Peroral sustained-release film-coated pellets as a means to overcome physicochemical and biological drug-related problems. II. Bioavailability and tolerance assessment in dogs

Drug Development and Industrial Pharmacy

Volumn 24, Issue 6, 1998, Pages 517-525

  Timmermans, J ^a   Amighi, K ^b   Puigdevall, J ^a   Baltes, E ^a   Moes A J ^b  

^a UCB PHARMA   (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

UCB 11056; UCB 26201; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; DOG; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG RELEASE; DRUG TOLERANCE; FEMALE; HALF LIFE TIME; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PH MEASUREMENT; PHYSICAL CHEMISTRY; SUSTAINED RELEASE PREPARATION;

EID: 0031799676     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.3109/03639049809085652     Document Type: Article

References (12)

1. K. Amighi, J. Timmermans, J. Puigdevall, E. Baltes, and A. J. Moës, Drug Dev. Ind. Pharm., 24(6), 509-515 (1998).
2. K. A. Kelly, in Physiology of the Gastrointestinal Tract (L. R. Johnson, ed.), Raven Press, New York, 1981, pp. 393-410.
3. S. C. Porter, Multiparticulate oral drug delivery, in Drugs and Pharmaceutical Science, Vol. 65 (I. Ghebre-Sellassie, ed.), Marcel Dekker, Inc., New York, 1994, pp. 217-284.
4. N. Aoyagi, H. Ogata, N. Kaniwa, M. Koibuchi, T. Shibazaki, and A. Ejima, J. Pharm. Sci., 71, 1169-1172 (1982).
5. N. Aoyagi, H. Ogata, N. Kaniwa, M. Uchiyama, Y. Yasuda, and Y. Tanioka, J. Pharm. Sci., 81, 1170-1174 (1992).
6. J. B. Dressman, Pharm. Res., 3, 123-131 (1986).
7. M. Vandewalle, M. Fagoo, E. Baltes, and L. Brouwers, UCB Internal Report No. LE90A221, 1990.
8. American College of Clinical Pharmacy, J. Clin. Pharmacol., suppl. 22, S1-S23 (1982).
9. D. J. Schuirman, J. Pharmacokin. Biopharm., 715, 657-680 (1987).
10. E. C., Investigation of bioavailability and bioequivalence. Rules governing medicinal products in the European Community, III, 159-161 (1989).
11. V. W. Steinijans and D. Hauschke, Int. J. Clin. Pharmacol. Therap. Toxicol., 28, 3, 105-110 (1990).
12. C. Y. Lui, L. Amidon, R. R. Berardi, D. Fleisher, D. Youngberg, and J. B. Dressman, J. Pharm. Sci., 75, 271-274 (1986).