Chlamydia pneumoniae-specific cell-mediated and humoral immunity in healthy people

Scandinavian Journal of Immunology

Volumn 47, Issue 5, 1998, Pages 517-520

  Halme, S ^a,b   Von Hertzen, L ^a   Bloigu, A ^a   Kaprio, J ^c   Koskenvuo, M ^d   Leinonen, M ^a   Saikku, P ^b   Surcel, H M ^a  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b UNIVERSITY OF OULU   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G ANTIBODY;

ADULT; ANTIBODY TITER; ARTICLE; CELLULAR IMMUNITY; CHLAMYDIASIS; CHLAMYDOPHILA PNEUMONIAE; FEMALE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; LYMPHOCYTE PROLIFERATION; MALE; NORMAL HUMAN; PRIORITY JOURNAL;

ADULT; ANTIBODIES, BACTERIAL; ANTIBODY FORMATION; ANTIBODY SPECIFICITY; ANTIGENS, BACTERIAL; CHLAMYDIA INFECTIONS; CHLAMYDOPHILA PNEUMONIAE; FEMALE; FINLAND; HUMANS; IMMUNITY, CELLULAR; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; PREVALENCE; SEX FACTORS; TITRIMETRY;

EID: 0031799941     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1998.00332.x     Document Type: Article

References (16)

1. Grayston JT, Campbell LA, Kuo C-C et al. A new respiratory tract pathogen: Chlamydia pneumonia strain TWAR. J Infect Dis 1990;161:618-25.
2. Kuo C-C, Jackson LA, Campbell LA, Grayston JT. Chlamydia pneumoniae (TWAR). Clin Microbiol Rev 1995;8:451-61.
3. Saikku P, Leinonen M, Mattila K et al. Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction. Lancet 1988;ii:983-6.
4. Juvonen J, Juvonen T, Laurila A et al. Demonstration of Chlamydia pneumoniae in the walls of abdominal aortic aneurysms. J Vasc Surg 1997;25:499-505.
5. Ward ME. An update on the immunology of chlamydial infection. In: Stary A, ed. Proceedings of the Third Meeting of the European Society for Chlamydia Research, Vienna, Austria. Bologna: Societa Editrice Esculapio, 1996:58-62.
6. Johansson M, Schön K, Ward M, Lycke N. Studies in knockout mice reveal that anti-chlamydial protection requires Th1 cells producing IFN-γ : Is this true for humans? Scand J Immunol 1997;46:546-52.
7. Rank RG, Bavoil PM. Prospects for a vaccine against Chlamydia genital disease II. - Immunity and vaccine development. Bull Inst Pasteur 1996;94:55-82.
8. Surcel H-M, Syrjälä H, Leinonen M, Saikku P, Herva E. Cell-mediated immunity to Chlamydia pneumoniae measured as lymphocyte blast transformation in vitro. Infect Immun 1993;61:2196-9.
9. Halme S, Syrjälä H, Bloigu A et al. Lymphocyte responses to Chlamydia antigens in patients with coronary heart disease. Eur Heart J 1997;18:1095-1101.
10. Wang S-P, Grayston JT. Immunologic relationship between genital TRIG, lymphogranuloma venereum, and related organisms in a new microtiter indirect immunofluorescence test. Am J Ophthalmol 1970;70:367-74.
11. Ekman MR, Grayston JT, Visakorpi R, Kleemola M, Kuo C-C, Saikku P. An epidemic of infections due to Chlamydia pneumoniae in military conscripts. Clin Infect Dis 1993;17:420-5.
12. Mabey DCW, Holland MJ, Viswalingam ND et al. Lymphocyte proliferate responses to chlamydial antigens in human chlamydial eye infections. Clin Exp Immunol 1991;86:37-42.
13. Brunham RC, Martin DH, Stevens CE, Hubbard T, Holmes KK. Cellular immune response during uncomplicated genital infection with Chlamydia trachomatis in humans. Infect Immun 1981;34:98-104.
14. von Hertzen L, Surcel HM, Kaprio J et al. Effect of smoking on humoral and cell-mediated immune response to C. pneumoniae. In: Stary A, ed. Proceedings of the Third Meeting of the European Society for Chlamydia Research, Vienna, Austria. Bologna: Societa Editrice Esculapio, 1996:91.
15. Holland MJ, Bailey RL, Hayes LJ, Whittle HC, Mabey DCW. Conjunctival scarring in trachoma is associated with depressed cell-mediated immune responses to chlamydial antigens. J Infect Dis 1993;168:1528-31.
16. Young E, Taylor HR. Immune mechanisms in chlamydial eye infection: Cellular immune responses in chronic and acute disease. J Infect Dis 1984;150:745-51.