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Volumn 32, Issue 1, 1998, Pages 146-155

CNI-1493 prolongs survival and reduces myocyte loss, apoptosis, and inflammation during rat cardiac allograft rejection

Author keywords

Allograft; CNI 1493; Macrophage; Rejection

Indexed keywords

AMINOGUANIDINE; CYTOKINE; MESSENGER RNA; NITRIC OXIDE SYNTHASE; SEMAPIMOD; UNCLASSIFIED DRUG;

EID: 0031800038     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199807000-00023     Document Type: Article
Times cited : (18)

References (37)
  • 1
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992;6:3051-64.
    • (1992) FASEB J , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 2
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • Moncada S, Palmer RMJ, Higgs A. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991;43:109-42.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, A.3
  • 3
    • 0025881584 scopus 로고
    • Cells mediating allograft rejection
    • Hall BM. Cells mediating allograft rejection. Transplantation 1991;51:1141-51.
    • (1991) Transplantation , vol.51 , pp. 1141-1151
    • Hall, B.M.1
  • 4
    • 0026733084 scopus 로고
    • Cytokine gene expression in rejecting cardiac allografts
    • Wu C, Lovett M, Wong-hee J, et al. Cytokine gene expression in rejecting cardiac allografts. Transplantation 1992;54:326-32.
    • (1992) Transplantation , vol.54 , pp. 326-332
    • Wu, C.1    Lovett, M.2    Wong-hee, J.3
  • 5
    • 0028083226 scopus 로고
    • Induction of myocardial nitric oxide synthase by cardiac allograft rejection
    • Yang X, Chowdhury N, Cai B, et al. Induction of myocardial nitric oxide synthase by cardiac allograft rejection. J Clin Invest 1994;94: 714-21.
    • (1994) J Clin Invest , vol.94 , pp. 714-721
    • Yang, X.1    Chowdhury, N.2    Cai, B.3
  • 6
    • 0028855583 scopus 로고
    • The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor β
    • Pinsky DJ, Cai B, Yang X, Rodriguez C, Sciacca RR, Cannon PJ. The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor β. J Clin Invest 1995;95:677-85.
    • (1995) J Clin Invest , vol.95 , pp. 677-685
    • Pinsky, D.J.1    Cai, B.2    Yang, X.3    Rodriguez, C.4    Sciacca, R.R.5    Cannon, P.J.6
  • 7
    • 0029778443 scopus 로고    scopus 로고
    • Apoptosis of cardiac myocytes during cardiac allograft rejection: Relation to induction of nitric oxide synthase
    • Szabolcs M, Michler RE, Yang X, et al. Apoptosis of cardiac myocytes during cardiac allograft rejection: relation to induction of nitric oxide synthase. Circulation 1996;94:1665-73.
    • (1996) Circulation , vol.94 , pp. 1665-1673
    • Szabolcs, M.1    Michler, R.E.2    Yang, X.3
  • 8
    • 0029258451 scopus 로고
    • An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammatory andendotoxin lethality
    • Bianchi M, Ulrich P, Bloom O, et al. An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammatory andendotoxin lethality. Mol Med 1995;1(3):254-66.
    • (1995) Mol Med , vol.1 , Issue.3 , pp. 254-266
    • Bianchi, M.1    Ulrich, P.2    Bloom, O.3
  • 9
    • 15844399881 scopus 로고    scopus 로고
    • Suppression of proinflammatory cytokines in monocytes by a tetravalent guanylhydrazone
    • Bianchi M, Bloom O, Raabe T, et al. Suppression of proinflammatory cytokines in monocytes by a tetravalent guanylhydrazone. J Exp Med 1996;83:927-36.
    • (1996) J Exp Med , vol.83 , pp. 927-936
    • Bianchi, M.1    Bloom, O.2    Raabe, T.3
  • 10
    • 0025187576 scopus 로고
    • Interferon-gamma overcomes glucocorticoid suppression of cachectin/tumor necrosis factor biosynthesis by murine macrophages
    • Leudke CE, Cerami A. Interferon-gamma overcomes glucocorticoid suppression of cachectin/tumor necrosis factor biosynthesis by murine macrophages. J Clin Invest 1990;86:1234-40.
    • (1990) J Clin Invest , vol.86 , pp. 1234-1240
    • Leudke, C.E.1    Cerami, A.2
  • 11
    • 0014468579 scopus 로고
    • Improved technique of heart transplantation in rats
    • Ono K, Lindsay ES. Improved technique of heart transplantation in rats. J Thorac Cardiovasc Surg 1969;7:225-9.
    • (1969) J Thorac Cardiovasc Surg , vol.7 , pp. 225-229
    • Ono, K.1    Lindsay, E.S.2
  • 12
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of DNA fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of DNA fragmentation. J Cell Biol 1992;119:493-501.
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 14
    • 0030012624 scopus 로고    scopus 로고
    • Low rates of apo e secretion from Hep G 2 cells result from reduced delivery of newly synthesized triglyceride to a "secretion-coupled" pool
    • Wu X, Shang A, Jiang H, Ginsberg HN. Low rates of apo E secretion from Hep G 2 cells result from reduced delivery of newly synthesized triglyceride to a "secretion-coupled" pool. J Lipid Res 1996;37:1198-205.
    • (1996) J Lipid Res , vol.37 , pp. 1198-1205
    • Wu, X.1    Shang, A.2    Jiang, H.3    Ginsberg, H.N.4
  • 15
    • 0025932984 scopus 로고
    • Apoptosis mechanisms and roles in pathology
    • Arends MJ, Wyllie AH. Apoptosis mechanisms and roles in pathology. Int Res Exp Pathol 1991;32:223-54.
    • (1991) Int Res Exp Pathol , vol.32 , pp. 223-254
    • Arends, M.J.1    Wyllie, A.H.2
  • 16
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller H. Mechanisms and genes of cellular suicide. Science 1995;267:1445-9.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 18
    • 0029873504 scopus 로고    scopus 로고
    • Induction of apoptosis in myocardial infarction and its possible relationship to nitric oxide synthase in macrophages
    • Suzuki H, Wildhirl SM, Dudek RR, Narayan KS, Bailey GH, Bing RJ. Induction of apoptosis in myocardial infarction and its possible relationship to nitric oxide synthase in macrophages. Tissue Cell 1996;28(1):89-97.
    • (1996) Tissue Cell , vol.28 , Issue.1 , pp. 89-97
    • Suzuki, H.1    Wildhirl, S.M.2    Dudek, R.R.3    Narayan, K.S.4    Bailey, G.H.5    Bing, R.J.6
  • 19
    • 0030031983 scopus 로고    scopus 로고
    • Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats
    • Kajstura J, Cheng W, Reiss K, et al. Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Lab Invest 1996;74:86-107.
    • (1996) Lab Invest , vol.74 , pp. 86-107
    • Kajstura, J.1    Cheng, W.2    Reiss, K.3
  • 20
    • 0027967047 scopus 로고
    • Hypothesis: Apoptosis may be a mechanism for the transition to heart failure with chronic pressure overload
    • Bing OH. Hypothesis: apoptosis may be a mechanism for the transition to heart failure with chronic pressure overload. J Mol Cell Cardiol 1994;26:943-8.
    • (1994) J Mol Cell Cardiol , vol.26 , pp. 943-948
    • Bing, O.H.1
  • 21
    • 0028334555 scopus 로고
    • Normal and abnormal consequences of apoptosis in the human heart: From postnatal morphogenesis to paroxysmal arrhythmias
    • James TN. Normal and abnormal consequences of apoptosis in the human heart: from postnatal morphogenesis to paroxysmal arrhythmias. Circulation 1994;90:556-73.
    • (1994) Circulation , vol.90 , pp. 556-573
    • James, T.N.1
  • 23
    • 10244254975 scopus 로고    scopus 로고
    • Apoptosis in myocytes in endstage heart failure
    • Narula J, Haider N, Virmani R, et al. Apoptosis in myocytes in endstage heart failure. N Engl J Med 1996;335:1182-9.
    • (1996) N Engl J Med , vol.335 , pp. 1182-1189
    • Narula, J.1    Haider, N.2    Virmani, R.3
  • 24
    • 0030766192 scopus 로고    scopus 로고
    • Apoptosis in the failing human heart
    • Olivetti G, Abbi R, Quaini F, et al. Apoptosis in the failing human heart. N Engl J Med 1997;336:1131-41.
    • (1997) N Engl J Med , vol.336 , pp. 1131-1141
    • Olivetti, G.1    Abbi, R.2    Quaini, F.3
  • 25
    • 0028786990 scopus 로고
    • Stretch-induced programmed myocyte cell death
    • Cheng W, Li B, Kajstura J, et al. Stretch-induced programmed myocyte cell death. J Clin Invest 1995;96:2247-59.
    • (1995) J Clin Invest , vol.96 , pp. 2247-2259
    • Cheng, W.1    Li, B.2    Kajstura, J.3
  • 26
    • 0027231742 scopus 로고
    • Nitric oxide mediated apoptosis in murine peritoneal macrophages
    • Albina JE, Cui S, Mateo RB, Reichner JS. Nitric oxide mediated apoptosis in murine peritoneal macrophages. J Immunol 1993;150: 5080-5.
    • (1993) J Immunol , vol.150 , pp. 5080-5085
    • Albina, J.E.1    Cui, S.2    Mateo, R.B.3    Reichner, J.S.4
  • 28
  • 29
    • 0029932157 scopus 로고    scopus 로고
    • Computerized assessment of production of multiple human cytokines at the single-cell level using image analysis
    • Bjork L, Fehniger T, Andersson U, Andersson J. Computerized assessment of production of multiple human cytokines at the single-cell level using image analysis. J Leukoc Biol 1996;59:287-95.
    • (1996) J Leukoc Biol , vol.59 , pp. 287-295
    • Bjork, L.1    Fehniger, T.2    Andersson, U.3    Andersson, J.4
  • 30
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lec JC, Laydon JT, McDonnell PC, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1995;372:739-46.
    • (1995) Nature , vol.372 , pp. 739-746
    • Lec, J.C.1    Laydon, J.T.2    McDonnell, P.C.3
  • 31
    • 0013468657 scopus 로고    scopus 로고
    • P38 Mitogen-activated protein kinase (MAPK) participates in T lymphocyte co-stimulation
    • Cohen PS, Dennis J, Sherry B, et al. p38 Mitogen-activated protein kinase (MAPK) participates in T lymphocyte co-stimulation [Abstract]. Blood 1997;88(I):465a.
    • (1997) Blood , vol.88 , Issue.1
    • Cohen, P.S.1    Dennis, J.2    Sherry, B.3
  • 32
    • 0029991493 scopus 로고    scopus 로고
    • CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency
    • Cohen PS, Nakshastri H, Dennis J, et al. CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency. Proc Natl Acad Sci USA 1996;93:3967-71.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3967-3971
    • Cohen, P.S.1    Nakshastri, H.2    Dennis, J.3
  • 33
    • 0345611112 scopus 로고    scopus 로고
    • A macrophage-secreted protein mediates the macrophage-pacifying activity of CNI-1493
    • Wang H, Zhang M, Cerami C, Sherry B, Tracey KJ. A macrophage-secreted protein mediates the macrophage-pacifying activity of CNI-1493 [Abstract]. Shock 1997;7:92.
    • (1997) Shock , vol.7 , pp. 92
    • Wang, H.1    Zhang, M.2    Cerami, C.3    Sherry, B.4    Tracey, K.J.5
  • 35
    • 0031262936 scopus 로고    scopus 로고
    • Tumor necrosis factor is a brain damaging cytokine in cerebral ischemia
    • Meistrell III ME, Botchkina GI, Wang H, et al. Tumor necrosis factor is a brain damaging cytokine in cerebral ischemia. Shock 1997;8:5, 341-8.
    • (1997) Shock , vol.8 , Issue.5 , pp. 341-348
    • Meistrell M.E. III1    Botchkina, G.I.2    Wang, H.3
  • 36
    • 0030965838 scopus 로고    scopus 로고
    • Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: A counter regulatory mechanism that restrains the immune response
    • Zhang M, Caragine T, Wang H, et al. Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: a counter regulatory mechanism that restrains the immune response. J Exp Med 1997;185:10, 1759-68.
    • (1997) J Exp Med , vol.185 , pp. 10
    • Zhang, M.1    Caragine, T.2    Wang, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.