 mutations in adrenal tumors: Caucasian patients do not show the exon 4 "hot spot" found in Taiwan. J Clin Endocrinol Metab 1996; 81: 3636-8
62. Reincke M, Karl M, Travis WH, Mastorakos G, Allolio B, Linehan HM, Chrousos GP. p53 mutations in human adrenocortical neoplasms: Immunohistochemical and molecular studies. J Clin Endocrinol Metab 1994; 78: 790-4
63. KIP2, IGF-II, and H19, in adrenal tumors and cultered adrenal cells. J Clin Endocrinol Metab 1997; 82: 1766-71
64. Kamio T, Shigematsu K, Kawai K, Tsuchiyama H. Immunoreactivity and receptor expression of IGF-I and insulin in human adrenal tumors. Am J Pathol 1991; 138: 83-91
65. Levine AJ, Momand J, Finlay CA. The p53 tumour suppressor gene. Nature 1991; 351: 453-6
66. Esrig D, Elmajian D, Cote RJ. Accumulation of nuclear p53 and tumor progression in bladder cancer. N Engl J Med 1994; 331: 1259-64
67. Baker SJ, Preisinger AC, Jessup JM, Paraskeva C, Markowitz S, Willson JKV, Hamilton S, Vogelstein B. p53 gene mutations occur in combination with 17 p allelic deletions as late events in colorectal tumorigenesis. Cancer Res. 1990; 50: 7717-22
68. Caron de Fromentel C, Soussi T. p53 tumor suppressor gene: A model for investigating human mutagenesis. Genes Chrom Cancer 1992; 4: 1-15
69. Hartmann A, Blaszyk H, Sommer SS. p53 gene mutations inside and outside of exons 5-8: The patterns differ in breast and other cancers. Oncogene 1995; 10: 681-8