Arrest of the cell cycle reduces susceptibility of target cells to perforin-mediated lysis

Journal of Cellular Biochemistry

Volumn 69, Issue 4, 1998, Pages 425-435

  De Leon, Marisela ^a   Jackson, Kimberly M ^a   Cavanaugh, Jay R ^b   Mbangkollo, David ^a   Verret, C Reynold ^a  

^a CLARK ATLANTA UNIVERSITY   (United States)

^b Tulane University   (United States)

Author keywords

Apoptosis; Cell cycle; DNA synthesis; Perforin; T lymphocyte

Indexed keywords

APHIDICOLIN; CYTOLYSIN; DNA; FAS ANTIGEN; MONOCLONAL ANTIBODY; PERFORIN; THYMIDINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; B CELL LYMPHOMA; CELL CYCLE PHASE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; DNA SYNTHESIS INHIBITION; FLOW CYTOMETRY; MASTOCYTOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; TARGET CELL;

ANIMALS; ANTIGENS, CD95; APHIDICOLIN; APOPTOSIS; CELL CYCLE; CELL DEATH; CELL LINE; CYTOPLASMIC GRANULES; CYTOTOXICITY, IMMUNOLOGIC; LYMPHOMA, B-CELL; MAST-CELL SARCOMA; MEMBRANE GLYCOPROTEINS; MICE; PORE FORMING CYTOTOXIC PROTEINS; T-LYMPHOCYTES, CYTOTOXIC; THYMIDINE; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0031801263     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19980615)69:4<425::AID-JCB4>3.0.CO;2-P     Document Type: Article

References (25)

1. Allbritton NL, Verret CR, Wolley RC, Eisen HN (1988): Calcium ion concentrations and DNA fragmentation in target cell destruction by murine cloned cytotoxic T lymphocytes. J Exp Med 167: 514-527.
2. +2. J Immunol 137:263-270.
3. Coligan JR, Kruisbeek AM, Magulle DM, Shevach EM, Strober W (eds) (1991): "Current Protocols in Immunology." New York: John Wiley & Sons.
4. Fox RM, Tripp EH, Tattersall MNH (1980): Mechanism of deoxycytidine rescue of thymidine toxicity in human T-leukemic lymphocytes. Cancer Res 40:1715-1721.
5. Henkart PA, Millard PJ, Reynolds CW, Henkart MP (1984): Cytolytic activity of purified cytoplasmic granules. J Exp Med 160:75-93.
6. Henkart PA, Hayes MP, Shriver JW (1993): The granule exocitosis model for lymphocyte cytotoxicity and its relevance to target cell DNA breakdown. In Sitkovsky MV, Henkart PA (eds): "Cytotoxic Cells." Cambridge, MA: Birkhauser Boston, pp 153-185.
7. Jiang S, Persechini PM, Zychlinsky A, Liu CC, Perussia B, Young JD (1988): Resistance of cytolytic lymphocytes to perforin-mediated killing. J Exp Med 168:2207-2219.
8. Jones J, Morgan P (1991): Killing of cells by perforin. Biochem J 280:199-204.
9. Jones J, Hallet HB, Morgan RP (1990): Reversible cell damage by T-cell perforin. Biochem J 267:303-307.
10. Kagi D, Ledermann B, Burki K, Seiler P, Odermatt B, Olsen KJ, Podack ER, Zinkernagel RM, Hengartner H (1994a): Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 369:31-37.
11. Kagi D, Vignnaux F, Ledermann L, Burki K, Depraetere V, Nagata S, Hengartner H, Golstein P (1994b): Fas and perforin pathways as major mechanism of T cell-mediated cytotoxicity. Science 265:528-530.
12. Komada Y, Zhou YW, Xue ML, Sakai M, Tanaka S, Sakatoku H, Sakuri M (1995): Fas-receptor-(Cd95) - mediated apoptosis is induced in leukemic cells entering G1b compartment of the cell cycle. Blood 86:3848-3860.
13. Lowin B, Hahne M, Mattmann C, Tschopp J (1994): Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature 37:650-652.
14. Masson DM, Nabholz M, Estrade C, Tschopp J (1986): Granules of cytolytic T lymphocytes contain two serine esterases. EMBO J 5:1595-1600.
15. Meinkrantz W, Schlegel R (1995): Apoptosis and cell-cycle. J Cell Biochem 58:160-174.
16. Muller C, Tschopp J (1994): Resistance of CTL to perforin-mediatedlysis. J Immunol 153:2471-2478.
17. Nishioka WK, Welsh RM (1994): Susceptibility to cytotoxic T lymphocytes induced apoptosis is function of the proliferative status of the target. J Exp Med 179:769-774.
18. Ojcius DM, Jiang SB, Persechini PM, Detmers PA, Young JD (1991): Cytoplasts from cytotoxic T lymphocytes are resistant to perforin-mediated lysis. Mol Immunol 28: 1011-1018.
19. Pasternack MS, Verret RC, Liu MA, Eisen HN (1986): Serine esterase in cytolytic T lymphocytes. Nature 322: 740-743.
20. Podack R (1986): Molecular mechanism of cytolysis by complement and by cytolytic lymphocytes. J Cell Biochem 30:133-170.
21. Ramm LE, Whitlow MB, Koski CL, Shin ML, Mayer MM (1983): Elimination of complement channels from plasma membranes of U937, a nucleated mammalian cell line: Temperature dependence of the elimination rate. J Immunol 131:1411-1415.
22. Ross D, Joekis CC, Ordonez JV, Sisk AM, Wu RK, Hamburger AW, Nora RE (1989): Estimation of cell survival by flow cytometric quantification of fluorecein diacetate/ propidium iodide viable cell number. Cancer Res 49:3776-3782.
23. Sheaff R, Ilsley D, Kutcha R (1991): Mechanism of DNA polymerase α inhibition by aphidicolin. Biochemistry 30: 8590-8597.
24. Shinkay Y, Ishikawa H, Hahosi M, Okumura K (1988): Resistance of mouse cytolytic cells to pore-forming protein-mediated cytolysis. Eur J Immunol 18:29-33.
25. Verret CR, Firmenich AA, Kranz DM, Eisen HN (1987): Resistance of cytotoxic T lymphocytes to the lytic effects of their toxic granules. J Exp Med 166:1536-1547.